naa的事太麻烦了

IF 20.8 1区医学 Q1 ENDOCRINOLOGY & METABOLISM

Nature metabolism Pub Date : 2025-07-23 DOI:10.1038/s42255-025-01327-5

Jan-Bernd Funcke, Philipp E. Scherer

引用次数: 0

摘要

Felix等人最近在Nature Metabolism上发表的一项研究表明，脂肪细胞中由天冬氨酸酰化酶（Aspa编码）分解n -乙酰天冬氨酸（NAA）在调节循环NAA水平、维持系统葡萄糖稳态和控制餐后体温方面具有至关重要的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Much ado about NAA-thing

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Much ado about NAA-thing

A recent study in Nature Metabolism by Felix et al. reveals that the breakdown of N-acetylaspartate (NAA) by the enzyme aspartoacylase (encoded by Aspa) in adipocytes has a crucial role in regulating circulating NAA levels, maintaining systemic glucose homeostasis and controlling postprandial body temperature.

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来源期刊

Nature metabolism ENDOCRINOLOGY & METABOLISM-

CiteScore

27.50

自引率

2.40%

发文量

170

期刊介绍： Nature Metabolism is a peer-reviewed scientific journal that covers a broad range of topics in metabolism research. It aims to advance the understanding of metabolic and homeostatic processes at a cellular and physiological level. The journal publishes research from various fields, including fundamental cell biology, basic biomedical and translational research, and integrative physiology. It focuses on how cellular metabolism affects cellular function, the physiology and homeostasis of organs and tissues, and the regulation of organismal energy homeostasis. It also investigates the molecular pathophysiology of metabolic diseases such as diabetes and obesity, as well as their treatment. Nature Metabolism follows the standards of other Nature-branded journals, with a dedicated team of professional editors, rigorous peer-review process, high standards of copy-editing and production, swift publication, and editorial independence. The journal has a high impact factor, has a certain influence in the international area, and is deeply concerned and cited by the majority of scholars.