卡塔普中毒并发阵发性室上性心动过速1例。

JNMA; journal of the Nepal Medical Association Pub Date : 2024-10-01 Epub Date: 2024-10-31 DOI:10.31729/jnma.8772
Newton Ashish Shah, Bibek Rajbhandari, Santosh Banstola, Manish Acharya, Rupesh Joshi, Shree Krishna Luitel, Manish Yadav
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引用次数: 0

摘要

卡塔普(Cartap)是一种从海洋环节动物异足蚓(Lumbriconeresis heteropoda)中提取的蛇毒毒素,被广泛用作杀虫剂,用于对付毛虫等害虫。虽然世界卫生组织将其列为中度危险,建议每日摄入量为0.05毫克/公斤,但人体毒性报告有限。一名34岁的女性在食用了一种未知的毒药后入院。她报告胃脘痛、灼烧感、出汗、呕吐、呼吸困难、心悸和不安,并伴有酒精摄入。最初因有机磷中毒治疗,她的胆碱酯酶水平为8.91。后来证实她摄入了100毫升浓度为50%的cartap。治疗包括胺碘酮治疗室上性心动过速,静脉注射n -乙酰半胱氨酸、硫酸镁和咪达唑仑治疗全局性强直性阵挛性发作。卡塔普因误食和皮肤接触而有毒,可引起呕吐、抽搐和室上性心动过速等心脏问题。支持性护理至关重要,认识到其风险是必要的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Cartap Poisoning with Paroxysmal Supraventricular Tachycardia: A Case Report.

Cartap, a nereistoxin derivative from the marine annelid Lumbriconeresis heteropoda, is widely used as a pesticide, targeting pests like caterpillars. While the WHO classifies it as moderately hazardous, with a recommended daily intake of 0.05 mg/kg, human toxicity reports are limited. A 34-year-old female was admitted after consuming an unknown poison. She reported epigastric pain, burning sensations, sweating, vomiting, dyspnea, palpitations, and restlessness, compounded by alcohol intake. Initially treated for organophosphate poisoning, her cholinesterase level was 8.91. It was later confirmed she ingested 100 ml of 50% concentration cartap. Treatment included amiodarone for supraventricular tachycardia and intravenous N-acetylcysteine, magnesium sulfate, and midazolam for general tonic clonic seizure. Cartap, toxic through ingestion and skin contact, can cause symptoms such as vomiting, convulsions, and cardiac issues like supraventricular tachycardia. Supportive care is crucial, and awareness of its risks is necessary.

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