Adam N Musick, Robert K Wagner, Kameron M Kraus, Wyatt G S Southall, Austin T Gregg, Thomas J Policicchio, Maaz Muhammad, Stephen T Duncan, David C Landy, Arun Aneja
{"title":"新一代逆行股内钉远端互锁螺钉后撤。","authors":"Adam N Musick, Robert K Wagner, Kameron M Kraus, Wyatt G S Southall, Austin T Gregg, Thomas J Policicchio, Maaz Muhammad, Stephen T Duncan, David C Landy, Arun Aneja","doi":"10.1097/BOT.0000000000003043","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>To compare distal interlocking screw backout rates between two new-generation retrograde femoral nails: the DePuy Synthes RFN-Advanced Retrograde Femoral Nail (RFNA) and the Stryker T2 Alpha Femur Retrograde Nail (T2 Alpha).</p><p><strong>Methods: </strong>Design: Retrospective comparative study.</p><p><strong>Setting: </strong>Three Level 1 Trauma Centers.</p><p><strong>Patient selection criteria: </strong>Patients aged ≥18 years who underwent operative fixation with the RFNA or T2 Alpha for a diaphyseal or distal femur fracture (OTA/AO 32-33) between November 2022 and August 2024 with a minimum follow-up of 3 months.</p><p><strong>Outcome measures and comparisons: </strong>The primary outcome was the distal interlocking screw backout rate. Secondary outcomes included time to backout and reoperation rates for screw removal. Outcomes were compared between the RFNA and T2 Alpha.</p><p><strong>Results: </strong>A total of 103 patients (median age 59 years [IQR: 38-73], 61% female) were included, comprising 63 OTA/AO 32 and 40 OTA/AO 33 fractures, with 24 treated with the RFNA and 79 with the T2 Alpha. Backout rates were higher in the RFNA group (38% [95% CI: 20-59%] vs. 5.1% [95% CI: 1.6-13%], p<0.001). Stratified by fracture location, backout rates remained higher in the RFNA group for both diaphyseal (6/20 [30%] vs. 1/43 [2.3%], p=0.003) and metaphyseal fractures (3/4 [75%] vs. 3/36 [8.3%], p=0.008). Time to backout was earlier in the RFNA group (5 weeks [IQR: 3-6] vs. 19 weeks [IQR: 14-31], p=0.013). Reoperation rates for screw removal were higher in the RFNA group (21% vs. 0%, p<0.001). The median follow-up for the overall cohort was 27 weeks (IQR: 18-41).</p><p><strong>Conclusions: </strong>The RFNA was associated with a higher rate of distal interlocking screw backout, an earlier time to backout, and an increased reoperation rate for screw removal compared to the T2 Alpha. These findings can guide surgeons in implant selection and highlight the need for solutions to mitigate distal interlocking screw backout in the RFNA.</p><p><strong>Level of evidence: </strong>Therapeutic Level III.</p>","PeriodicalId":16644,"journal":{"name":"Journal of Orthopaedic Trauma","volume":" ","pages":""},"PeriodicalIF":1.6000,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Distal Interlocking Screw Backout in New-Generation Retrograde Femoral Nails.\",\"authors\":\"Adam N Musick, Robert K Wagner, Kameron M Kraus, Wyatt G S Southall, Austin T Gregg, Thomas J Policicchio, Maaz Muhammad, Stephen T Duncan, David C Landy, Arun Aneja\",\"doi\":\"10.1097/BOT.0000000000003043\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objectives: </strong>To compare distal interlocking screw backout rates between two new-generation retrograde femoral nails: the DePuy Synthes RFN-Advanced Retrograde Femoral Nail (RFNA) and the Stryker T2 Alpha Femur Retrograde Nail (T2 Alpha).</p><p><strong>Methods: </strong>Design: Retrospective comparative study.</p><p><strong>Setting: </strong>Three Level 1 Trauma Centers.</p><p><strong>Patient selection criteria: </strong>Patients aged ≥18 years who underwent operative fixation with the RFNA or T2 Alpha for a diaphyseal or distal femur fracture (OTA/AO 32-33) between November 2022 and August 2024 with a minimum follow-up of 3 months.</p><p><strong>Outcome measures and comparisons: </strong>The primary outcome was the distal interlocking screw backout rate. Secondary outcomes included time to backout and reoperation rates for screw removal. Outcomes were compared between the RFNA and T2 Alpha.