Wuji Sun, Chao Ge, Yinghua Shi, Xiaohe He, Li Xiao, Yanfang Liu, Zhi Wang, Tianlong Ji, Huidong Wang
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The performance of the EPID was assessed for sensitivity to errors in monitor units, collimator angle, field offset, field size, and multi-leaf collimator functionality. Treatment plans were modified for each error and verified to determine the capability of the system to detect perturbations from the planned dose distribution, which was quantitatively analyzed using γ index analysis (2%/2 mm, 10% low-dose threshold). Additionally, the ArcCHECK phantom was employed to validate the EPID system for PSQA and induced error detection. Pearson's correlation coefficient was employed to assess correlations between γ passing rates and induced errors.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>The EPID system showed high accuracy in dose linearity and error detection, with γ passing rates consistently above 95% for original plans. Sensitivity tests indicated strong correlations between induced errors and γ passing rates, confirming the capability of this system to detect subtle dosimetric discrepancies and supporting its application for PSQA. Both EPID and ArcCHECK demonstrated comparable γ passing rates in PSQA of standardized plans and treatment plans, with EPID showing higher or comparable sensitivity to tested errors.</p>\n </section>\n \n <section>\n \n <h3> Conclusion</h3>\n \n <p>The EPID Plan QA system showed promising accuracy and sensitivity in detecting errors, proving to be a reliable tool for PSQA. Its seamless integration into clinical workflows is expected to enhance treatment verification efficiency and ensure precise radiotherapy delivery.</p>\n </section>\n </div>","PeriodicalId":14989,"journal":{"name":"Journal of Applied Clinical Medical Physics","volume":"26 7","pages":""},"PeriodicalIF":2.2000,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/acm2.70178","citationCount":"0","resultStr":"{\"title\":\"Evaluation of a Monte Carlo based EPID system for patient-specific IMRT and VMAT quality assurance\",\"authors\":\"Wuji Sun, Chao Ge, Yinghua Shi, Xiaohe He, Li Xiao, Yanfang Liu, Zhi Wang, Tianlong Ji, Huidong Wang\",\"doi\":\"10.1002/acm2.70178\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Purpose</h3>\\n \\n <p>This study aims to evaluate the performance of a new electronic portal imaging device (EPID) system with a Monte Carlo (MC) based algorithm for patient-specific quality assurance (PSQA), ensuring its reliability and effectiveness in treatment verification efficiency and precision.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Methods</h3>\\n \\n <p>Sixteen patients with various tumor sites were divided evenly into two groups for dynamic intensity-modulated radiation therapy and volumetric modulated arc therapy verification. Measurements were performed on a UIH uRT-linac 506c linear accelerator with a Varex Imaging XRD 1642 EPID. The performance of the EPID was assessed for sensitivity to errors in monitor units, collimator angle, field offset, field size, and multi-leaf collimator functionality. Treatment plans were modified for each error and verified to determine the capability of the system to detect perturbations from the planned dose distribution, which was quantitatively analyzed using γ index analysis (2%/2 mm, 10% low-dose threshold). Additionally, the ArcCHECK phantom was employed to validate the EPID system for PSQA and induced error detection. Pearson's correlation coefficient was employed to assess correlations between γ passing rates and induced errors.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>The EPID system showed high accuracy in dose linearity and error detection, with γ passing rates consistently above 95% for original plans. Sensitivity tests indicated strong correlations between induced errors and γ passing rates, confirming the capability of this system to detect subtle dosimetric discrepancies and supporting its application for PSQA. Both EPID and ArcCHECK demonstrated comparable γ passing rates in PSQA of standardized plans and treatment plans, with EPID showing higher or comparable sensitivity to tested errors.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusion</h3>\\n \\n <p>The EPID Plan QA system showed promising accuracy and sensitivity in detecting errors, proving to be a reliable tool for PSQA. 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Evaluation of a Monte Carlo based EPID system for patient-specific IMRT and VMAT quality assurance
Purpose
This study aims to evaluate the performance of a new electronic portal imaging device (EPID) system with a Monte Carlo (MC) based algorithm for patient-specific quality assurance (PSQA), ensuring its reliability and effectiveness in treatment verification efficiency and precision.
Methods
Sixteen patients with various tumor sites were divided evenly into two groups for dynamic intensity-modulated radiation therapy and volumetric modulated arc therapy verification. Measurements were performed on a UIH uRT-linac 506c linear accelerator with a Varex Imaging XRD 1642 EPID. The performance of the EPID was assessed for sensitivity to errors in monitor units, collimator angle, field offset, field size, and multi-leaf collimator functionality. Treatment plans were modified for each error and verified to determine the capability of the system to detect perturbations from the planned dose distribution, which was quantitatively analyzed using γ index analysis (2%/2 mm, 10% low-dose threshold). Additionally, the ArcCHECK phantom was employed to validate the EPID system for PSQA and induced error detection. Pearson's correlation coefficient was employed to assess correlations between γ passing rates and induced errors.
Results
The EPID system showed high accuracy in dose linearity and error detection, with γ passing rates consistently above 95% for original plans. Sensitivity tests indicated strong correlations between induced errors and γ passing rates, confirming the capability of this system to detect subtle dosimetric discrepancies and supporting its application for PSQA. Both EPID and ArcCHECK demonstrated comparable γ passing rates in PSQA of standardized plans and treatment plans, with EPID showing higher or comparable sensitivity to tested errors.
Conclusion
The EPID Plan QA system showed promising accuracy and sensitivity in detecting errors, proving to be a reliable tool for PSQA. Its seamless integration into clinical workflows is expected to enhance treatment verification efficiency and ensure precise radiotherapy delivery.
期刊介绍：
Journal of Applied Clinical Medical Physics is an international Open Access publication dedicated to clinical medical physics. JACMP welcomes original contributions dealing with all aspects of medical physics from scientists working in the clinical medical physics around the world. JACMP accepts only online submission.
JACMP will publish:
-Original Contributions: Peer-reviewed, investigations that represent new and significant contributions to the field. Recommended word count: up to 7500.
-Review Articles: Reviews of major areas or sub-areas in the field of clinical medical physics. These articles may be of any length and are peer reviewed.
-Technical Notes: These should be no longer than 3000 words, including key references.
-Letters to the Editor: Comments on papers published in JACMP or on any other matters of interest to clinical medical physics. These should not be more than 1250 (including the literature) and their publication is only based on the decision of the editor, who occasionally asks experts on the merit of the contents.
-Book Reviews: The editorial office solicits Book Reviews.
-Announcements of Forthcoming Meetings: The Editor may provide notice of forthcoming meetings, course offerings, and other events relevant to clinical medical physics.
-Parallel Opposed Editorial: We welcome topics relevant to clinical practice and medical physics profession. The contents can be controversial debate or opposed aspects of an issue. One author argues for the position and the other against. Each side of the debate contains an opening statement up to 800 words, followed by a rebuttal up to 500 words. Readers interested in participating in this series should contact the moderator with a proposed title and a short description of the topic
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