Elisabeth L. Nielsen , Andreas W. Nielsen , Agnete O. Donskov , Christoffer S. Våben , Line L. Frølund , Ib T. Hansen , Line T. Moll , Berit D. Nielsen , Christoffer Mørk , Ellen M. Hauge , Kresten K. Keller
{"title":"快速获取策略对疑似风湿性多肌痛患者转诊率、诊断和糖皮质激素启动的影响","authors":"Elisabeth L. Nielsen , Andreas W. Nielsen , Agnete O. Donskov , Christoffer S. Våben , Line L. Frølund , Ib T. Hansen , Line T. Moll , Berit D. Nielsen , Christoffer Mørk , Ellen M. Hauge , Kresten K. Keller","doi":"10.1016/j.semarthrit.2025.152793","DOIUrl":null,"url":null,"abstract":"<div><h3>Objectives</h3><div>Diagnosing polymyalgia rheumatica (PMR) is difficult, and 50 % have initiated glucocorticoids (GC) before rheumatological evaluation, challenging the distinction from other conditions. Rapid access strategy (RAS) clinics for individuals with suspected PMR may reduce GC initiation before rheumatological evaluation, but evidence is limited. This study evaluates the impact of a RAS clinic compared with a traditional referral approach for individuals with suspected PMR.</div></div><div><h3>Methods</h3><div>This single-centre retrospective cohort study compared individuals suspected of PMR referred to a RAS clinic with a historical cohort. Comparisons included referral rates, time from referral to evaluation, diagnosis, and GC initiation before evaluation.</div></div><div><h3>Results</h3><div>Referral rates almost doubled after the RAS clinic was implemented with modest change in the proportion diagnosed with PMR at evaluation (70 % [95 % CI: 62–77] vs. 59 % [95 % CI: 52–65]). Compared with the historical cohort, more individuals in the RAS cohort were evaluated within one week (55 % [95 % CI: 49–62] vs. 36 % [95 % CI: 28–44]) and two weeks (89 % [95 % CI: 84–92] vs. 75 % [95 % CI: 67–81]). Additionally, fewer individuals initiated GCs before evaluation (9 % [95 % CI: 6–13] vs. 20 % [95 % CI: 15–28]) and fewer patients received GCs one year after diagnosis (50 % [95 % CI: 39–61] vs. 77 % [95 % CI: 62–89]). The proportion with subclinical giant cell arteritis remained low.</div></div><div><h3>Conclusion</h3><div>Implementation of a RAS clinic for individuals with suspected PMR increased referral rates, while modestly reducing the proportion diagnosed with PMR, and lowered the proportion of individuals initiating GCs before evaluation.</div></div>","PeriodicalId":21715,"journal":{"name":"Seminars in arthritis and rheumatism","volume":"74 ","pages":"Article 152793"},"PeriodicalIF":4.4000,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Impact of a rapid access strategy on referral rates, diagnosis, and glucocorticoid initiation in suspected polymyalgia rheumatica\",\"authors\":\"Elisabeth L. Nielsen , Andreas W. Nielsen , Agnete O. Donskov , Christoffer S. Våben , Line L. Frølund , Ib T. Hansen , Line T. Moll , Berit D. Nielsen , Christoffer Mørk , Ellen M. Hauge , Kresten K. Keller\",\"doi\":\"10.1016/j.semarthrit.2025.152793\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objectives</h3><div>Diagnosing polymyalgia rheumatica (PMR) is difficult, and 50 % have initiated glucocorticoids (GC) before rheumatological evaluation, challenging the distinction from other conditions. Rapid access strategy (RAS) clinics for individuals with suspected PMR may reduce GC initiation before rheumatological evaluation, but evidence is limited. This study evaluates the impact of a RAS clinic compared with a traditional referral approach for individuals with suspected PMR.</div></div><div><h3>Methods</h3><div>This single-centre retrospective cohort study compared individuals suspected of PMR referred to a RAS clinic with a historical cohort. Comparisons included referral rates, time from referral to evaluation, diagnosis, and GC initiation before evaluation.