产后脑室内出血1例报告及文献复习

Nikita Grace Mathews , Andrea Cuschieri , Mazhar Darwazeh , Adel Al Sisi , Kavita Krishnan , Rami Darwazeh
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摘要

产后脑出血(ICH)和脑室内出血(IVH)是罕见但可能危及生命的疾病。它们通常由高血压疾病引起,如先兆子痫。因此,围产期是监测女性患者的关键时期,特别是那些有高血压急诊风险的女性患者。临床表现女性,32岁,无高血压病史,产后7天出现严重头痛和血压升高(197/104 mmHg)。即时脑CT扫描显示存在大脑出血和IVH,累及所有4个脑室。随后,患者的格拉斯哥昏迷评分(GCS)迅速下降(从13/15-8/15),新的脑部CT扫描显示脑内和脑室内出血量增加。立即进行手术,包括减压颅骨切除术,脑出血排出和放置外脑室引流管(EVD)。术后随访6个月,根据格拉斯哥结局量表扩展(GOS-E),患者表现出明显的恢复和中上残疾,根据改进的Rankin量表评分,患者获得了3分(满分6分)。结论及时的神经外科干预,包括颅脑减压、血肿清除和EVD放置,可以显著改善产后脑出血和IVH患者的预后,即使对神经功能迅速下降的患者也是如此。当产后高血压和神经系统症状出现时,临床医生应迅速采取行动,因为早期诊断和干预对降低死亡率和长期残疾至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Postpartum intracerebral and intraventricular hemorrhage – A case report and review of the literature

Background

Postpartum intracerebral hemorrhages (ICH) and intraventricular hemorrhages (IVH) are rare but potentially life-threatening conditions. They are often precipitated by hypertensive disorders, such as preeclampsia. Thus, the peripartum period is a critical time for monitoring female patients, particularly those at risk of hypertensive emergencies.

Clinical presentation

A 32-year-old female with no previous history of hypertension presented with severe headaches and elevated blood pressure (197/104 mmHg) seven days after delivery. Immediate brain computed tomography (CT) scan revealed the presence of a large ICH and IVH involving all 4 ventricles. Subsequently, the patient’s Glasgow Coma Scale (GCS) dropped rapidly (from 13/15–8/15) and a new brain CT scan revealed an increase in the intracerebral and intraventricular hemorrhage volume. Immediate surgery was performed, which consisted of decompressive craniectomy, ICH evacuation and placement of an external ventricular drain (EVD). The patient’s postoperative course showed significant recovery with upper moderate disability at 6 months follow-up based on the Glasgow Outcome Scale Extended (GOS-E) and scoring 3 out of 6 based on a modified Rankin scale score.

Conclusion

Timely neurosurgical intervention—including decompressive craniectomy, hematoma evacuation, and EVD placement—can significantly improve outcomes in postpartum patients with ICH and IVH, even in cases with rapid neurological decline. Clinicians should act swiftly when postpartum hypertension and neurological symptoms arise, as early diagnosis and intervention are critical to reducing mortality and long-term disability.
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