Stephen Jaffee, Jyothika Mamagdi, Miriam Vaezi, Trent Kite, Bhavika Gupta, Samuel Valleta, Feno Monaco, Nestor Tomycz
{"title":"BurstDR™脊髓刺激治疗化疗诱导的周围神经病变。","authors":"Stephen Jaffee, Jyothika Mamagdi, Miriam Vaezi, Trent Kite, Bhavika Gupta, Samuel Valleta, Feno Monaco, Nestor Tomycz","doi":"10.25259/SNI_284_2025","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Chemotherapy-induced peripheral neuropathy (CIPN) is one of the most common persistent adverse effects of chemotherapy affecting cancer survivors. Other than the use of duloxetine, no other intervention has a proven benefit for these patients. Here, a patient with multiple myeloma who developed CIPN experienced a significant reduction in their symptoms after the implantation of a spinal cord stimulator.</p><p><strong>Case description: </strong>A 64-year-old male with a history of multiple myeloma presented with chronic pain 4 years after chemotherapy, followed by an autologous stem cell transplant. As the patient's symptoms were refractory to medical management, he underwent placement of a permanent spinal cord stimulator, resulting in 80% relief of calf pain and a 60% improvement in foot paresthesias/pain.</p><p><strong>Conclusion: </strong>Spinal cord stimulation proved effective in treating CIPN (CIPN following autologous stem cell transplant) in a 64-year-old male treated 4 years ago for multiple myeloma.</p>","PeriodicalId":94217,"journal":{"name":"Surgical neurology international","volume":"16 ","pages":"222"},"PeriodicalIF":0.0000,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12255184/pdf/","citationCount":"0","resultStr":"{\"title\":\"BurstDR™ spinal cord stimulation for chemotherapy-induced peripheral neuropathy.\",\"authors\":\"Stephen Jaffee, Jyothika Mamagdi, Miriam Vaezi, Trent Kite, Bhavika Gupta, Samuel Valleta, Feno Monaco, Nestor Tomycz\",\"doi\":\"10.25259/SNI_284_2025\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Chemotherapy-induced peripheral neuropathy (CIPN) is one of the most common persistent adverse effects of chemotherapy affecting cancer survivors. Other than the use of duloxetine, no other intervention has a proven benefit for these patients. Here, a patient with multiple myeloma who developed CIPN experienced a significant reduction in their symptoms after the implantation of a spinal cord stimulator.</p><p><strong>Case description: </strong>A 64-year-old male with a history of multiple myeloma presented with chronic pain 4 years after chemotherapy, followed by an autologous stem cell transplant. As the patient's symptoms were refractory to medical management, he underwent placement of a permanent spinal cord stimulator, resulting in 80% relief of calf pain and a 60% improvement in foot paresthesias/pain.</p><p><strong>Conclusion: </strong>Spinal cord stimulation proved effective in treating CIPN (CIPN following autologous stem cell transplant) in a 64-year-old male treated 4 years ago for multiple myeloma.</p>\",\"PeriodicalId\":94217,\"journal\":{\"name\":\"Surgical neurology international\",\"volume\":\"16 \",\"pages\":\"222\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-06-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12255184/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Surgical neurology international\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.25259/SNI_284_2025\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Surgical neurology international","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.25259/SNI_284_2025","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
BurstDR™ spinal cord stimulation for chemotherapy-induced peripheral neuropathy.
Background: Chemotherapy-induced peripheral neuropathy (CIPN) is one of the most common persistent adverse effects of chemotherapy affecting cancer survivors. Other than the use of duloxetine, no other intervention has a proven benefit for these patients. Here, a patient with multiple myeloma who developed CIPN experienced a significant reduction in their symptoms after the implantation of a spinal cord stimulator.
Case description: A 64-year-old male with a history of multiple myeloma presented with chronic pain 4 years after chemotherapy, followed by an autologous stem cell transplant. As the patient's symptoms were refractory to medical management, he underwent placement of a permanent spinal cord stimulator, resulting in 80% relief of calf pain and a 60% improvement in foot paresthesias/pain.
Conclusion: Spinal cord stimulation proved effective in treating CIPN (CIPN following autologous stem cell transplant) in a 64-year-old male treated 4 years ago for multiple myeloma.
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