{"title":"妊娠期心包填塞及大量胸腔积液一例纵隔恶性畸胎瘤。","authors":"Kuky Cahya Hamurajib, Nurulita Ainun Alma, Meydita Fauzia Putri Insani, Diah Rumekti Hadiati","doi":"10.1007/s12055-025-01914-x","DOIUrl":null,"url":null,"abstract":"<p><p>Mediastinal teratomas are germ cell tumors which account for 8-13% of mediastinal masses. Early diagnosis of malignant teratoma is the key point of effective patient management. This report presents a rare case of a mediastinal malignant teratoma in a 38-year-old pregnant woman, complicated by cardiac tamponade and massive pleural effusion. The patient experienced dyspnea on exertion and orthopnea in her 29-week gestation. Thoracic magnetic resonance imaging revealed a tumor in the anterior mediastinal region which compressed the superior vena cava. Biopsy of the mass and analysis of the pericardial fluid showed the presence of malignant cells, and histopathological evaluation verified the diagnosis of malignant teratoma. The patient subsequently underwent neoadjuvant chemotherapy; however, the patient continued to experience persistent shortness of breath and the pregnancy was terminated at 33 weeks of gestation.</p>","PeriodicalId":13285,"journal":{"name":"Indian Journal of Thoracic and Cardiovascular Surgery","volume":"41 8","pages":"1055-1058"},"PeriodicalIF":0.6000,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12276162/pdf/","citationCount":"0","resultStr":"{\"title\":\"Cardiac tamponade and massive pleural effusion during pregnancy: a case of mediastinal malignant teratoma.\",\"authors\":\"Kuky Cahya Hamurajib, Nurulita Ainun Alma, Meydita Fauzia Putri Insani, Diah Rumekti Hadiati\",\"doi\":\"10.1007/s12055-025-01914-x\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Mediastinal teratomas are germ cell tumors which account for 8-13% of mediastinal masses. Early diagnosis of malignant teratoma is the key point of effective patient management. This report presents a rare case of a mediastinal malignant teratoma in a 38-year-old pregnant woman, complicated by cardiac tamponade and massive pleural effusion. The patient experienced dyspnea on exertion and orthopnea in her 29-week gestation. Thoracic magnetic resonance imaging revealed a tumor in the anterior mediastinal region which compressed the superior vena cava. Biopsy of the mass and analysis of the pericardial fluid showed the presence of malignant cells, and histopathological evaluation verified the diagnosis of malignant teratoma. The patient subsequently underwent neoadjuvant chemotherapy; however, the patient continued to experience persistent shortness of breath and the pregnancy was terminated at 33 weeks of gestation.</p>\",\"PeriodicalId\":13285,\"journal\":{\"name\":\"Indian Journal of Thoracic and Cardiovascular Surgery\",\"volume\":\"41 8\",\"pages\":\"1055-1058\"},\"PeriodicalIF\":0.6000,\"publicationDate\":\"2025-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12276162/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Indian Journal of Thoracic and Cardiovascular Surgery\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1007/s12055-025-01914-x\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/3/3 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q4\",\"JCRName\":\"CARDIAC & CARDIOVASCULAR SYSTEMS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Indian Journal of Thoracic and Cardiovascular Surgery","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s12055-025-01914-x","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/3/3 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
Cardiac tamponade and massive pleural effusion during pregnancy: a case of mediastinal malignant teratoma.
Mediastinal teratomas are germ cell tumors which account for 8-13% of mediastinal masses. Early diagnosis of malignant teratoma is the key point of effective patient management. This report presents a rare case of a mediastinal malignant teratoma in a 38-year-old pregnant woman, complicated by cardiac tamponade and massive pleural effusion. The patient experienced dyspnea on exertion and orthopnea in her 29-week gestation. Thoracic magnetic resonance imaging revealed a tumor in the anterior mediastinal region which compressed the superior vena cava. Biopsy of the mass and analysis of the pericardial fluid showed the presence of malignant cells, and histopathological evaluation verified the diagnosis of malignant teratoma. The patient subsequently underwent neoadjuvant chemotherapy; however, the patient continued to experience persistent shortness of breath and the pregnancy was terminated at 33 weeks of gestation.
期刊介绍：
The primary aim of the Indian Journal of Thoracic and Cardiovascular Surgery is education. The journal aims to dissipate current clinical practices and developments in the area of cardiovascular and thoracic surgery. This includes information on cardiovascular epidemiology, aetiopathogenesis, clinical manifestation etc. The journal accepts manuscripts from cardiovascular anaesthesia, cardiothoracic and vascular nursing and technology development and new/innovative products.The journal is the official publication of the Indian Association of Cardiovascular and Thoracic Surgeons which has a membership of over 1000 at present.DescriptionThe journal is the official organ of the Indian Association of Cardiovascular-Thoracic Surgeons. It was started in 1982 by Dr. Solomon Victor and ws being published twice a year up to 1996. From 2000 the editorial office moved to Delhi. From 2001 the journal was extended to quarterly and subsequently four issues annually have been printed out at time and regularly without fail. The journal receives manuscripts from members and non-members and cardiovascular surgeons. The manuscripts are peer reviewed by at least two or sometimes three or four reviewers who are on the panel. The manuscript process is now completely online. Funding the journal comes partially from the organization and from revenue generated by subscription and advertisement.
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