中度青少年特发性脊柱侧凸的自然病程:一项平均25年随访研究。

IF 2.6 3区 医学 Q2 CLINICAL NEUROLOGY
Masayuki Ohashi, Kei Watanabe, Toru Hirano, Kazuhiro Hasegawa, Hideki Tashi, Keitaro Minato, Yohei Shibuya, Masayuki Sato, Mio Kubota, Hiroyuki Sekimoto, Hiroyuki Kawashima
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引用次数: 0

摘要

目的:本研究旨在确定中度青少年特发性脊柱侧凸(AIS)在曲线进展和健康相关生活质量(HRQOL)方面的自然病程。方法:纳入标准是非手术治疗的AIS患者,骨骼成熟度主要曲线在30°至40°之间(Risser≥4),调查时年龄≥30岁。纳入58例患者(女性55例),随访率为37.4%。骨骼成熟时的平均年龄为14.2岁,调查时的平均年龄为39.9岁,平均随访时间为25.7年。将HRQOL评分与年龄和性别匹配的健康志愿者(n = 112)进行比较。结果:骨骼成熟时主曲线的中位幅度为36.5°(n = 58), 18岁时为40°(n = 30),调查时为45.5°(n = 47),进展率为0.5°/年。46.7%的患者调查时主要曲线≥50°,其中82.4%的患者18岁时主要曲线≥40°。尽管他们的曲线进展,患者的HRQOL评分与对照组相当,除了SRS-22自我形象评分(AIS 2.8 vs.对照组3.4,p)。结论:中度AIS在整个成年期进展缓慢但显著。在平均25年的随访期间,超过40%的曲线为bbb50°。尽管骨骼成熟时患有中度AIS的成年患者的HRQOL评分与对照组相当,但他们的美容问题不容忽视。因此,中度曲线,特别是18岁左右≥40°的曲线,需要长期随访。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Natural course of moderate adolescent idiopathic scoliosis: a mean 25-year follow-up study.

Purpose: This study aimed to determine the natural course of moderate adolescent idiopathic scoliosis (AIS) in terms of curve progression and health-related quality of life (HRQOL).

Methods: The inclusion criteria were nonoperatively treated patients with AIS who had a major curve between 30° and 40° at skeletal maturity (Risser ≥ 4) and age ≥ 30 years at the survey. Fifty-eight patients (55 women) were included (follow-up rate, 37.4%). The mean age was 14.2 years at skeletal maturity and 39.9 years at the survey, with a mean 25.7-year follow-up. The HRQOL scores were compared with age- and sex-matched healthy volunteers (n = 112).

Results: The median magnitude of the major curve was 36.5° at skeletal maturity (n = 58), 40° at the age of 18 years (n = 30), and 45.5° at the survey (n = 47) with a progression rate of 0.5°/year. The major curve at the survey was over 50° in 46.7% of patients, 82.4% of whom had already had major curves ≥ 40° at the age of 18 years. Despite their curve progression, patients demonstrated comparable HRQOL scores with control participants, except for the SRS-22 self-image score (AIS 2.8 vs. Control 3.4, p < 0.001).

Conclusion: Moderate AIS progressed slowly but significantly throughout adulthood. Over 40% of the curves were > 50° during the mean 25-year follow-up period. Although the HRQOL scores of adult patients with moderate AIS at skeletal maturity were comparable with those of the controls, their cosmetic concerns could not be disregarded. Therefore, moderate curves, especially those ≥ 40° at the age approximately 18 years, warrant long-term follow-up.

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来源期刊
European Spine Journal
European Spine Journal 医学-临床神经学
CiteScore
4.80
自引率
10.70%
发文量
373
审稿时长
2-4 weeks
期刊介绍: "European Spine Journal" is a publication founded in response to the increasing trend toward specialization in spinal surgery and spinal pathology in general. The Journal is devoted to all spine related disciplines, including functional and surgical anatomy of the spine, biomechanics and pathophysiology, diagnostic procedures, and neurology, surgery and outcomes. The aim of "European Spine Journal" is to support the further development of highly innovative spine treatments including but not restricted to surgery and to provide an integrated and balanced view of diagnostic, research and treatment procedures as well as outcomes that will enhance effective collaboration among specialists worldwide. The “European Spine Journal” also participates in education by means of videos, interactive meetings and the endorsement of educative efforts. Official publication of EUROSPINE, The Spine Society of Europe
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