电纺丝聚（乙烯醇）/硝酸银（PVA/AgNO₃）纳米纤维与间充质干细胞结合用于伤口敷料应用。

Q4 Biochemistry, Genetics and Molecular Biology

Methods in molecular biology Pub Date : 2025-07-17 DOI:10.1007/7651_2025_659

Aysegul Tiryaki, Ayse Ceren Calikoglu-Koyuncu

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引用次数: 0

摘要

本章介绍了一种新的方法，通过静电纺丝聚乙烯醇（PVA）和硝酸银（AgNO₃）的复合材料来开发抗菌伤口敷料。三维创面敷料将聚乙烯醇的生物相容性和良好的力学性能与银离子的抗菌性能相结合。静电纺丝工艺提供了结构的完整性和控制银离子的释放，以防止细菌感染。利用间充质干细胞（MSCs）评价电纺丝三维聚乙烯醇/AgNO3纳米纤维支架的生物相容性。

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Electrospun Poly(vinyl alcohol)/Silver Nitrate (PVA/AgNO₃) Nanofibers Incorporated with Mesenchymal Stem Cells for Wound Dressing Applications.

This chapter presents a novel approach for developing antibacterial wound dressings by electrospinning a composite of polyvinyl alcohol (PVA) and silver nitrate (AgNO₃). The three dimensional (3D) wound dressing combines the biocompatibility and favorable mechanical properties of PVA with the antibacterial properties of silver ions. The electrospinning process provides structural integrity and controlled release of silver ions to prevent bacterial infection. Mesenchymal stem cells (MSCs) are used to assess biocompatibility of electrospun 3D PVA/AgNO₃ nanofiber scaffolds for tissue engineering applications.

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来源期刊

Methods in molecular biology Biochemistry, Genetics and Molecular Biology-Genetics

CiteScore

2.00

自引率

0.00%

发文量

3536

期刊介绍： For over 20 years, biological scientists have come to rely on the research protocols and methodologies in the critically acclaimed Methods in Molecular Biology series. The series was the first to introduce the step-by-step protocols approach that has become the standard in all biomedical protocol publishing. Each protocol is provided in readily-reproducible step-by-step fashion, opening with an introductory overview, a list of the materials and reagents needed to complete the experiment, and followed by a detailed procedure that is supported with a helpful notes section offering tips and tricks of the trade as well as troubleshooting advice.