{"title":"自身免疫性皮肤病","authors":"Guy Fletcher, Kathy Taghipour","doi":"10.1016/j.mpmed.2025.05.008","DOIUrl":null,"url":null,"abstract":"<div><div>Autoimmune blistering diseases are a rare group of disorders characterized by blistering and/or erosions of the skin and/or mucous membranes. There may be associated skin fragility and scarring. An accurate and timely diagnosis affects the management and prognosis. This is usually achieved through a careful history, thorough mucocutaneous examination and histology and immunofluorescence tests of skin and serum. It is important to determine the level of blister formation as this distinguishes subepidermal from intraepidermal diseases.</div></div>","PeriodicalId":74157,"journal":{"name":"Medicine (Abingdon, England : UK ed.)","volume":"53 8","pages":"Pages 504-511"},"PeriodicalIF":0.0000,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Autoimmune blistering skin diseases\",\"authors\":\"Guy Fletcher, Kathy Taghipour\",\"doi\":\"10.1016/j.mpmed.2025.05.008\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Autoimmune blistering diseases are a rare group of disorders characterized by blistering and/or erosions of the skin and/or mucous membranes. There may be associated skin fragility and scarring. An accurate and timely diagnosis affects the management and prognosis. This is usually achieved through a careful history, thorough mucocutaneous examination and histology and immunofluorescence tests of skin and serum. It is important to determine the level of blister formation as this distinguishes subepidermal from intraepidermal diseases.</div></div>\",\"PeriodicalId\":74157,\"journal\":{\"name\":\"Medicine (Abingdon, England : UK ed.)\",\"volume\":\"53 8\",\"pages\":\"Pages 504-511\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-06-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Medicine (Abingdon, England : UK ed.)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S135730392500129X\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medicine (Abingdon, England : UK ed.)","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S135730392500129X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Autoimmune blistering diseases are a rare group of disorders characterized by blistering and/or erosions of the skin and/or mucous membranes. There may be associated skin fragility and scarring. An accurate and timely diagnosis affects the management and prognosis. This is usually achieved through a careful history, thorough mucocutaneous examination and histology and immunofluorescence tests of skin and serum. It is important to determine the level of blister formation as this distinguishes subepidermal from intraepidermal diseases.
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