临床海洋生物医学:临床和转化医学的新兴领域

IF 1.9
Xiaojun Yan, Wanxin Duan, Xiangdong Wang
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引用次数: 0

摘要

海洋生物医学是海洋学和生物生态系统的一个重要领域,随着生物技术的进步和对海洋生物的认识不断加深,海洋生物医学得到了显著的发展。从这个角度来看,我们提出了一个精炼的临床海洋生物医学概念,并明确了建立一个连接海洋生物医学和临床实践的新兴学科的使命。应强调对海洋来源的探索,重点是确定、验证和开发针对人类疾病的诊断方法和面向目标的药物。该展望概述了一些关键组成部分,包括以海洋为导向的人类进化和发展、人性化的海洋模型、生物标志物创新和验证、海洋微生物组和代谢物,以及目标营养和治疗。我们展望临床海洋生物医学将成为临床分子医学的重要支柱,为改善人类健康和患者预后做出贡献。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Clinical marine biomedicine: An emerging area in clinical and translational medicine

Clinical marine biomedicine: An emerging area in clinical and translational medicine

Marine biomedicine is an important field in oceanology and bio-ecosystem and has evolved significantly alongside advances in biotechnology and growing understanding of marine life. In this perspective, we propose a refined concept of clinical marine biomedicine, with a clear mission to establish an emerging discipline that bridges marine biomedicine and clinical practice. The exploration of marine-origin sources should be emphasised, with a strong focus on the identification, validation and development of human disease-specific diagnostics and target-oriented pharmaceutics. The perspective headlines some of critical components, including marine-oriented human evolution and development, humanised marine-based models, biomarker innovation and validation, marine microbiomes and metabolites, and target nutrition and therapy. We envision that clinical marine biomedicine will become a crucial pillar clinical molecular medicine, contributing to the improvement of human health and the prognosis of patient.

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