</p><p><strong>Results: </strong>A total of 103 patients (median age 59 years [IQR: 38-73], 61% female) were included, comprising 63 OTA/AO 32 and 40 OTA/AO 33 fractures, with 24 treated with the RFNA and 79 with the T2 Alpha. Backout rates were higher in the RFNA group (38% [95% CI: 20-59%] vs. 5.1% [95% CI: 1.6-13%], p<0.001). Stratified by fracture location, backout rates remained higher in the RFNA group for both diaphyseal (6/20 [30%] vs. 1/43 [2.3%], p=0.003) and metaphyseal fractures (3/4 [75%] vs. 3/36 [8.3%], p=0.008). Time to backout was earlier in the RFNA group (5 weeks [IQR: 3-6] vs. 19 weeks [IQR: 14-31], p=0.013). Reoperation rates for screw removal were higher in the RFNA group (21% vs. 0%, p<0.001). The median follow-up for the overall cohort was 27 weeks (IQR: 18-41).</p><p><strong>Conclusions: </strong>The RFNA was associated with a higher rate of distal interlocking screw backout, an earlier time to backout, and an increased reoperation rate for screw removal compared to the T2 Alpha. These findings can guide surgeons in implant selection and highlight the need for solutions to mitigate distal interlocking screw backout in the RFNA.</p><p><strong>Level of evidence: </strong>Therapeutic Level III.</p>\",\"PeriodicalId\":16644,\"journal\":{\"name\":\"Journal of Orthopaedic Trauma\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.6000,\"publicationDate\":\"2025-07-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Orthopaedic Trauma\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1097/BOT.0000000000003043\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"ORTHOPEDICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Orthopaedic Trauma","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/BOT.0000000000003043","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ORTHOPEDICS","Score":null,"Total":0}
Distal Interlocking Screw Backout in New-Generation Retrograde Femoral Nails.
Objectives: To compare distal interlocking screw backout rates between two new-generation retrograde femoral nails: the DePuy Synthes RFN-Advanced Retrograde Femoral Nail (RFNA) and the Stryker T2 Alpha Femur Retrograde Nail (T2 Alpha).
Methods: Design: Retrospective comparative study.
Setting: Three Level 1 Trauma Centers.
Patient selection criteria: Patients aged ≥18 years who underwent operative fixation with the RFNA or T2 Alpha for a diaphyseal or distal femur fracture (OTA/AO 32-33) between November 2022 and August 2024 with a minimum follow-up of 3 months.
Outcome measures and comparisons: The primary outcome was the distal interlocking screw backout rate. Secondary outcomes included time to backout and reoperation rates for screw removal. Outcomes were compared between the RFNA and T2 Alpha.
Results: A total of 103 patients (median age 59 years [IQR: 38-73], 61% female) were included, comprising 63 OTA/AO 32 and 40 OTA/AO 33 fractures, with 24 treated with the RFNA and 79 with the T2 Alpha. Backout rates were higher in the RFNA group (38% [95% CI: 20-59%] vs. 5.1% [95% CI: 1.6-13%], p<0.001). Stratified by fracture location, backout rates remained higher in the RFNA group for both diaphyseal (6/20 [30%] vs. 1/43 [2.3%], p=0.003) and metaphyseal fractures (3/4 [75%] vs. 3/36 [8.3%], p=0.008). Time to backout was earlier in the RFNA group (5 weeks [IQR: 3-6] vs. 19 weeks [IQR: 14-31], p=0.013). Reoperation rates for screw removal were higher in the RFNA group (21% vs. 0%, p<0.001). The median follow-up for the overall cohort was 27 weeks (IQR: 18-41).
Conclusions: The RFNA was associated with a higher rate of distal interlocking screw backout, an earlier time to backout, and an increased reoperation rate for screw removal compared to the T2 Alpha. These findings can guide surgeons in implant selection and highlight the need for solutions to mitigate distal interlocking screw backout in the RFNA.
期刊介绍：
Journal of Orthopaedic Trauma is devoted exclusively to the diagnosis and management of hard and soft tissue trauma, including injuries to bone, muscle, ligament, and tendons, as well as spinal cord injuries. Under the guidance of a distinguished international board of editors, the journal provides the most current information on diagnostic techniques, new and improved surgical instruments and procedures, surgical implants and prosthetic devices, bioplastics and biometals; and physical therapy and rehabilitation.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
