输尿管夹术治疗复杂双肾女童因异位输尿管伴肾功能不全引起的持续性尿滴:文献综述

IF 1.7 4区 医学 Q2 PEDIATRICS
Translational pediatrics Pub Date : 2025-06-27 Epub Date: 2025-06-25 DOI:10.21037/tp-2025-17
Giulia Lanfranchi, Irene Paraboschi, Guglielmo Mantica, Sara Costanzo, Giorgio Giuseppe Orlando Selvaggio, Manuel Lopez, Gloria Pelizzo
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引用次数: 0

摘要

背景和目的:女童双肾系统和异位输尿管起源于肾功能不全是一个复杂的儿科泌尿外科临床问题。与这些异常相关的尿失禁是社会困扰,通常难以保守管理。传统的手术选择,包括上极半肾切除术或输尿管输尿管造口术,是有效的,但可能与显著的手术发病率相关,特别是当肾功能可以忽略不计和手术进入具有挑战性时。近年来,微创输尿管结扎术——腹腔镜下或通过开放小切口——已成为切除或断开异位输尿管的一种有前景的低风险替代方法。这篇综述文章旨在批判性地评估输尿管结扎在这类儿科患者中的安全性、有效性和临床应用。方法:到2024年5月,通过PubMed和Web of Science进行全面的文献检索。关键词包括“输尿管夹断”、“输尿管结扎”、“异位输尿管”、“小儿尿失禁”。只考虑了涉及儿童人群的英语研究。排除标准包括重复出版物、动物研究和未报告临床结果的文章。两名独立审稿人进行了数据提取和综合,重点关注术后尿失禁、并发症、肾脏结局和手术细节。输尿管结扎与输尿管异位和上部部分无功能的女孩尿失禁的解决或显著改善一致相关。该手术在技术上似乎很简单,手术时间最短,术中出血量可以忽略不计。并发症发生率低,仅报道了一例后续症状性感染或剩余肾部分功能丧失。然而,现有的数据主要来自小型、回顾性、单中心系列,随访时间有限,缺乏对照组。结论:微创输尿管结扎术是输尿管异位引流功能不良肾段患者可行且有效的手术选择。更大的、多中心的前瞻性研究是有必要的,以确认其长期疗效,并为其更广泛的应用建立明确的临床指导方针。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Ureteral clipping for managing persistent urinary dribbling caused by ectopic ureters associated with non-functioning renal moieties in girls with complex duplex kidneys: a narrative review of the literature.

Ureteral clipping for managing persistent urinary dribbling caused by ectopic ureters associated with non-functioning renal moieties in girls with complex duplex kidneys: a narrative review of the literature.

Background and objective: Persistent urinary dribbling in girls with duplex renal systems and ectopic ureters originating from poorly functioning renal moieties represents a complex clinical problem in pediatric urology. The incontinence associated with these anomalies is socially distressing and often refractory to conservative management. Traditional surgical options, including upper pole heminephrectomy or ureteroureterostomy, are effective but may be associated with significant operative morbidity, particularly when renal function is negligible and surgical access is challenging. In recent years, minimally invasive ureteral ligation-either laparoscopic or via open mini-incision-has emerged as a promising, low-risk alternative to excise or disconnect the ectopic ureter. This review article aims to critically evaluate the safety, efficacy, and clinical utility of ureteral ligation in this subset of pediatric patients.

Methods: A comprehensive literature search was conducted using PubMed and Web of Science through May 2024. Keywords included "ureteral clipping", "ureteral ligation", "ectopic ureter", and "paediatric urinary incontinence". Only English-language studies involving human pediatric populations were considered. Exclusion criteria included duplicate publications, animal studies, and articles that did not report clinical outcomes. Two independent reviewers performed data extraction and synthesis, focusing on postoperative continence, complications, renal outcomes, and procedural details.

Key content and findings: Ureteral ligation was consistently associated with resolution or significant improvement of urinary incontinence in girls with ectopic ureters and non-functional upper moieties. The procedure appears to be technically straightforward, with minimal operative time and negligible intraoperative blood loss. Complication rates were low, and only one case of subsequent symptomatic infection or functional loss in the remaining renal moiety were reported. However, available data derive predominantly from small, retrospective, single-center series, with limited follow-up durations and the absence of control groups.

Conclusions: Minimally invasive ureteral ligation represents a viable and effective surgical option for selected patients with ectopic ureters draining poorly functioning renal segments. Larger, multicenter prospective studies are warranted to confirm its long-term efficacy and establish clear clinical guidelines for its broader adoption.

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来源期刊
Translational pediatrics
Translational pediatrics Medicine-Pediatrics, Perinatology and Child Health
CiteScore
4.50
自引率
5.00%
发文量
108
期刊介绍: Information not localized
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