确保煎饼作为无蛋胃排空研究的替代食谱。

IF 1.3 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Nuclear Medicine Communications Pub Date : 2025-11-01 Epub Date: 2025-07-15 DOI:10.1097/MNM.0000000000002029
Andrea Blesa Jiménez, Nuria Olcina Forner, Carmen Belén Otero Alonso, Manuel Valiente Alarcón, María Teresa Martínez Martínez
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引用次数: 0

摘要

胃排空显像提供了一种生理的、无创的、定量的胃排空测量方法。共识指南推荐的标准化膳食包括一个鸡蛋替代品,相当于两个标有硫胶体([99mTc]Tc-SC)的全鸡蛋,两片面包,果酱和120毫升水。以前的研究报道了使用商业液体营养餐(LNM)作为鸡蛋过敏患者的合适膳食。我们的工作提出了一种基于将商用LNM烹饪成煎饼的替代配方,并评估了几种放射性药物在模拟胃介质中的结合稳定性,结论是[99mTc]Tc-MAA与LNM煎饼的结合率≥90%,类似于炒鸡蛋标准化餐,因此[99mTc]Tc-MAA-LNM煎饼可能是对鸡蛋过敏,LNM不耐受或难以完成整个标准餐的患者的良好替代方案。例如,对儿科病人来说,煎饼应该是一种有吸引力的食谱。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Ensure pancakes as an alternative recipe for egg-free gastric emptying studies.

Gastric emptying scintigraphy provides a physiologic, noninvasive, and quantitative measurement of gastric emptying. Consensus guidelines recommended a standardized meal that consisted of an egg substitute equal to two whole eggs labeled with sulphur colloid ([ 99m Tc]Tc-SC), two slices of bread, jam, and 120 mL of water. Previous studies reported the use of commercial liquid nutrient meal (LNM) as a suitable meal for patients with egg allergy. Our work proposes an alternative recipe based on cooking commercial LNM as a pancake, and evaluates the stability of binding of several radiopharmaceuticals in simulated gastric medium, concluding that [ 99m Tc]Tc-MAA binds to LNM pancakes in percentages ≥90%, similar to scrambled eggs standardized meal, so that [ 99m Tc]Tc-MAA-LNM in pancakes could be a good alternative for patients who have allergies to eggs, intolerance to LNM or difficulties for finishing the entire standard meal, as for instance pediatric patients for whom pancakes should be an attractive recipe.

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来源期刊
CiteScore
2.20
自引率
6.70%
发文量
212
审稿时长
3-8 weeks
期刊介绍: Nuclear Medicine Communications, the official journal of the British Nuclear Medicine Society, is a rapid communications journal covering nuclear medicine and molecular imaging with radionuclides, and the basic supporting sciences. As well as clinical research and commentary, manuscripts describing research on preclinical and basic sciences (radiochemistry, radiopharmacy, radiobiology, radiopharmacology, medical physics, computing and engineering, and technical and nursing professions involved in delivering nuclear medicine services) are welcomed, as the journal is intended to be of interest internationally to all members of the many medical and non-medical disciplines involved in nuclear medicine. In addition to papers reporting original studies, frankly written editorials and topical reviews are a regular feature of the journal.
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