术后近距离放疗治疗瘢痕疙瘩:一项单中心研究。

IF 1.1 4区 医学 Q4 ONCOLOGY
Journal of Contemporary Brachytherapy Pub Date : 2025-06-01 Epub Date: 2025-06-04 DOI:10.5114/jcb.2025.151825
Irene Gonzalez-Alaña, Patricia Martin-Playa, Leire Aparicio-Elizalde, Unay Yilmaz-Bescos, Francisco Casquero-Ocio, Itziar Valverde-Pascual, Silvia Perez-Fernandez, Jaime Carames-Estefania, Iñigo San Miguel-Arregui
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引用次数: 0

摘要

目的:瘢痕疙瘩是一种良性纤维真皮肿瘤,可产生过量的细胞外基质沉积。它通常发生在皮肤损伤之后,并扩散到伤口以外。其特点是术后复发率高,缺乏自发复发的倾向。已有多种治疗方法,复发率高达100%。被认为最有效的治疗方法之一是联合治疗,即手术和随后使用间质放射治疗的铱-192(近距离放射治疗),复发率明显降低。材料与方法:本中心于2012年引进该技术,目前对27例患者进行回顾性观察研究,截至2020年12月。结果:本组复发率为25%,其中部分复发83%。结论:手术创面裂开和感染是最常见的并发症,该方法安全有效。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Post-surgical brachytherapy in the treatment of keloids: A single-center study.

Post-surgical brachytherapy in the treatment of keloids: A single-center study.

Post-surgical brachytherapy in the treatment of keloids: A single-center study.

Purpose: A keloid is a benign fibro-dermal tumor that produces an excess deposit of extra-cellular matrix. It usually occurs after a skin lesion, and it spreads beyond the wound. It is characterized by high recurrence rate after excision and lack of tendency of spontaneous involution. Multiple treatments have been described, with recurrence rates of up to 100%. One of the treatments considered most effective is combined therapy, i.e., surgery and subsequent radiotherapy using interstitial irradiation with iridium-192 (brachytherapy), with a clear reduction in recurrence rate.

Material and methods: In our center, the technique was introduced in 2012, and the current retrospective observational study was conducted among 27 patients treated till December 2020.

Results: The recurrence rate in the study was 25%, of which 83% recurred partially.

Conclusions: The most frequent complications observed were dehiscence and infection of the surgical wound, therefore this therapeutic approach can be considered both safe and effective.

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来源期刊
Journal of Contemporary Brachytherapy
Journal of Contemporary Brachytherapy ONCOLOGY-RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
CiteScore
2.40
自引率
14.30%
发文量
54
审稿时长
16 weeks
期刊介绍: The “Journal of Contemporary Brachytherapy” is an international and multidisciplinary journal that will publish papers of original research as well as reviews of articles. Main subjects of the journal include: clinical brachytherapy, combined modality treatment, advances in radiobiology, hyperthermia and tumour biology, as well as physical aspects relevant to brachytherapy, particularly in the field of imaging, dosimetry and radiation therapy planning. Original contributions will include experimental studies of combined modality treatment, tumor sensitization and normal tissue protection, molecular radiation biology, and clinical investigations of cancer treatment in brachytherapy. Another field of interest will be the educational part of the journal.
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