Zulaikha Beevi S , Vanitha L , Shoba B , K. Prabhu Chandran
{"title":"GShC-Net:基于DCTLAP特征提取的混合深度学习脑肿瘤检测","authors":"Zulaikha Beevi S , Vanitha L , Shoba B , K. Prabhu Chandran","doi":"10.1016/j.compbiolchem.2025.108577","DOIUrl":null,"url":null,"abstract":"<div><div>A brain tumor is an abnormal cell growth in a brain, which is not detected early. Initial detection of brain tumors is extremely critical for treatment planning as well as the survival of a patient. Brain tumors come in different forms, have unique properties, and require tailored therapies. Thus, detecting brain tumors physically is a laborious, complex, as well as error-prone process. Hence, an automated computer-assisted diagnosis with better correctness is presently in high demand. Here, this paper developed a hybrid GoogleNet-Shepard Convolutional Networks (GShC-Net) method that is employed for detecting brain tumors. The process of this approach is as illustrated follows. Firstly, an input image is carried out from the database that is given to a pre-processing module. After that, brain tumor segmentation is performed, as well as features such as Haralick texture features, Statistical features, and Discrete Cosine Transform with Local Arc Pattern (DCTLAP) are extracted. Finally, brain tumor is detected based on GShC-Net. Moreover, the GoogleNet and Shepard Convolutional Neural Networks (ShCNN) models are fused to create GShC-Net, in which the layers are modified. The proposed GShC-Net method effectively improves the early detection and classification of brain tumors, potentially aiding in more accurate and timely medical diagnoses. Furthermore, the GShC-Net is assessed by using True Positive Rate (TPR), True Negative Rate (TNR), as well as accuracy and the values attained are0.940, 0.930, and 0.932, respectively.</div></div>","PeriodicalId":10616,"journal":{"name":"Computational Biology and Chemistry","volume":"119 ","pages":"Article 108577"},"PeriodicalIF":3.1000,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"GShC-Net: Hybrid deep learning with DCTLAP feature extraction for brain tumor detection\",\"authors\":\"Zulaikha Beevi S , Vanitha L , Shoba B , K. Prabhu Chandran\",\"doi\":\"10.1016/j.compbiolchem.2025.108577\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>A brain tumor is an abnormal cell growth in a brain, which is not detected early. Initial detection of brain tumors is extremely critical for treatment planning as well as the survival of a patient. Brain tumors come in different forms, have unique properties, and require tailored therapies. Thus, detecting brain tumors physically is a laborious, complex, as well as error-prone process. Hence, an automated computer-assisted diagnosis with better correctness is presently in high demand. Here, this paper developed a hybrid GoogleNet-Shepard Convolutional Networks (GShC-Net) method that is employed for detecting brain tumors. The process of this approach is as illustrated follows. Firstly, an input image is carried out from the database that is given to a pre-processing module. After that, brain tumor segmentation is performed, as well as features such as Haralick texture features, Statistical features, and Discrete Cosine Transform with Local Arc Pattern (DCTLAP) are extracted. Finally, brain tumor is detected based on GShC-Net. Moreover, the GoogleNet and Shepard Convolutional Neural Networks (ShCNN) models are fused to create GShC-Net, in which the layers are modified. The proposed GShC-Net method effectively improves the early detection and classification of brain tumors, potentially aiding in more accurate and timely medical diagnoses. Furthermore, the GShC-Net is assessed by using True Positive Rate (TPR), True Negative Rate (TNR), as well as accuracy and the values attained are0.940, 0.930, and 0.932, respectively.</div></div>\",\"PeriodicalId\":10616,\"journal\":{\"name\":\"Computational Biology and Chemistry\",\"volume\":\"119 \",\"pages\":\"Article 108577\"},\"PeriodicalIF\":3.1000,\"publicationDate\":\"2025-07-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Computational Biology and Chemistry\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1476927125002385\",\"RegionNum\":4,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Computational Biology and Chemistry","FirstCategoryId":"99","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1476927125002385","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"BIOLOGY","Score":null,"Total":0}
GShC-Net: Hybrid deep learning with DCTLAP feature extraction for brain tumor detection
A brain tumor is an abnormal cell growth in a brain, which is not detected early. Initial detection of brain tumors is extremely critical for treatment planning as well as the survival of a patient. Brain tumors come in different forms, have unique properties, and require tailored therapies. Thus, detecting brain tumors physically is a laborious, complex, as well as error-prone process. Hence, an automated computer-assisted diagnosis with better correctness is presently in high demand. Here, this paper developed a hybrid GoogleNet-Shepard Convolutional Networks (GShC-Net) method that is employed for detecting brain tumors. The process of this approach is as illustrated follows. Firstly, an input image is carried out from the database that is given to a pre-processing module. After that, brain tumor segmentation is performed, as well as features such as Haralick texture features, Statistical features, and Discrete Cosine Transform with Local Arc Pattern (DCTLAP) are extracted. Finally, brain tumor is detected based on GShC-Net. Moreover, the GoogleNet and Shepard Convolutional Neural Networks (ShCNN) models are fused to create GShC-Net, in which the layers are modified. The proposed GShC-Net method effectively improves the early detection and classification of brain tumors, potentially aiding in more accurate and timely medical diagnoses. Furthermore, the GShC-Net is assessed by using True Positive Rate (TPR), True Negative Rate (TNR), as well as accuracy and the values attained are0.940, 0.930, and 0.932, respectively.
期刊介绍:
Computational Biology and Chemistry publishes original research papers and review articles in all areas of computational life sciences. High quality research contributions with a major computational component in the areas of nucleic acid and protein sequence research, molecular evolution, molecular genetics (functional genomics and proteomics), theory and practice of either biology-specific or chemical-biology-specific modeling, and structural biology of nucleic acids and proteins are particularly welcome. Exceptionally high quality research work in bioinformatics, systems biology, ecology, computational pharmacology, metabolism, biomedical engineering, epidemiology, and statistical genetics will also be considered.
Given their inherent uncertainty, protein modeling and molecular docking studies should be thoroughly validated. In the absence of experimental results for validation, the use of molecular dynamics simulations along with detailed free energy calculations, for example, should be used as complementary techniques to support the major conclusions. Submissions of premature modeling exercises without additional biological insights will not be considered.
Review articles will generally be commissioned by the editors and should not be submitted to the journal without explicit invitation. However prospective authors are welcome to send a brief (one to three pages) synopsis, which will be evaluated by the editors.