辐射诱发的鼻咽部骨肉瘤病例报告：揭露其后果。

IF 0.4 Q4 SURGERY

Indian Journal of Otolaryngology and Head and Neck Surgery Pub Date : 2025-08-01 Epub Date: 2025-06-18 DOI:10.1007/s12070-025-05533-1

Roshini Balu, Shrutikant Bhatia, Akash Dhiman, Sweety Gupta, Prashant Durgapal, Manoj Gupta

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引用次数: 0

摘要

放射治疗通常用于头颈部癌症的根治性治疗，具有决定性和辅助作用。随着肿瘤预后的改善，在这些癌症的长期幸存者中，第二种恶性肿瘤的发生率不断上升。放射诱导的骨肉瘤（RIOS）是一种罕见的恶性肿瘤，是放射治疗的晚期后果。它通常发生在受照射区域，治疗完成后潜伏期为5至20年。然而，在较短的潜伏期（如2年）内出现的RIOS病例是散发的和高度不典型的。本报告提出一例RIOS，强调临床过程，诊断挑战，和管理策略的侵略性继发性恶性肿瘤。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Case Report on Radiation-Induced Osteosarcoma of the Nasopharynx: Unmasking the Aftermath.

Radiotherapy is commonly used in the curative treatment of head and neck cancers, serving both definitive and adjuvant roles. As oncologic outcomes improve, there is a rising occurrence of second malignancies among long-term survivors of these cancers. Radiation-induced osteosarcoma (RIOS) is an uncommon malignancy that emerges as a late consequence of radiotherapy. It usually develops within the irradiated area with a latency period of 5 to 20 years after treatment completion. However, cases of RIOS manifesting within a much shorter latency period, such as 2 years, are sporadic and highly atypical. This report presents a case of RIOS, highlighting the clinical course, diagnostic challenges, and management strategies of this aggressive secondary malignancy.

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来源期刊

Indian Journal of Otolaryngology and Head and Neck Surgery Medicine-Otorhinolaryngology

CiteScore

0.80

自引率

0.00%

发文量

226

审稿时长

6-12 weeks

期刊介绍： Indian Journal of Otolaryngology and Head & Neck Surgery was founded as Indian Journal of Otolaryngology in 1949 as a scientific Journal published by the Association of Otolaryngologists of India and was later rechristened as IJOHNS to incorporate the changes and progress. IJOHNS, undoubtedly one of the oldest Journals in India, is the official publication of the Association of Otolaryngologists of India and is about to publish it is 67th Volume in 2015. The Journal published quarterly accepts articles in general Oto-Rhino-Laryngology and various subspecialities such as Otology, Rhinology, Laryngology and Phonosurgery, Neurotology, Head and Neck Surgery etc. The Journal acts as a window to showcase and project the clinical and research work done by Otolaryngologists community in India and around the world. It is a continued source of useful clinical information with peer review by eminent Otolaryngologists of repute in their respective fields. The Journal accepts articles pertaining to clinical reports, Clinical studies, Research articles in basic and applied Otolaryngology, short Communications, Clinical records reporting unusual presentations or lesions and new surgical techniques. The journal acts as a catalyst and mirrors the Indian Otolaryngologist’s active interests and pursuits. The Journal also invites articles from senior and experienced authors on interesting topics in Otolaryngology and allied sciences from all over the world. The print version is distributed free to about 4000 members of Association of Otolaryngologists of India and the e-Journal shortly going to make its appearance on the Springer Board can be accessed by all the members. Association of Otolaryngologists of India and M/s Springer India group have come together to co-publish IJOHNS from January 2007 and this bondage is going to provide an impetus to the Journal in terms of international presence and global exposure.