{"title":"亨特教授与芬尼根公司的关系及其对质谱仪发展的影响。","authors":"Michael S Story, George C Stafford, John E P Syka","doi":"10.1016/j.mcpro.2025.101033","DOIUrl":null,"url":null,"abstract":"<p><p>Don Hunt's 50-year collaboration with Finnigan Instruments Corporation has resulted in many innovations in mass spectrometry that range from new instrumentation to new analytical methodologies which in turn enabled new applications. The fruits of this collaboration, directly and indirectly, have had a broad and enduring impact on the instrumentation and practice of modern mass spectrometry. The authors of this monograph were members of the research and development team at Finnigan over time frames that collectively encompass the entirety of the collaboration. This article provides a narrative history and chronology of the Hunt-Finnigan relationship based on their personal recollections as well as the recollections of other participants.</p>","PeriodicalId":18712,"journal":{"name":"Molecular & Cellular Proteomics","volume":" ","pages":"101033"},"PeriodicalIF":6.1000,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Professor D.F. Hunt relationship with Finnigan Corporation and His Impact on Mass Spectrometer Development.\",\"authors\":\"Michael S Story, George C Stafford, John E P Syka\",\"doi\":\"10.1016/j.mcpro.2025.101033\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Don Hunt's 50-year collaboration with Finnigan Instruments Corporation has resulted in many innovations in mass spectrometry that range from new instrumentation to new analytical methodologies which in turn enabled new applications. The fruits of this collaboration, directly and indirectly, have had a broad and enduring impact on the instrumentation and practice of modern mass spectrometry. The authors of this monograph were members of the research and development team at Finnigan over time frames that collectively encompass the entirety of the collaboration. This article provides a narrative history and chronology of the Hunt-Finnigan relationship based on their personal recollections as well as the recollections of other participants.</p>\",\"PeriodicalId\":18712,\"journal\":{\"name\":\"Molecular & Cellular Proteomics\",\"volume\":\" \",\"pages\":\"101033\"},\"PeriodicalIF\":6.1000,\"publicationDate\":\"2025-07-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Molecular & Cellular Proteomics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1016/j.mcpro.2025.101033\",\"RegionNum\":2,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"BIOCHEMICAL RESEARCH METHODS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Molecular & Cellular Proteomics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/j.mcpro.2025.101033","RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOCHEMICAL RESEARCH METHODS","Score":null,"Total":0}
Professor D.F. Hunt relationship with Finnigan Corporation and His Impact on Mass Spectrometer Development.
Don Hunt's 50-year collaboration with Finnigan Instruments Corporation has resulted in many innovations in mass spectrometry that range from new instrumentation to new analytical methodologies which in turn enabled new applications. The fruits of this collaboration, directly and indirectly, have had a broad and enduring impact on the instrumentation and practice of modern mass spectrometry. The authors of this monograph were members of the research and development team at Finnigan over time frames that collectively encompass the entirety of the collaboration. This article provides a narrative history and chronology of the Hunt-Finnigan relationship based on their personal recollections as well as the recollections of other participants.
期刊介绍:
The mission of MCP is to foster the development and applications of proteomics in both basic and translational research. MCP will publish manuscripts that report significant new biological or clinical discoveries underpinned by proteomic observations across all kingdoms of life. Manuscripts must define the biological roles played by the proteins investigated or their mechanisms of action.
The journal also emphasizes articles that describe innovative new computational methods and technological advancements that will enable future discoveries. Manuscripts describing such approaches do not have to include a solution to a biological problem, but must demonstrate that the technology works as described, is reproducible and is appropriate to uncover yet unknown protein/proteome function or properties using relevant model systems or publicly available data.
Scope:
-Fundamental studies in biology, including integrative "omics" studies, that provide mechanistic insights
-Novel experimental and computational technologies
-Proteogenomic data integration and analysis that enable greater understanding of physiology and disease processes
-Pathway and network analyses of signaling that focus on the roles of post-translational modifications
-Studies of proteome dynamics and quality controls, and their roles in disease
-Studies of evolutionary processes effecting proteome dynamics, quality and regulation
-Chemical proteomics, including mechanisms of drug action
-Proteomics of the immune system and antigen presentation/recognition
-Microbiome proteomics, host-microbe and host-pathogen interactions, and their roles in health and disease
-Clinical and translational studies of human diseases
-Metabolomics to understand functional connections between genes, proteins and phenotypes