{"title":"多哥肝硬化患者细菌感染的患病率及相关因素","authors":"Laté Mawuli Lawson-Ananissoh, Mawunyo Henoc Gbolou, Debehoma Venceslas Redah, Lidawu Roland-Moise Kogoe, Yendoukoa Yves Kanake, Aklesso Bagny","doi":"10.1590/S0004-2803.24612024-37","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>to determine the prevalence and identify the factors associated with bacterial infection in cirrhotic patients in Togo.</p><p><strong>Methods: </strong>This was a descriptive and analytical cross-sectional study, with retrospective data collection, conducted in the hepato-gastroenterology department of the Campus University Hospital during three years. All patients hospitalized in the department during this period and diagnosed with cirrhosis were included in the study.</p><p><strong>Results: </strong>During the study period, 270 patients were hospitalized for cirrhosis including 63 cases of bacterial infection, a prevalence of 23.3%. Bacterial infections were represented by spontaneous infection of ascites fluid (15.9%) followed by urinary tract infection (4%). The median length of hospital stay was 10 days Thirty-six of the patients with infection died in hospital, corresponding to a mortality rate of 57.1%. Factors associated with bacterial infection were ascites (P=0.017; OR=4.56), hepatic encephalopathy (P=0.02; OR=4.32), a prothrombin level below 25% (P=0.002; OR=9.67) and a high MELD score (P=0.03; OR=0.93).</p><p><strong>Conclusion: </strong>Bacterial infection occurs in advanced cirrhosis and is associated with a poor prognosis.</p><p><strong>Background: </strong>• Bacterial infections are a frequent complication of cirrhosis and were associated with ascites, hepatic encephalopathy and a high MELD score.</p><p><strong>Background: </strong>• The most frequent type of infection in this study was spontaneous bacterial peritonitis followed by urinary tract infection.</p>","PeriodicalId":35671,"journal":{"name":"Arquivos de Gastroenterologia","volume":"62 ","pages":"e24037"},"PeriodicalIF":0.0000,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12289287/pdf/","citationCount":"0","resultStr":"{\"title\":\"PREVALENCE AND FACTORS ASSOCIATED WITH BACTERIAL INFECTION IN CIRRHOTIC PATIENTS IN TOGO.\",\"authors\":\"Laté Mawuli Lawson-Ananissoh, Mawunyo Henoc Gbolou, Debehoma Venceslas Redah, Lidawu Roland-Moise Kogoe, Yendoukoa Yves Kanake, Aklesso Bagny\",\"doi\":\"10.1590/S0004-2803.24612024-37\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objectives: </strong>to determine the prevalence and identify the factors associated with bacterial infection in cirrhotic patients in Togo.</p><p><strong>Methods: </strong>This was a descriptive and analytical cross-sectional study, with retrospective data collection, conducted in the hepato-gastroenterology department of the Campus University Hospital during three years. All patients hospitalized in the department during this period and diagnosed with cirrhosis were included in the study.</p><p><strong>Results: </strong>During the study period, 270 patients were hospitalized for cirrhosis including 63 cases of bacterial infection, a prevalence of 23.3%. Bacterial infections were represented by spontaneous infection of ascites fluid (15.9%) followed by urinary tract infection (4%). The median length of hospital stay was 10 days Thirty-six of the patients with infection died in hospital, corresponding to a mortality rate of 57.1%. Factors associated with bacterial infection were ascites (P=0.017; OR=4.56), hepatic encephalopathy (P=0.02; OR=4.32), a prothrombin level below 25% (P=0.002; OR=9.67) and a high MELD score (P=0.03; OR=0.93).</p><p><strong>Conclusion: </strong>Bacterial infection occurs in advanced cirrhosis and is associated with a poor prognosis.</p><p><strong>Background: </strong>• Bacterial infections are a frequent complication of cirrhosis and were associated with ascites, hepatic encephalopathy and a high MELD score.</p><p><strong>Background: </strong>• The most frequent type of infection in this study was spontaneous bacterial peritonitis followed by urinary tract infection.</p>\",\"PeriodicalId\":35671,\"journal\":{\"name\":\"Arquivos de Gastroenterologia\",\"volume\":\"62 \",\"pages\":\"e24037\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-07-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12289287/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Arquivos de Gastroenterologia\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1590/S0004-2803.24612024-37\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q2\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Arquivos de Gastroenterologia","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1590/S0004-2803.24612024-37","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}
PREVALENCE AND FACTORS ASSOCIATED WITH BACTERIAL INFECTION IN CIRRHOTIC PATIENTS IN TOGO.
Objectives: to determine the prevalence and identify the factors associated with bacterial infection in cirrhotic patients in Togo.
Methods: This was a descriptive and analytical cross-sectional study, with retrospective data collection, conducted in the hepato-gastroenterology department of the Campus University Hospital during three years. All patients hospitalized in the department during this period and diagnosed with cirrhosis were included in the study.
Results: During the study period, 270 patients were hospitalized for cirrhosis including 63 cases of bacterial infection, a prevalence of 23.3%. Bacterial infections were represented by spontaneous infection of ascites fluid (15.9%) followed by urinary tract infection (4%). The median length of hospital stay was 10 days Thirty-six of the patients with infection died in hospital, corresponding to a mortality rate of 57.1%. Factors associated with bacterial infection were ascites (P=0.017; OR=4.56), hepatic encephalopathy (P=0.02; OR=4.32), a prothrombin level below 25% (P=0.002; OR=9.67) and a high MELD score (P=0.03; OR=0.93).
Conclusion: Bacterial infection occurs in advanced cirrhosis and is associated with a poor prognosis.
Background: • Bacterial infections are a frequent complication of cirrhosis and were associated with ascites, hepatic encephalopathy and a high MELD score.
Background: • The most frequent type of infection in this study was spontaneous bacterial peritonitis followed by urinary tract infection.
期刊介绍：
The journal Arquivos de Gastroenterologia (Archives of Gastroenterology), a quarterly journal, is the Official Publication of the Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia IBEPEGE (Brazilian Institute for Studies and Research in Gastroenterology), Colégio Brasileiro de Cirurgia Digestiva - CBCD (Brazilian College of Digestive Surgery) and of the Sociedade Brasileira de Motilidade Digestiva - SBMD (Brazilian Digestive Motility Society). It is dedicated to the publishing of scientific papers by national and foreign researchers who are in agreement with the aim of the journal as well as with its editorial policies.
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