Weiguang Wang , Lijuan Ma , Wei Cai , Haiyan Zhao , Xia Zhang
{"title":"HMEA:融合多方面信息的层次化医学知识图谱实体对齐模型","authors":"Weiguang Wang , Lijuan Ma , Wei Cai , Haiyan Zhao , Xia Zhang","doi":"10.1016/j.artmed.2025.103188","DOIUrl":null,"url":null,"abstract":"<div><div>Medical entity alignment is crucial for the integration and reasoning of medical knowledge, aiming to match semantically equivalent entities across different medical knowledge graphs. Unlike entities in general knowledge graphs, medical entities contain rich multi-aspect information, which not only includes structural and attribute information but also additional information such as ontology and descriptions. However, existing entity alignment methods overlook these additional pieces of information and lack exploration into the fusion of multi-aspect information. This leads to less-than-ideal performance in medical entity alignment. To address the aforementioned issues, in this paper, we propose a hierarchical medical knowledge graph entity alignment method, termed HMEA, which integrates multi-aspect information. Firstly, we represent the medical knowledge graph as a hierarchical heterogeneous graph to model the multi-aspect information of medical entities. Secondly, we design different representation learning methods according to the characteristics of multi-aspect information to obtain vector representations of entities in different dimensions. Subsequently, we devise a two-stage multi-aspect knowledge fusion mechanism to dynamically integrate multi-aspect information, enabling mutual complementarity. Finally, we utilize the fused entity vector representations to guide entity alignment. We compare our approach with state-of-the-art baseline models on ten different types of publicly available datasets and further conduct ablation and parameter analyses. Experimental results validate the effectiveness and robustness of the proposed model. In benchmark tests across all datasets, HMEA outperforms the current state-of-the-art methods significantly.</div></div>","PeriodicalId":55458,"journal":{"name":"Artificial Intelligence in Medicine","volume":"168 ","pages":"Article 103188"},"PeriodicalIF":6.2000,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"HMEA: A hierarchical medical knowledge graph entity alignment model fusing multi-aspect information\",\"authors\":\"Weiguang Wang , Lijuan Ma , Wei Cai , Haiyan Zhao , Xia Zhang\",\"doi\":\"10.1016/j.artmed.2025.103188\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Medical entity alignment is crucial for the integration and reasoning of medical knowledge, aiming to match semantically equivalent entities across different medical knowledge graphs. Unlike entities in general knowledge graphs, medical entities contain rich multi-aspect information, which not only includes structural and attribute information but also additional information such as ontology and descriptions. However, existing entity alignment methods overlook these additional pieces of information and lack exploration into the fusion of multi-aspect information. This leads to less-than-ideal performance in medical entity alignment. To address the aforementioned issues, in this paper, we propose a hierarchical medical knowledge graph entity alignment method, termed HMEA, which integrates multi-aspect information. Firstly, we represent the medical knowledge graph as a hierarchical heterogeneous graph to model the multi-aspect information of medical entities. Secondly, we design different representation learning methods according to the characteristics of multi-aspect information to obtain vector representations of entities in different dimensions. Subsequently, we devise a two-stage multi-aspect knowledge fusion mechanism to dynamically integrate multi-aspect information, enabling mutual complementarity. Finally, we utilize the fused entity vector representations to guide entity alignment. We compare our approach with state-of-the-art baseline models on ten different types of publicly available datasets and further conduct ablation and parameter analyses. Experimental results validate the effectiveness and robustness of the proposed model. In benchmark tests across all datasets, HMEA outperforms the current state-of-the-art methods significantly.</div></div>\",\"PeriodicalId\":55458,\"journal\":{\"name\":\"Artificial Intelligence in Medicine\",\"volume\":\"168 \",\"pages\":\"Article 103188\"},\"PeriodicalIF\":6.2000,\"publicationDate\":\"2025-07-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Artificial Intelligence in Medicine\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S093336572500123X\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"COMPUTER SCIENCE, ARTIFICIAL INTELLIGENCE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Artificial Intelligence in Medicine","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S093336572500123X","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"COMPUTER SCIENCE, ARTIFICIAL INTELLIGENCE","Score":null,"Total":0}
HMEA: A hierarchical medical knowledge graph entity alignment model fusing multi-aspect information
Medical entity alignment is crucial for the integration and reasoning of medical knowledge, aiming to match semantically equivalent entities across different medical knowledge graphs. Unlike entities in general knowledge graphs, medical entities contain rich multi-aspect information, which not only includes structural and attribute information but also additional information such as ontology and descriptions. However, existing entity alignment methods overlook these additional pieces of information and lack exploration into the fusion of multi-aspect information. This leads to less-than-ideal performance in medical entity alignment. To address the aforementioned issues, in this paper, we propose a hierarchical medical knowledge graph entity alignment method, termed HMEA, which integrates multi-aspect information. Firstly, we represent the medical knowledge graph as a hierarchical heterogeneous graph to model the multi-aspect information of medical entities. Secondly, we design different representation learning methods according to the characteristics of multi-aspect information to obtain vector representations of entities in different dimensions. Subsequently, we devise a two-stage multi-aspect knowledge fusion mechanism to dynamically integrate multi-aspect information, enabling mutual complementarity. Finally, we utilize the fused entity vector representations to guide entity alignment. We compare our approach with state-of-the-art baseline models on ten different types of publicly available datasets and further conduct ablation and parameter analyses. Experimental results validate the effectiveness and robustness of the proposed model. In benchmark tests across all datasets, HMEA outperforms the current state-of-the-art methods significantly.
期刊介绍:
Artificial Intelligence in Medicine publishes original articles from a wide variety of interdisciplinary perspectives concerning the theory and practice of artificial intelligence (AI) in medicine, medically-oriented human biology, and health care.
Artificial intelligence in medicine may be characterized as the scientific discipline pertaining to research studies, projects, and applications that aim at supporting decision-based medical tasks through knowledge- and/or data-intensive computer-based solutions that ultimately support and improve the performance of a human care provider.