{"title":"社区获得性肺炎","authors":"Sjoerd HW van Bree, Shady Amer","doi":"10.1016/j.mpaic.2025.05.013","DOIUrl":null,"url":null,"abstract":"<div><div>Community-acquired pneumonia (CAP) is a condition characterized by inflammatory changes in the respiratory system caused by non-hospital pathogens. The symptoms and signs of a lower respiratory tract infection range from cough, dyspnoea, pleuritic chest pain, sputum with mucopurulent components, to systemic features such as myalgia, and fever. Patients in their older years are more likely to present with confusion or worsening pre-existing conditions and may lack fever. Severe CAP is a pneumonia that requires supportive therapy within intensive care settings, and is still associated with a high mortality and significantly morbidity, specifically amongst the elderly population with multiple comorbidities. Despite the improvement in supportive care by new modalities, such as high-flow nasal oxygen therapy, severe CAP remains one of the most common reasons for admission to a critical care facility. Correct diagnosis, risk stratification and early initiation of antibiotic treatment are key factors determining outcomes of patients with severe CAP. New developments will concentrate on diagnostics such as point of care microbiological tests and adjuvant non-antibiotic immunomodulating treatment strategies. Neither coronavirus disease (COVID-19) pneumonia nor pneumonia in immunocompromised patients are within the scope of this article.</div></div>","PeriodicalId":45856,"journal":{"name":"Anaesthesia and Intensive Care Medicine","volume":"26 8","pages":"Pages 491-497"},"PeriodicalIF":0.3000,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Community-acquired pneumonia\",\"authors\":\"Sjoerd HW van Bree, Shady Amer\",\"doi\":\"10.1016/j.mpaic.2025.05.013\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Community-acquired pneumonia (CAP) is a condition characterized by inflammatory changes in the respiratory system caused by non-hospital pathogens. The symptoms and signs of a lower respiratory tract infection range from cough, dyspnoea, pleuritic chest pain, sputum with mucopurulent components, to systemic features such as myalgia, and fever. Patients in their older years are more likely to present with confusion or worsening pre-existing conditions and may lack fever. Severe CAP is a pneumonia that requires supportive therapy within intensive care settings, and is still associated with a high mortality and significantly morbidity, specifically amongst the elderly population with multiple comorbidities. Despite the improvement in supportive care by new modalities, such as high-flow nasal oxygen therapy, severe CAP remains one of the most common reasons for admission to a critical care facility. Correct diagnosis, risk stratification and early initiation of antibiotic treatment are key factors determining outcomes of patients with severe CAP. New developments will concentrate on diagnostics such as point of care microbiological tests and adjuvant non-antibiotic immunomodulating treatment strategies. Neither coronavirus disease (COVID-19) pneumonia nor pneumonia in immunocompromised patients are within the scope of this article.</div></div>\",\"PeriodicalId\":45856,\"journal\":{\"name\":\"Anaesthesia and Intensive Care Medicine\",\"volume\":\"26 8\",\"pages\":\"Pages 491-497\"},\"PeriodicalIF\":0.3000,\"publicationDate\":\"2025-07-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Anaesthesia and Intensive Care Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1472029925001146\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"ANESTHESIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Anaesthesia and Intensive Care Medicine","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1472029925001146","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"ANESTHESIOLOGY","Score":null,"Total":0}
Community-acquired pneumonia (CAP) is a condition characterized by inflammatory changes in the respiratory system caused by non-hospital pathogens. The symptoms and signs of a lower respiratory tract infection range from cough, dyspnoea, pleuritic chest pain, sputum with mucopurulent components, to systemic features such as myalgia, and fever. Patients in their older years are more likely to present with confusion or worsening pre-existing conditions and may lack fever. Severe CAP is a pneumonia that requires supportive therapy within intensive care settings, and is still associated with a high mortality and significantly morbidity, specifically amongst the elderly population with multiple comorbidities. Despite the improvement in supportive care by new modalities, such as high-flow nasal oxygen therapy, severe CAP remains one of the most common reasons for admission to a critical care facility. Correct diagnosis, risk stratification and early initiation of antibiotic treatment are key factors determining outcomes of patients with severe CAP. New developments will concentrate on diagnostics such as point of care microbiological tests and adjuvant non-antibiotic immunomodulating treatment strategies. Neither coronavirus disease (COVID-19) pneumonia nor pneumonia in immunocompromised patients are within the scope of this article.
期刊介绍:
Anaesthesia and Intensive Care Medicine, an invaluable source of up-to-date information, with the curriculum of both the Primary and Final FRCA examinations covered over a three-year cycle. Published monthly this ever-updating text book will be an invaluable source for both trainee and experienced anaesthetists. The enthusiastic editorial board, under the guidance of two eminent and experienced series editors, ensures Anaesthesia and Intensive Care Medicine covers all the key topics in a comprehensive and authoritative manner. Articles now include learning objectives and eash issue features MCQs, facilitating self-directed learning and enabling readers at all levels to test their knowledge. Each issue is divided between basic scientific and clinical sections. The basic science articles include anatomy, physiology, pharmacology, physics and clinical measurement, while the clinical sections cover anaesthetic agents and techniques, assessment and perioperative management. Further sections cover audit, trials, statistics, ethical and legal medicine, and the management of acute and chronic pain.