女性退伍军人完成3,4-亚甲基二氧基甲基苯丙胺（MDMA）强化短期认知行为联合治疗一例

IF 2.9 3区心理学 Q1 PSYCHOLOGY, CLINICAL

Cognitive and Behavioral Practice Pub Date : 2025-06-03 DOI:10.1016/j.cbpra.2025.01.002

Leslie A. Morland, Kayla Knopp, Bettye Chargin, Tamara R. Wachsman, Chandra Khalifian, Dimitri Perivoliotis, Anne C. Wagner

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引用次数: 0

摘要

本案例研究的重点是一名女退伍军人及其亲密伴侣参加了一项开放标签临床试验，接受了简短的认知行为联合治疗（bCBCT），并辅以两次3,4-亚甲基二氧甲基苯丙胺（MDMA）治疗创伤后应激障碍（PTSD）和关系功能。双方都参加了治疗，只有被诊断患有创伤后应激障碍的退伍军人接受了MDMA。结果显示，退伍军人PTSD症状明显减轻（治疗前cap -5严重程度为51，治疗后立即cap -5 = 22，治疗后3个月cap -5 = 28，治疗后6个月cap -5 = 21），维持较高的关系满意度（治疗前CSI-32 = 136，治疗后立即CSI-32 = 140，治疗后3个月CSI-32 = 137，治疗后6个月CSI-32 = 129）。本病例说明了一种新型的、可扩展的MDMA辅助bCBCT门诊模式，并强调了包括亲人（如亲密伴侣）在内的MDMA治疗和整合的重要性。

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A Case Example of a Female Veteran Completing Brief Cognitive Behavioral Conjoint Therapy Augmented With 3,4-methylenedioxymethamphetamine (MDMA)

This case study highlights a female military veteran and her intimate partner who participated in an open label clinical trial receiving brief Cognitive-Behavioral Conjoint Therapy (bCBCT) enhanced with two 3,4-methylenedioxymethamphetamine (MDMA) sessions to treat posttraumatic stress disorder (PTSD) and relationship functioning. Both partners participated in therapy and only the veteran diagnosed with PTSD received MDMA. Results suggest significant PTSD symptom reduction for the veteran (pretreatment CAPS-5 severity = 51, immediate posttreatment CAPS-5 = 22, 3-months posttreatment CAPS-5 = 28, and 6-months posttreatment CAPS-5 = 21) and maintenance of high relationship satisfaction (pretreatment CSI-32 = 136, immediate post CSI-32 = 140, 3-months posttreatment CSI-32 = 137, and 6-months posttreatment CSI-32 = 129). This case illustrates a novel and scalable delivery of MDMA-assisted bCBCT using an outpatient model and highlights the importance of including loved ones, such as intimate partners, in MDMA treatment and integration.

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来源期刊

Cognitive and Behavioral Practice PSYCHOLOGY, CLINICAL-

CiteScore

4.80

自引率

3.40%

发文量

118

审稿时长

84 days

期刊介绍： Cognitive and Behavioral Practice is a quarterly international journal that serves an enduring resource for empirically informed methods of clinical practice. Its mission is to bridge the gap between published research and the actual clinical practice of cognitive behavior therapy. Cognitive and Behavioral Practice publishes clinically rich accounts of innovative assessment and diagnostic and therapeutic procedures that are clearly grounded in empirical research. A focus on application and implementation of procedures is maintained.