Oral mucosal papilloma: A typical clinical case

Oral papilloma is a benign lesion of viral origin, mainly associated with infection by human papillomavirus (HPV) types 6 and 11. Clinically, it presents as a pedunculated or sessile growth, often asymptomatic, with a papillomatous surface. This article reports a clinical case of a 31-year-old patient with no particular medical history, presenting with a verrucous lesion localized to the anterior lingual region. Surgical excision allowed for histopathological diagnosis confirming a benign oral papilloma, without signs of dysplasia or malignancy. The discussion addresses differential diagnosis with other papillomatous lesions, notably condyloma acuminatum and focal epithelial hyperplasia, and emphasizes the importance of histology in the final diagnosis. Post-operative follow-up was favorable, with no recurrence to date. This case illustrates the importance of a rigorous diagnostic approach when faced with an oral exophytic lesion, even in the absence of symptoms or risk factors.