荧光黄催化的可见光驱动环丁酮肟烯丙基化：远端不饱和腈的可持续途径

IF 4.7 1区化学 Q1 CHEMISTRY, ORGANIC

Organic Chemistry Frontiers Pub Date : 2025-07-15 DOI:10.1039/d5qo00695c

Yanyu Lu, Kaiyu Yan, Yanzhe Shi, Cuiqing Gao, Yitao Zhu, Yinlei Zhang, Teck Peng Loh, Peizhong Xie

{"title":"荧光黄催化的可见光驱动环丁酮肟烯丙基化：远端不饱和腈的可持续途径","authors":"Yanyu Lu, Kaiyu Yan, Yanzhe Shi, Cuiqing Gao, Yitao Zhu, Yinlei Zhang, Teck Peng Loh, Peizhong Xie","doi":"10.1039/d5qo00695c","DOIUrl":null,"url":null,"abstract":"We present a naturally derived organophotoredox catalyst system for the ring-opening allylation of cyclobutanone O-acetyl oxime esters. This metal-free process operates under mild and environmentally benign conditions, demonstrating broad substrate compatibility. A range of distally unsaturated nitriles were synthesized in good to excellent yields with high stereoselectivity.","PeriodicalId":97,"journal":{"name":"Organic Chemistry Frontiers","volume":"109 1","pages":""},"PeriodicalIF":4.7000,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Lumiflavine-Catalyzed, Visible-Light-Driven Allylation of Cyclobutanone Oximes: A Sustainable Approach to Distally Unsaturated Nitriles\",\"authors\":\"Yanyu Lu, Kaiyu Yan, Yanzhe Shi, Cuiqing Gao, Yitao Zhu, Yinlei Zhang, Teck Peng Loh, Peizhong Xie\",\"doi\":\"10.1039/d5qo00695c\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"We present a naturally derived organophotoredox catalyst system for the ring-opening allylation of cyclobutanone O-acetyl oxime esters. This metal-free process operates under mild and environmentally benign conditions, demonstrating broad substrate compatibility. A range of distally unsaturated nitriles were synthesized in good to excellent yields with high stereoselectivity.\",\"PeriodicalId\":97,\"journal\":{\"name\":\"Organic Chemistry Frontiers\",\"volume\":\"109 1\",\"pages\":\"\"},\"PeriodicalIF\":4.7000,\"publicationDate\":\"2025-07-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Organic Chemistry Frontiers\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.1039/d5qo00695c\",\"RegionNum\":1,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, ORGANIC\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Organic Chemistry Frontiers","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1039/d5qo00695c","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}

引用次数: 0

摘要

我们提出了一种天然衍生的有机光氧化还原催化剂体系，用于环丁酮o -乙酰肟酯的开环烯丙基化。这种无金属工艺在温和和环境友好的条件下运行，显示出广泛的基材兼容性。合成了一系列具有高立体选择性的远端不饱和腈化合物。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Lumiflavine-Catalyzed, Visible-Light-Driven Allylation of Cyclobutanone Oximes: A Sustainable Approach to Distally Unsaturated Nitriles

We present a naturally derived organophotoredox catalyst system for the ring-opening allylation of cyclobutanone O-acetyl oxime esters. This metal-free process operates under mild and environmentally benign conditions, demonstrating broad substrate compatibility. A range of distally unsaturated nitriles were synthesized in good to excellent yields with high stereoselectivity.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Organic Chemistry Frontiers CHEMISTRY, ORGANIC-

CiteScore

7.90

自引率

11.10%

发文量

686

审稿时长

1 months

期刊介绍： Organic Chemistry Frontiers is an esteemed journal that publishes high-quality research across the field of organic chemistry. It places a significant emphasis on studies that contribute substantially to the field by introducing new or significantly improved protocols and methodologies. The journal covers a wide array of topics which include, but are not limited to, organic synthesis, the development of synthetic methodologies, catalysis, natural products, functional organic materials, supramolecular and macromolecular chemistry, as well as physical and computational organic chemistry.