Declan Devane , Johanna Pope , Paula Byrne , Evan Forde , Steven Woloshin , Eileen Culloty , Darren Dahly , Ingeborg Hess Elgersma , Heather Munthe-Kaas , Conor Judge , Martin O'Donnell , Finn Krewer , Sandra Galvin , Nikita Burke , Theresa Tierney , KM Saif-Ur-Rahman , Tom Conway , James Thomas
{"title":"Cochrane综述中人工智能辅助和人工生成的简单语言摘要的比较:一项随机试验方案(HIET-1)","authors":"Declan Devane , Johanna Pope , Paula Byrne , Evan Forde , Steven Woloshin , Eileen Culloty , Darren Dahly , Ingeborg Hess Elgersma , Heather Munthe-Kaas , Conor Judge , Martin O'Donnell , Finn Krewer , Sandra Galvin , Nikita Burke , Theresa Tierney , KM Saif-Ur-Rahman , Tom Conway , James Thomas","doi":"10.1016/j.jclinepi.2025.111894","DOIUrl":null,"url":null,"abstract":"<div><div>Plain language summaries (PLSs) of systematic reviews present complex health evidence in accessible language. Advances in artificial intelligence (AI), particularly large language models, may enhance the generation of PLSs. This protocol describes a randomized, parallel-group, two-armed, noninferiority trial comparing AI-assisted vs human-generated PLSs. Adults aged 18 years or older, proficient in English, will be recruited online via an audience recruitment platform. Participants are randomly assigned (1:1 ratio) to (1) the intervention group: three AI-assisted PLSs based on recent Cochrane reviews; or (2) the control group: three human-generated Cochrane PLSs. The primary outcome is comprehension (aligned with QUEST's Understanding dimension), assessed via a 10-item multiple-choice questionnaire for each summary, structured according to Cochrane PLS template sections. Secondary outcomes are readability, quality of information, safety considerations, and perceived trustworthiness. This study aims to provide insights into integrating AI technologies in health communication. Its findings will inform future practices in disseminating evidence-based health information to the public.</div></div>","PeriodicalId":51079,"journal":{"name":"Journal of Clinical Epidemiology","volume":"185 ","pages":"Article 111894"},"PeriodicalIF":5.2000,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Comparison of AI-assisted and human-generated plain language summaries for Cochrane reviews: protocol for a randomized trial (HIET-1)\",\"authors\":\"Declan Devane , Johanna Pope , Paula Byrne , Evan Forde , Steven Woloshin , Eileen Culloty , Darren Dahly , Ingeborg Hess Elgersma , Heather Munthe-Kaas , Conor Judge , Martin O'Donnell , Finn Krewer , Sandra Galvin , Nikita Burke , Theresa Tierney , KM Saif-Ur-Rahman , Tom Conway , James Thomas\",\"doi\":\"10.1016/j.jclinepi.2025.111894\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Plain language summaries (PLSs) of systematic reviews present complex health evidence in accessible language. Advances in artificial intelligence (AI), particularly large language models, may enhance the generation of PLSs. This protocol describes a randomized, parallel-group, two-armed, noninferiority trial comparing AI-assisted vs human-generated PLSs. Adults aged 18 years or older, proficient in English, will be recruited online via an audience recruitment platform. Participants are randomly assigned (1:1 ratio) to (1) the intervention group: three AI-assisted PLSs based on recent Cochrane reviews; or (2) the control group: three human-generated Cochrane PLSs. The primary outcome is comprehension (aligned with QUEST's Understanding dimension), assessed via a 10-item multiple-choice questionnaire for each summary, structured according to Cochrane PLS template sections. Secondary outcomes are readability, quality of information, safety considerations, and perceived trustworthiness. This study aims to provide insights into integrating AI technologies in health communication. Its findings will inform future practices in disseminating evidence-based health information to the public.</div></div>\",\"PeriodicalId\":51079,\"journal\":{\"name\":\"Journal of Clinical Epidemiology\",\"volume\":\"185 \",\"pages\":\"Article 111894\"},\"PeriodicalIF\":5.2000,\"publicationDate\":\"2025-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Clinical Epidemiology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0895435625002276\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"HEALTH CARE SCIENCES & SERVICES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Clinical Epidemiology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0895435625002276","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"HEALTH CARE SCIENCES & SERVICES","Score":null,"Total":0}
Comparison of AI-assisted and human-generated plain language summaries for Cochrane reviews: protocol for a randomized trial (HIET-1)
Plain language summaries (PLSs) of systematic reviews present complex health evidence in accessible language. Advances in artificial intelligence (AI), particularly large language models, may enhance the generation of PLSs. This protocol describes a randomized, parallel-group, two-armed, noninferiority trial comparing AI-assisted vs human-generated PLSs. Adults aged 18 years or older, proficient in English, will be recruited online via an audience recruitment platform. Participants are randomly assigned (1:1 ratio) to (1) the intervention group: three AI-assisted PLSs based on recent Cochrane reviews; or (2) the control group: three human-generated Cochrane PLSs. The primary outcome is comprehension (aligned with QUEST's Understanding dimension), assessed via a 10-item multiple-choice questionnaire for each summary, structured according to Cochrane PLS template sections. Secondary outcomes are readability, quality of information, safety considerations, and perceived trustworthiness. This study aims to provide insights into integrating AI technologies in health communication. Its findings will inform future practices in disseminating evidence-based health information to the public.
期刊介绍:
The Journal of Clinical Epidemiology strives to enhance the quality of clinical and patient-oriented healthcare research by advancing and applying innovative methods in conducting, presenting, synthesizing, disseminating, and translating research results into optimal clinical practice. Special emphasis is placed on training new generations of scientists and clinical practice leaders.