从常规PET/CT到长轴视场PET/CT过渡后[18F]FDG辐射剂量的回顾性比较

IF 2 4区 医学 Q3 ENGINEERING, BIOMEDICAL
Wei-Ting Jacky Chen, William I D Rae, Peter L Kench, Kathy P Willowson, Dale L Bailey, Elizabeth A Bailey, Heidi Fearnside, Eleanor Kelliher, Steven R Meikle
{"title":"从常规PET/CT到长轴视场PET/CT过渡后[18F]FDG辐射剂量的回顾性比较","authors":"Wei-Ting Jacky Chen, William I D Rae, Peter L Kench, Kathy P Willowson, Dale L Bailey, Elizabeth A Bailey, Heidi Fearnside, Eleanor Kelliher, Steven R Meikle","doi":"10.1007/s13246-025-01588-0","DOIUrl":null,"url":null,"abstract":"<p><p>Long axial field of view (LAFOV) PET/CT scanners (> 1 m axial FOV) provide an order of magnitude higher system sensitivity compared with conventional scanners. This creates opportunities for significant radiation dose reductions for patients, without loss of diagnostic image quality or increased scan time. This study aimed to investigate changes in radiation dose received by patients undergoing whole-body [<sup>18</sup>F]FDG PET/CT studies at a metropolitan hospital following the transition from the Siemens Biograph mCT (21.8 cm axial FOV) to the Siemens Biograph Vision Quadra LAFOV PET/CT (106 cm axial FOV). For the mCT and Quadra, 484 and 554 patient studies were reviewed, respectively. The radiation dose from the PET component was derived from the recorded FDG dose, calculated based on ICRP recommendations, and scaled to patient weight. The CT dose was derived from the dose-length product. The median effective dose from the PET component for the mCT and Quadra was 6.2 (IQR 5.5-6.9) and 2.9 (IQR 2.8-3.6) mSv, respectively, and 5.7 (IQR 5.1-6.5) and 2.8 (IQR 2.4-3.4) mSv, respectively, when scaled to patient weight. The median effective dose from the CT component for the mCT and Quadra was 7.7 (IQR 6.2-9.4) and 7.6 (IQR 5.9-9.4) mSv, respectively. The total median effective dose combining PET and CT components for the mCT and Quadra was 13.9 (IQR 12.4-15.7) and 10.5 (IQR 9.4-12.3) mSv, respectively, and 13.5 (IQR 12.4-15.0) and 10.3 (IQR 9.3-11.9) mSv, respectively, when scaled to patient weight. While the effective dose from PET was approximately halved due to reduced injected activity, the CT effective dose remained relatively unchanged and is now the dominant source of radiation dose to the patient for LAFOV PET/CT.</p>","PeriodicalId":48490,"journal":{"name":"Physical and Engineering Sciences in Medicine","volume":" ","pages":"1337-1349"},"PeriodicalIF":2.0000,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A retrospective comparison of [<sup>18</sup>F]FDG radiation dose following a transition from conventional to long axial field of view PET/CT.\",\"authors\":\"Wei-Ting Jacky Chen, William I D Rae, Peter L Kench, Kathy P Willowson, Dale L Bailey, Elizabeth A Bailey, Heidi Fearnside, Eleanor Kelliher, Steven R Meikle\",\"doi\":\"10.1007/s13246-025-01588-0\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Long axial field of view (LAFOV) PET/CT scanners (> 1 m axial FOV) provide an order of magnitude higher system sensitivity compared with conventional scanners. This creates opportunities for significant radiation dose reductions for patients, without loss of diagnostic image quality or increased scan time. This study aimed to investigate changes in radiation dose received by patients undergoing whole-body [<sup>18</sup>F]FDG PET/CT studies at a metropolitan hospital following the transition from the Siemens Biograph mCT (21.8 cm axial FOV) to the Siemens Biograph Vision Quadra LAFOV PET/CT (106 cm axial FOV). For the mCT and Quadra, 484 and 554 patient studies were reviewed, respectively. The radiation dose from the PET component was derived from the recorded FDG dose, calculated based on ICRP recommendations, and scaled to patient weight. The CT dose was derived from the dose-length product. The median effective dose from the PET component for the mCT and Quadra was 6.2 (IQR 5.5-6.9) and 2.9 (IQR 2.8-3.6) mSv, respectively, and 5.7 (IQR 5.1-6.5) and 2.8 (IQR 2.4-3.4) mSv, respectively, when scaled to patient weight. The median effective dose from the CT component for the mCT and Quadra was 7.7 (IQR 6.2-9.4) and 7.6 (IQR 5.9-9.4) mSv, respectively. The total median effective dose combining PET and CT components for the mCT and Quadra was 13.9 (IQR 12.4-15.7) and 10.5 (IQR 9.4-12.3) mSv, respectively, and 13.5 (IQR 12.4-15.0) and 10.3 (IQR 9.3-11.9) mSv, respectively, when scaled to patient weight. While the effective dose from PET was approximately halved due to reduced injected activity, the CT effective dose remained relatively unchanged and is now the dominant source of radiation dose to the patient for LAFOV PET/CT.</p>\",\"PeriodicalId\":48490,\"journal\":{\"name\":\"Physical and Engineering Sciences in Medicine\",\"volume\":\" \",\"pages\":\"1337-1349\"},\"PeriodicalIF\":2.0000,\"publicationDate\":\"2025-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Physical and Engineering Sciences in Medicine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s13246-025-01588-0\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/7/18 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"ENGINEERING, BIOMEDICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Physical and Engineering Sciences in Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s13246-025-01588-0","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/7/18 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
引用次数: 0

