未知的领域

Q4 Medicine

JACC. Case reports Pub Date : 2025-07-23 DOI:10.1016/j.jaccas.2025.104155

Muhammad Salman Sabri MD , Zinya Talukder DO , Naila Ijaz MD , Joseph Neri DO

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引用次数: 0

摘要

背景：心脏黏液瘤是一种良性肿瘤，通常起源于左心房，通常与卡尼综合征有关。在我们的文献综述中，没有2型神经纤维瘤病（NF2）患者发生心脏黏液瘤的病例报道。病例总结：60岁男性，以头晕表现，发现脑膜瘤和前庭神经鞘瘤，符合NF2。心脏黏液瘤是偶然通过超声心动图诊断，并经心脏磁共振成像和组织病理证实。手术切除了肿块。病人接受了基因检测；然而，他决定不再接受进一步的检查。nf2是一种遗传性常染色体显性遗传病，与前庭神经鞘瘤、脑膜瘤、室管膜瘤、白内障、晶状体混浊和视网膜错构瘤有关。需要进一步的研究来调查NF2患者心脏黏液瘤的潜在风险以及在这一人群中进行常规黏液瘤筛查的益处。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Uncharted Territory

Background

Cardiac myxoma is a benign tumor, typically originating in the left atrium, and is often linked to Carney complex. In our literature review, there are no case reports of cardiac myxoma in patients with neurofibromatosis type 2 (NF2).

Case Summary

A 60-year-old man presented with dizziness and was found to have meningioma and vestibular schwannoma, consistent with NF2. Cardiac myxoma was incidentally diagnosed through echocardiography and confirmed by cardiac magnetic resonance imaging and tissue pathology. The mass was surgically resected. The patient was offered genetic testing; however, he decided to not undergo further testing.

Discussion

NF2 is an inherited autosomal dominant disorder associated with vestibular schwannoma, meningioma, ependymoma, cataract, lenticular opacities, and retinal hamartomas.

Take-Home Message

Further research is needed to investigate the potential risk of cardiac myxoma in patients with NF2 and the benefit of routine screening for myxomas in this population.

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