Khanh Tan Tran, József Virga, Nour Kurdi, Krisztina Ajna Chalupa, Bernadett Szűcs, Álmos Klekner, Attila Mokanszki, Judit Bedekovics
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Metastatic Supratentorial Ependymoma: A Case Presentation and Systematic Review of the Literature.
Ependymomas are categorized based on anatomical location and specific genetic alterations, with extra-axial metastasis being a rare event, occurring in less than 1% of cases and documented sparsely in the literature. This case study details a 27-year-old male patient diagnosed with supratentorial ependymoma characterized by Zinc Finger Translocation Associated (ZFTA) fusion and World Health Organization (WHO) Grade 2 morphology. Additionally, a systematic review of all reported cases of extra-axial ependymoma metastases was conducted, systematically compiling clinical, morphological, and molecular data from relevant articles. Metastatic ependymoma represents a rare occurrence characterized by diagnostic and therapeutic challenges. A comprehensive review of the literature could provide valuable insights into the underlying biology and support the selection of optimal treatment strategies for such cases.
期刊介绍：
Neuropathology is an international journal sponsored by the Japanese Society of Neuropathology and publishes peer-reviewed original papers dealing with all aspects of human and experimental neuropathology and related fields of research. The Journal aims to promote the international exchange of results and encourages authors from all countries to submit papers in the following categories: Original Articles, Case Reports, Short Communications, Occasional Reviews, Editorials and Letters to the Editor. All articles are peer-reviewed by at least two researchers expert in the field of the submitted paper.
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