</div></div><div><h3>Results</h3><div>Referral rates almost doubled after the RAS clinic was implemented with modest change in the proportion diagnosed with PMR at evaluation (70 % [95 % CI: 62–77] vs. 59 % [95 % CI: 52–65]). Compared with the historical cohort, more individuals in the RAS cohort were evaluated within one week (55 % [95 % CI: 49–62] vs. 36 % [95 % CI: 28–44]) and two weeks (89 % [95 % CI: 84–92] vs. 75 % [95 % CI: 67–81]). Additionally, fewer individuals initiated GCs before evaluation (9 % [95 % CI: 6–13] vs. 20 % [95 % CI: 15–28]) and fewer patients received GCs one year after diagnosis (50 % [95 % CI: 39–61] vs. 77 % [95 % CI: 62–89]). The proportion with subclinical giant cell arteritis remained low.</div></div><div><h3>Conclusion</h3><div>Implementation of a RAS clinic for individuals with suspected PMR increased referral rates, while modestly reducing the proportion diagnosed with PMR, and lowered the proportion of individuals initiating GCs before evaluation.</div></div>\",\"PeriodicalId\":21715,\"journal\":{\"name\":\"Seminars in arthritis and rheumatism\",\"volume\":\"74 \",\"pages\":\"Article 152793\"},\"PeriodicalIF\":4.4000,\"publicationDate\":\"2025-07-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Seminars in arthritis and rheumatism\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0049017225001647\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"RHEUMATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Seminars in arthritis and rheumatism","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0049017225001647","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"RHEUMATOLOGY","Score":null,"Total":0}
Impact of a rapid access strategy on referral rates, diagnosis, and glucocorticoid initiation in suspected polymyalgia rheumatica
Objectives
Diagnosing polymyalgia rheumatica (PMR) is difficult, and 50 % have initiated glucocorticoids (GC) before rheumatological evaluation, challenging the distinction from other conditions. Rapid access strategy (RAS) clinics for individuals with suspected PMR may reduce GC initiation before rheumatological evaluation, but evidence is limited. This study evaluates the impact of a RAS clinic compared with a traditional referral approach for individuals with suspected PMR.
Methods
This single-centre retrospective cohort study compared individuals suspected of PMR referred to a RAS clinic with a historical cohort. Comparisons included referral rates, time from referral to evaluation, diagnosis, and GC initiation before evaluation.
Results
Referral rates almost doubled after the RAS clinic was implemented with modest change in the proportion diagnosed with PMR at evaluation (70 % [95 % CI: 62–77] vs. 59 % [95 % CI: 52–65]). Compared with the historical cohort, more individuals in the RAS cohort were evaluated within one week (55 % [95 % CI: 49–62] vs. 36 % [95 % CI: 28–44]) and two weeks (89 % [95 % CI: 84–92] vs. 75 % [95 % CI: 67–81]). Additionally, fewer individuals initiated GCs before evaluation (9 % [95 % CI: 6–13] vs. 20 % [95 % CI: 15–28]) and fewer patients received GCs one year after diagnosis (50 % [95 % CI: 39–61] vs. 77 % [95 % CI: 62–89]). The proportion with subclinical giant cell arteritis remained low.
Conclusion
Implementation of a RAS clinic for individuals with suspected PMR increased referral rates, while modestly reducing the proportion diagnosed with PMR, and lowered the proportion of individuals initiating GCs before evaluation.
期刊介绍:
Seminars in Arthritis and Rheumatism provides access to the highest-quality clinical, therapeutic and translational research about arthritis, rheumatology and musculoskeletal disorders that affect the joints and connective tissue. Each bimonthly issue includes articles giving you the latest diagnostic criteria, consensus statements, systematic reviews and meta-analyses as well as clinical and translational research studies. Read this journal for the latest groundbreaking research and to gain insights from scientists and clinicians on the management and treatment of musculoskeletal and autoimmune rheumatologic diseases. The journal is of interest to rheumatologists, orthopedic surgeons, internal medicine physicians, immunologists and specialists in bone and mineral metabolism.