摘要

与传统扫描仪相比,长轴向视场(LAFOV) PET/CT扫描仪(> 1 m轴向视场)提供了更高的系统灵敏度。这为显著降低患者的辐射剂量创造了机会,而不会损失诊断图像质量或增加扫描时间。本研究旨在调查在一家大都市医院接受全身[18F]FDG PET/CT检查的患者从Siemens Biograph mCT (21.8 cm轴向FOV)过渡到Siemens Biograph Vision Quadra LAFOV PET/CT (106 cm轴向FOV)后所接受的辐射剂量变化。对于mCT和Quadra,分别回顾了484和554例患者研究。PET成分的辐射剂量来自于记录的FDG剂量,根据ICRP建议计算,并按患者体重比例计算。CT剂量由剂量-长度乘积得出。PET成分对mCT和Quadra的中位有效剂量分别为6.2 (IQR 5.5-6.9)和2.9 (IQR 2.8-3.6)毫西弗,按患者体重比例分别为5.7 (IQR 5.1-6.5)和2.8 (IQR 2.4-3.4)毫西弗。CT成分对mCT和Quadra的中位有效剂量分别为7.7 (IQR 6.2-9.4)和7.6 (IQR 5.9-9.4) mSv。mCT和Quadra的PET和CT组合成分的总中位有效剂量分别为13.9 (IQR 12.4-15.7)和10.5 (IQR 9.4-12.3) mSv,按患者体重比例分别为13.5 (IQR 12.4-15.0)和10.3 (IQR 9.3-11.9) mSv。由于注射活性降低,PET的有效剂量大约减半,而CT的有效剂量保持相对不变,目前是LAFOV PET/CT对患者的主要辐射剂量来源。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A retrospective comparison of [18F]FDG radiation dose following a transition from conventional to long axial field of view PET/CT.

Long axial field of view (LAFOV) PET/CT scanners (> 1 m axial FOV) provide an order of magnitude higher system sensitivity compared with conventional scanners. This creates opportunities for significant radiation dose reductions for patients, without loss of diagnostic image quality or increased scan time. This study aimed to investigate changes in radiation dose received by patients undergoing whole-body [18F]FDG PET/CT studies at a metropolitan hospital following the transition from the Siemens Biograph mCT (21.8 cm axial FOV) to the Siemens Biograph Vision Quadra LAFOV PET/CT (106 cm axial FOV). For the mCT and Quadra, 484 and 554 patient studies were reviewed, respectively. The radiation dose from the PET component was derived from the recorded FDG dose, calculated based on ICRP recommendations, and scaled to patient weight. The CT dose was derived from the dose-length product. The median effective dose from the PET component for the mCT and Quadra was 6.2 (IQR 5.5-6.9) and 2.9 (IQR 2.8-3.6) mSv, respectively, and 5.7 (IQR 5.1-6.5) and 2.8 (IQR 2.4-3.4) mSv, respectively, when scaled to patient weight. The median effective dose from the CT component for the mCT and Quadra was 7.7 (IQR 6.2-9.4) and 7.6 (IQR 5.9-9.4) mSv, respectively. The total median effective dose combining PET and CT components for the mCT and Quadra was 13.9 (IQR 12.4-15.7) and 10.5 (IQR 9.4-12.3) mSv, respectively, and 13.5 (IQR 12.4-15.0) and 10.3 (IQR 9.3-11.9) mSv, respectively, when scaled to patient weight. While the effective dose from PET was approximately halved due to reduced injected activity, the CT effective dose remained relatively unchanged and is now the dominant source of radiation dose to the patient for LAFOV PET/CT.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
8.40
自引率
4.50%
发文量
110
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信