Julie B Pajaniaye, Peter Alsing, Martin G Stisen, Erzsébet Horváth-Puhó, Maaike G J Gademan, Alma B Pedersen, Inger Mechlenburg Mechlenburg
{"title":"原发性膝关节置换术后体重指数与恢复工作之间的关系:一项基于人群的队列研究,来自丹麦国家登记的6128名患者。","authors":"Julie B Pajaniaye, Peter Alsing, Martin G Stisen, Erzsébet Horváth-Puhó, Maaike G J Gademan, Alma B Pedersen, Inger Mechlenburg Mechlenburg","doi":"10.2340/17453674.2025.44253","DOIUrl":null,"url":null,"abstract":"<p><strong>Background and purpose: </strong> With more knee arthroplasties (KAs) performed in working-age patients, interest in return to work (RTW) increases. We aimed to investigate the association between body mass index (BMI) and RTW after primary KA and whether the association varies by sex, age, comorbidity, and socioeconomic position.</p><p><strong>Methods: </strong> From Danish national registries, we included 6,128 patients aged 18 to 60 years undergoing KA from 2008-2018. Exposure was BMI in categories < 25.0, 25.0-29.9, 30.0-34.9, 35.0-39.9, and ≥ 40.0. Outcome was RTW after KA. We estimated cumulative incidence proportions (CIP) of RTW. Cox regression was used to calculate hazard ratios (HRs) with 95% confidence intervals (CI).</p><p><strong>Results: </strong> Median time to RTW was 70 days. Overall CIP for RTW was 63% (CI 62-65) at 3 months. With BMI < 25 as reference, CIP was 65% (n = 1,401) for BMI 25.0-29.9, 64% (n = 1,130) for BMI 30.0-34.9, 60% (n = 528) for BMI 35.0-39.9, and 60% (n = 260) for BMI ≥ 40.0, corresponding to an adjusted HR of 1.06 (CI 0.98-1.15), 1.02 (CI 0.94-1.11), 0.97 (CI 0.88-1.06), and 0.96 (CI 0.85-1.08). Men with BMI 35.0-39.9 and ≥ 40 had an adjusted HR of 0.89 (CI 0.76-1.05) and 0.87 (CI 0.70-1.10). None of the associations were statistically significant. Age, comorbidity, and socioeconomic position did not modify the association between BMI and RTW.</p><p><strong>Conclusion: </strong> More than 60% of patients RTW within 3 months but we found no association between BMI and RTW after primary KA.</p>","PeriodicalId":6916,"journal":{"name":"Acta Orthopaedica","volume":"96 ","pages":"529-536"},"PeriodicalIF":2.5000,"publicationDate":"2025-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12257360/pdf/","citationCount":"0","resultStr":"{\"title\":\"Association between body mass index and return to work following primary knee arthroplasty: a population-based cohort study on 6,128 patients from Danish national registers.\",\"authors\":\"Julie B Pajaniaye, Peter Alsing, Martin G Stisen, Erzsébet Horváth-Puhó, Maaike G J Gademan, Alma B Pedersen, Inger Mechlenburg Mechlenburg\",\"doi\":\"10.2340/17453674.2025.44253\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background and purpose: </strong> With more knee arthroplasties (KAs) performed in working-age patients, interest in return to work (RTW) increases. We aimed to investigate the association between body mass index (BMI) and RTW after primary KA and whether the association varies by sex, age, comorbidity, and socioeconomic position.</p><p><strong>Methods: </strong> From Danish national registries, we included 6,128 patients aged 18 to 60 years undergoing KA from 2008-2018. Exposure was BMI in categories < 25.0, 25.0-29.9, 30.0-34.9, 35.0-39.9, and ≥ 40.0. Outcome was RTW after KA. We estimated cumulative incidence proportions (CIP) of RTW. Cox regression was used to calculate hazard ratios (HRs) with 95% confidence intervals (CI).</p><p><strong>Results: </strong> Median time to RTW was 70 days. Overall CIP for RTW was 63% (CI 62-65) at 3 months. With BMI < 25 as reference, CIP was 65% (n = 1,401) for BMI 25.0-29.9, 64% (n = 1,130) for BMI 30.0-34.9, 60% (n = 528) for BMI 35.0-39.9, and 60% (n = 260) for BMI ≥ 40.0, corresponding to an adjusted HR of 1.06 (CI 0.98-1.15), 1.02 (CI 0.94-1.11), 0.97 (CI 0.88-1.06), and 0.96 (CI 0.85-1.08). Men with BMI 35.0-39.9 and ≥ 40 had an adjusted HR of 0.89 (CI 0.76-1.05) and 0.87 (CI 0.70-1.10). None of the associations were statistically significant. Age, comorbidity, and socioeconomic position did not modify the association between BMI and RTW.</p><p><strong>Conclusion: </strong> More than 60% of patients RTW within 3 months but we found no association between BMI and RTW after primary KA.</p>\",\"PeriodicalId\":6916,\"journal\":{\"name\":\"Acta Orthopaedica\",\"volume\":\"96 \",\"pages\":\"529-536\"},\"PeriodicalIF\":2.5000,\"publicationDate\":\"2025-07-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12257360/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Acta Orthopaedica\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.2340/17453674.2025.44253\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"ORTHOPEDICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta Orthopaedica","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.2340/17453674.2025.44253","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ORTHOPEDICS","Score":null,"Total":0}
Association between body mass index and return to work following primary knee arthroplasty: a population-based cohort study on 6,128 patients from Danish national registers.
Background and purpose: With more knee arthroplasties (KAs) performed in working-age patients, interest in return to work (RTW) increases. We aimed to investigate the association between body mass index (BMI) and RTW after primary KA and whether the association varies by sex, age, comorbidity, and socioeconomic position.
Methods: From Danish national registries, we included 6,128 patients aged 18 to 60 years undergoing KA from 2008-2018. Exposure was BMI in categories < 25.0, 25.0-29.9, 30.0-34.9, 35.0-39.9, and ≥ 40.0. Outcome was RTW after KA. We estimated cumulative incidence proportions (CIP) of RTW. Cox regression was used to calculate hazard ratios (HRs) with 95% confidence intervals (CI).
Results: Median time to RTW was 70 days. Overall CIP for RTW was 63% (CI 62-65) at 3 months. With BMI < 25 as reference, CIP was 65% (n = 1,401) for BMI 25.0-29.9, 64% (n = 1,130) for BMI 30.0-34.9, 60% (n = 528) for BMI 35.0-39.9, and 60% (n = 260) for BMI ≥ 40.0, corresponding to an adjusted HR of 1.06 (CI 0.98-1.15), 1.02 (CI 0.94-1.11), 0.97 (CI 0.88-1.06), and 0.96 (CI 0.85-1.08). Men with BMI 35.0-39.9 and ≥ 40 had an adjusted HR of 0.89 (CI 0.76-1.05) and 0.87 (CI 0.70-1.10). None of the associations were statistically significant. Age, comorbidity, and socioeconomic position did not modify the association between BMI and RTW.
Conclusion: More than 60% of patients RTW within 3 months but we found no association between BMI and RTW after primary KA.
期刊介绍:
Acta Orthopaedica (previously Acta Orthopaedica Scandinavica) presents original articles of basic research interest, as well as clinical studies in the field of orthopedics and related sub disciplines. Ever since the journal was founded in 1930, by a group of Scandinavian orthopedic surgeons, the journal has been published for an international audience. Acta Orthopaedica is owned by the Nordic Orthopaedic Federation and is the official publication of this federation.