NAMPT和NNMT通过细胞外囊泡作为可溶性介质释放，是黑色素瘤细胞对BRAF抑制剂耐药影响肿瘤微环境的显著特征。

IF 8.2 2区生物学 Q1 CELL BIOLOGY

Cell Communication and Signaling Pub Date : 2025-07-21 DOI:10.1186/s12964-025-02361-2

Beatrice Ghezzi, Irene Fiorilla, Ágata Carreira, Francesco Recco, Leonardo Sorci, Lidia Avalle, Alessia Ponzano, Francesca Mazzola, Alberto Maria Todesco, Nicoletta Tommasi, Massimiliano Gasparrini, Vito Giuseppe D'Agostino, Flavio Mignone, Alessandro Provenzani, Valentina Audrito

引用次数: 0

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NAMPT and NNMT released via extracellular vesicles and as soluble mediators are distinguished traits of BRAF inhibitor resistance of melanoma cells impacting on the tumor microenvironment.

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来源期刊

Cell Communication and Signaling CELL BIOLOGY-

CiteScore

11.00

自引率

0.00%

发文量

180

期刊介绍： Cell Communication and Signaling (CCS) is a peer-reviewed, open-access scientific journal that focuses on cellular signaling pathways in both normal and pathological conditions. It publishes original research, reviews, and commentaries, welcoming studies that utilize molecular, morphological, biochemical, structural, and cell biology approaches. CCS also encourages interdisciplinary work and innovative models, including in silico, in vitro, and in vivo approaches, to facilitate investigations of cell signaling pathways, networks, and behavior. Starting from January 2019, CCS is proud to announce its affiliation with the International Cell Death Society. The journal now encourages submissions covering all aspects of cell death, including apoptotic and non-apoptotic mechanisms, cell death in model systems, autophagy, clearance of dying cells, and the immunological and pathological consequences of dying cells in the tissue microenvironment.