数字设计骨;一种针对严重青少年髋关节发育不良的3d患者特异性同种异体移植支架:从数字设计到临床现实-一个概念性病例报告。

IF 2.1 Q2 ORTHOPEDICS
Erik M van Bussel, Jafar Nasrabadi, Joëll Magré, Vahid Arbabi, Koen Willemsen, Bart J Kaptein, Bjorn P Meij, Marianna A Tryfonidou, Bart C H van der Wal, Harrie H Weinans, Ralph J B Sakkers
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引用次数: 0

摘要

背景:患有严重髋关节发育不良的青少年经常接受髋臼周围截骨术以预防疼痛和早期骨关节炎。不幸的是,这种手术不适合严重发育不良的髋关节不完全变形。最佳的治疗方法可能是对股骨覆盖进行量身定制的生物优化,使其形状与异常解剖结构相匹配。本研究介绍了一种基于个性化3D运动学规划的患者特异性同种异体移植支架增强的新方法。方法:17岁的严重右侧髋关节发育不良患者行3D CT分析,显示外侧中心边缘角为-7°,颅侧股骨头覆盖率为50%。使用数字增强技术和运动学模拟,在尊重运动范围的同时优化了股骨覆盖范围。在骨库中发现具有数字设计的匹配表面和曲率的远端股骨异体皮质架,并使用患者特异性模具植入髋臼边缘。结果:患者特异性同种异体骨架植入后,在保持活动范围的情况下,股骨头外侧中心边缘角和股骨头覆盖范围分别增加到18°和77%。随访9个月时的CT扫描显示同种异体移植物在原生骨中融合,并持续覆盖患者特异性同种异体移植物支架的承重区域。结论:数字化设计了一个髋臼增强架,并使用匹配的同种异体供体植入严重髋关节发育不良患者。良好和可预测的功能和放射学结果表明,患者特异性同种异体骨支架可能是严重髋关节发育不良青少年的一个重要选择。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Digitally Designed Bone; A 3D-patient-specific Allograft Shelf for Severe Adolescent Hip Dysplasia: From Digital Design to Clinical Reality-A Conceptual Case Report.

Digitally Designed Bone; A 3D-patient-specific Allograft Shelf for Severe Adolescent Hip Dysplasia: From Digital Design to Clinical Reality-A Conceptual Case Report.

Digitally Designed Bone; A 3D-patient-specific Allograft Shelf for Severe Adolescent Hip Dysplasia: From Digital Design to Clinical Reality-A Conceptual Case Report.

Digitally Designed Bone; A 3D-patient-specific Allograft Shelf for Severe Adolescent Hip Dysplasia: From Digital Design to Clinical Reality-A Conceptual Case Report.

Background: Adolescents with severe dysplasia of the hip regularly undergo a periacetabular osteotomy to prevent pain and early osteoarthritis. Unfortunately, this procedure is not suited for severe dysplasia with a non-congruent-deformed hip joint. The optimal treatment might be a tailor-made biologic optimization of femoral coverage with a shape matching the aberrant anatomy. This study introduces a novel approach using a patient-specific allograft shelf augmentation based on personalized 3D kinematic planning.

Methods: A 17-year-old patient with severe right-sided hip dysplasia underwent 3D CT analysis showing a lateral center-edge angle of -7° and a craniocaudal femoral head coverage of 50%. Using digital augmentation techniques and kinematic simulations, the femoral coverage was optimized while respecting the range of motion. An allograft cortical shelf of a distal femur with a matching surface and curvature as digitally designed was found in the bone bank and implanted at the acetabular rim using patient-specific molds.

Results: After uncomplicated implantation of the patient-specific allograft shelf, the lateral center-edge angle and femoral head coverage increased to 18° and 77% while preserving range of motion. A CT scan at 9-month follow-up showed incorporation of the allograft in the native bone with sustained coverage of the weight-bearing area of the patient-specific allograft shelf.

Conclusion: An acetabular augmentation shelf was digitally designed and implanted using a matching allograft donor in a case of severe hip dysplasia. The excellent and predictable functional and radiologic outcomes suggest that patient-specific allograft bone shelves could be a serious option for adolescents with severe hip dysplasia.

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来源期刊
CiteScore
2.60
自引率
6.70%
发文量
282
审稿时长
8 weeks
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