{"title":"床边强离子分析","authors":"Freddie Hopkinson, Ryan Hughes, Matthew J Brain","doi":"10.1016/j.mpaic.2025.05.003","DOIUrl":null,"url":null,"abstract":"<div><div>Stewart's quantitative physicochemical model of human acid-base physiology filled a void between clinical acid–base analysis and general fluid physiology. The physicochemical model is frequently perceived as too complex for bedside use, however a set of simplified screening questions based on Stewart's model can be utilized to aid acid–base interpretation. Emphasis is placed on understanding the acid–base consequences of hypoalbuminaemia, volume status, tonicity and chloride as these are common in intensive care unit patients.</div></div>","PeriodicalId":45856,"journal":{"name":"Anaesthesia and Intensive Care Medicine","volume":"26 8","pages":"Pages 477-485"},"PeriodicalIF":0.3000,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Strong ion analysis at the bedside\",\"authors\":\"Freddie Hopkinson, Ryan Hughes, Matthew J Brain\",\"doi\":\"10.1016/j.mpaic.2025.05.003\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Stewart's quantitative physicochemical model of human acid-base physiology filled a void between clinical acid–base analysis and general fluid physiology. The physicochemical model is frequently perceived as too complex for bedside use, however a set of simplified screening questions based on Stewart's model can be utilized to aid acid–base interpretation. Emphasis is placed on understanding the acid–base consequences of hypoalbuminaemia, volume status, tonicity and chloride as these are common in intensive care unit patients.</div></div>\",\"PeriodicalId\":45856,\"journal\":{\"name\":\"Anaesthesia and Intensive Care Medicine\",\"volume\":\"26 8\",\"pages\":\"Pages 477-485\"},\"PeriodicalIF\":0.3000,\"publicationDate\":\"2025-07-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Anaesthesia and Intensive Care Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1472029925001043\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"ANESTHESIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Anaesthesia and Intensive Care Medicine","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1472029925001043","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"ANESTHESIOLOGY","Score":null,"Total":0}
Stewart's quantitative physicochemical model of human acid-base physiology filled a void between clinical acid–base analysis and general fluid physiology. The physicochemical model is frequently perceived as too complex for bedside use, however a set of simplified screening questions based on Stewart's model can be utilized to aid acid–base interpretation. Emphasis is placed on understanding the acid–base consequences of hypoalbuminaemia, volume status, tonicity and chloride as these are common in intensive care unit patients.
期刊介绍:
Anaesthesia and Intensive Care Medicine, an invaluable source of up-to-date information, with the curriculum of both the Primary and Final FRCA examinations covered over a three-year cycle. Published monthly this ever-updating text book will be an invaluable source for both trainee and experienced anaesthetists. The enthusiastic editorial board, under the guidance of two eminent and experienced series editors, ensures Anaesthesia and Intensive Care Medicine covers all the key topics in a comprehensive and authoritative manner. Articles now include learning objectives and eash issue features MCQs, facilitating self-directed learning and enabling readers at all levels to test their knowledge. Each issue is divided between basic scientific and clinical sections. The basic science articles include anatomy, physiology, pharmacology, physics and clinical measurement, while the clinical sections cover anaesthetic agents and techniques, assessment and perioperative management. Further sections cover audit, trials, statistics, ethical and legal medicine, and the management of acute and chronic pain.