Francesca Calderoni , Andrea D’Alessio , Marco Maria Jacopo Felisi , Klarisa Elena Szilagyi , Cristina De Mattia , Mariangela Piano , Emanuela Piccaluga , Alessandro Turra , Marco Brambilla , Paola Enrica Colombo
{"title":"神经放射学和血流动力学程序的有效和器官剂量评估:三种不同模拟软件的比较","authors":"Francesca Calderoni , Andrea D’Alessio , Marco Maria Jacopo Felisi , Klarisa Elena Szilagyi , Cristina De Mattia , Mariangela Piano , Emanuela Piccaluga , Alessandro Turra , Marco Brambilla , Paola Enrica Colombo","doi":"10.1016/j.ejmp.2025.105053","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><div>The goal of this work is to compare three different software for effective (ED) and organ (OD) dose estimation to analyze the reliability and investigate the main differences.</div></div><div><h3>Methods</h3><div>Both thirty neuroradiologic and hemodynamic procedures were analyzed retrospectively choosing a representative sample in terms of kerma-area product and complexity. Each procedure was simulated using NCIRF, VirtualDose-IR Batch Utility<!--> <!-->and PCXMC. The three software differ for computational method and phantom used and they also need different parameters from RDSR or experimental data to meet the requirements.<!--> <!-->Bland-Altman method was used to assess the agreement among software.</div></div><div><h3>Results</h3><div>Large variations in some ODs were observed for all the software, ranging from −70 % to 109 % for neuroradiology and −73 % to 92 % for hemodynamics. This variation is greatly reduced when considering ED, from −23 % to 19 % and from −12 % to 18 % respectively. Bland-Altman analysis showed a poor agreement in OD estimations, with mean differences from 0.8 to 92 mGy and variations up to 200 mGy. The variability in ED is less evident, with mean differences from 1.3 to 3.7 mSv for neuroradiology and from 0.6 mSv to 3.4 mSv for hemodynamics, although in individual cases these differences reached 7.6 mSv and 11 mSv respectively.</div></div><div><h3>Conclusions</h3><div>Differences principally arise from input parameters, models and phantoms which strongly affect ODs. Nevertheless, the overall EDs is confirmed to be a robust quantity with discrepancies lower than 4 mSv (20 %), showing differences comparable to uncertainties in radiological dosimetry and confirming its utility in population dose assessment.</div></div>","PeriodicalId":56092,"journal":{"name":"Physica Medica-European Journal of Medical Physics","volume":"136 ","pages":"Article 105053"},"PeriodicalIF":2.7000,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Effective and organ doses assessment in neuroradiologic and hemodynamic procedures: comparison among three different simulation software\",\"authors\":\"Francesca Calderoni , Andrea D’Alessio , Marco Maria Jacopo Felisi , Klarisa Elena Szilagyi , Cristina De Mattia , Mariangela Piano , Emanuela Piccaluga , Alessandro Turra , Marco Brambilla , Paola Enrica Colombo\",\"doi\":\"10.1016/j.ejmp.2025.105053\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Introduction</h3><div>The goal of this work is to compare three different software for effective (ED) and organ (OD) dose estimation to analyze the reliability and investigate the main differences.</div></div><div><h3>Methods</h3><div>Both thirty neuroradiologic and hemodynamic procedures were analyzed retrospectively choosing a representative sample in terms of kerma-area product and complexity. Each procedure was simulated using NCIRF, VirtualDose-IR Batch Utility<!--> <!-->and PCXMC. The three software differ for computational method and phantom used and they also need different parameters from RDSR or experimental data to meet the requirements.<!--> <!-->Bland-Altman method was used to assess the agreement among software.</div></div><div><h3>Results</h3><div>Large variations in some ODs were observed for all the software, ranging from −70 % to 109 % for neuroradiology and −73 % to 92 % for hemodynamics. This variation is greatly reduced when considering ED, from −23 % to 19 % and from −12 % to 18 % respectively. Bland-Altman analysis showed a poor agreement in OD estimations, with mean differences from 0.8 to 92 mGy and variations up to 200 mGy. The variability in ED is less evident, with mean differences from 1.3 to 3.7 mSv for neuroradiology and from 0.6 mSv to 3.4 mSv for hemodynamics, although in individual cases these differences reached 7.6 mSv and 11 mSv respectively.</div></div><div><h3>Conclusions</h3><div>Differences principally arise from input parameters, models and phantoms which strongly affect ODs. 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Effective and organ doses assessment in neuroradiologic and hemodynamic procedures: comparison among three different simulation software
Introduction
The goal of this work is to compare three different software for effective (ED) and organ (OD) dose estimation to analyze the reliability and investigate the main differences.
Methods
Both thirty neuroradiologic and hemodynamic procedures were analyzed retrospectively choosing a representative sample in terms of kerma-area product and complexity. Each procedure was simulated using NCIRF, VirtualDose-IR Batch Utility and PCXMC. The three software differ for computational method and phantom used and they also need different parameters from RDSR or experimental data to meet the requirements. Bland-Altman method was used to assess the agreement among software.
Results
Large variations in some ODs were observed for all the software, ranging from −70 % to 109 % for neuroradiology and −73 % to 92 % for hemodynamics. This variation is greatly reduced when considering ED, from −23 % to 19 % and from −12 % to 18 % respectively. Bland-Altman analysis showed a poor agreement in OD estimations, with mean differences from 0.8 to 92 mGy and variations up to 200 mGy. The variability in ED is less evident, with mean differences from 1.3 to 3.7 mSv for neuroradiology and from 0.6 mSv to 3.4 mSv for hemodynamics, although in individual cases these differences reached 7.6 mSv and 11 mSv respectively.
Conclusions
Differences principally arise from input parameters, models and phantoms which strongly affect ODs. Nevertheless, the overall EDs is confirmed to be a robust quantity with discrepancies lower than 4 mSv (20 %), showing differences comparable to uncertainties in radiological dosimetry and confirming its utility in population dose assessment.
期刊介绍:
Physica Medica, European Journal of Medical Physics, publishing with Elsevier from 2007, provides an international forum for research and reviews on the following main topics:
Medical Imaging
Radiation Therapy
Radiation Protection
Measuring Systems and Signal Processing
Education and training in Medical Physics
Professional issues in Medical Physics.