点阵放疗治疗同步egfr突变肺腺癌和小细胞肺癌的广泛肝转移

IF 2.7 3区医学 Q3 ONCOLOGY

Clinical and Translational Radiation Oncology Pub Date : 2025-07-23 DOI:10.1016/j.ctro.2025.101023

Shaïma El Chammah , Mickael Bendahman , Sarah Ghandour , Loris Fuchs , Rémy Kinj , Gian Guyer , Mahmut Ozsahin

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引用次数: 0

摘要

我们报告了一例同步肺腺癌和小细胞肺癌患者在晶格放射治疗（L-RT）后出现大量肝转移的特殊反应。在16 Gy的单次照射至转移性肝脏负荷的1%后，患者在一周内报告腹部症状改善。在两周内，肝脏体积减少了50%，肝酶水平稳定或改善。这个病例强调了L-RT是治疗有症状的肝转移的一种新颖有效的方法。

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Lattice radiotherapy for extensive liver metastases in synchronous EGFR-mutant lung adenocarcinoma and small cell lung cancer

We report the case of exceptional response of massive liver metastases of a patient with synchronous lung adenocarcinoma and small cell lung cancer following lattice radiotherapy (L-RT). After a single irradiation of 16 Gy to 1 % of the metastatic liver burden, the patient reported improved abdominal symptoms within a week. Within two weeks liver volume decreased by 50 %, and liver enzyme levels stabilized or improved. This case highlights L-RT as a novel and effective approach to treat symptomatic liver metastases.

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