Hidenori Tanaka, Toshio Kuwai, Shinji Nagata, Naoki Asayama, Yuko Hiraga, Tomohiko Kohno, Yuzuru Tamaru, Masaki Kunihiro, Koki Nakamura, Ken Yamashita, Yoshihiro Kishida, Shiro Oka
{"title":"内镜下粘膜剥离术治疗内痔的有效性：一项回顾性队列研究。","authors":"Hidenori Tanaka, Toshio Kuwai, Shinji Nagata, Naoki Asayama, Yuko Hiraga, Tomohiko Kohno, Yuzuru Tamaru, Masaki Kunihiro, Koki Nakamura, Ken Yamashita, Yoshihiro Kishida, Shiro Oka","doi":"10.1177/17562848251355710","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Improvement in internal hemorrhoids is frequently observed after endoscopic submucosal dissection (ESD) for rectal intraepithelial neoplasia. This study investigated the effectiveness of rectal ESD in the management of internal hemorrhoids.</p><p><strong>Objectives: </strong>Twenty-three patients who underwent ESD for tumors adjacent to the dentate line and associated with internal hemorrhoids.</p><p><strong>Design: </strong>A single-arm, retrospective multi-center study.</p><p><strong>Methods: </strong>The focal improvement (at the scarring area after ESD) and complete improvement rates of hemorrhoids at follow-up colonoscopies were evaluated.</p><p><strong>Results: </strong>Most patients (87%) had mild hemorrhoids. The focal and complete improvement rates of hemorrhoids were 83% and 48%, respectively. Complete improvement rates were 75% (3/4), 42% (5/12), and 43% (3/7) for tumors involving ⩾1/2, between 1/4 and 1/2, and <1/4 of the circumference at the dentate line, respectively. No recurrence was observed after initial improvement, with a median observation period of 35 months.</p><p><strong>Conclusion: </strong>ESD may be an effective treatment for internal hemorrhoids.</p>","PeriodicalId":48770,"journal":{"name":"Therapeutic Advances in Gastroenterology","volume":"18 ","pages":"17562848251355710"},"PeriodicalIF":3.9000,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12254673/pdf/","citationCount":"0","resultStr":"{\"title\":\"Effectiveness of endoscopic submucosal dissection in the management of internal hemorrhoids: a retrospective cohort study.\",\"authors\":\"Hidenori Tanaka, Toshio Kuwai, Shinji Nagata, Naoki Asayama, Yuko Hiraga, Tomohiko Kohno, Yuzuru Tamaru, Masaki Kunihiro, Koki Nakamura, Ken Yamashita, Yoshihiro Kishida, Shiro Oka\",\"doi\":\"10.1177/17562848251355710\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Improvement in internal hemorrhoids is frequently observed after endoscopic submucosal dissection (ESD) for rectal intraepithelial neoplasia. This study investigated the effectiveness of rectal ESD in the management of internal hemorrhoids.</p><p><strong>Objectives: </strong>Twenty-three patients who underwent ESD for tumors adjacent to the dentate line and associated with internal hemorrhoids.</p><p><strong>Design: </strong>A single-arm, retrospective multi-center study.</p><p><strong>Methods: </strong>The focal improvement (at the scarring area after ESD) and complete improvement rates of hemorrhoids at follow-up colonoscopies were evaluated.</p><p><strong>Results: </strong>Most patients (87%) had mild hemorrhoids. The focal and complete improvement rates of hemorrhoids were 83% and 48%, respectively. Complete improvement rates were 75% (3/4), 42% (5/12), and 43% (3/7) for tumors involving ⩾1/2, between 1/4 and 1/2, and <1/4 of the circumference at the dentate line, respectively. No recurrence was observed after initial improvement, with a median observation period of 35 months.</p><p><strong>Conclusion: </strong>ESD may be an effective treatment for internal hemorrhoids.</p>\",\"PeriodicalId\":48770,\"journal\":{\"name\":\"Therapeutic Advances in Gastroenterology\",\"volume\":\"18 \",\"pages\":\"17562848251355710\"},\"PeriodicalIF\":3.9000,\"publicationDate\":\"2025-07-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12254673/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Therapeutic Advances in Gastroenterology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1177/17562848251355710\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q1\",\"JCRName\":\"GASTROENTEROLOGY & HEPATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Therapeutic Advances in Gastroenterology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/17562848251355710","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q1","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}
Effectiveness of endoscopic submucosal dissection in the management of internal hemorrhoids: a retrospective cohort study.
Background: Improvement in internal hemorrhoids is frequently observed after endoscopic submucosal dissection (ESD) for rectal intraepithelial neoplasia. This study investigated the effectiveness of rectal ESD in the management of internal hemorrhoids.
Objectives: Twenty-three patients who underwent ESD for tumors adjacent to the dentate line and associated with internal hemorrhoids.
Design: A single-arm, retrospective multi-center study.
Methods: The focal improvement (at the scarring area after ESD) and complete improvement rates of hemorrhoids at follow-up colonoscopies were evaluated.
Results: Most patients (87%) had mild hemorrhoids. The focal and complete improvement rates of hemorrhoids were 83% and 48%, respectively. Complete improvement rates were 75% (3/4), 42% (5/12), and 43% (3/7) for tumors involving ⩾1/2, between 1/4 and 1/2, and <1/4 of the circumference at the dentate line, respectively. No recurrence was observed after initial improvement, with a median observation period of 35 months.
Conclusion: ESD may be an effective treatment for internal hemorrhoids.
期刊介绍：
Therapeutic Advances in Gastroenterology is an open access journal which delivers the highest quality peer-reviewed original research articles, reviews, and scholarly comment on pioneering efforts and innovative studies in the medical treatment of gastrointestinal and hepatic disorders. The journal has a strong clinical and pharmacological focus and is aimed at an international audience of clinicians and researchers in gastroenterology and related disciplines, providing an online forum for rapid dissemination of recent research and perspectives in this area.
The editors welcome original research articles across all areas of gastroenterology and hepatology.
The journal publishes original research articles and review articles primarily. Original research manuscripts may include laboratory, animal or human/clinical studies – all phases. Letters to the Editor and Case Reports will also be considered.
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