放射投影检查中基于病人大小的剂量优化:一种bmi引导方法

IF 2.2 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Sachith Welarathna, Sivakumar Velautham, Sivananthan Sarasanandarajah
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引用次数: 0

摘要

肥胖症的日益流行对投影摄影剂量优化提出了挑战,因为世界范围内超重和肥胖患者的解剖厚度更大。单独的诊断参考水平(drl)可能不能充分解释身体习惯的变化,可能导致患者保护不理想。本研究旨在探索基于患者身体质量指数(BMI)的斯里兰卡主要解剖区域放射投影检查的基准剂量(bmd),为剂量优化和drl提供一种补充方法。方法本前瞻性研究纳入1989例(≥18岁)在6家三级医院接受腹前位(AP)、胸后位(PA)、肾-输尿管-膀胱(KUB)、腰椎前位(AP)、腰椎侧位(LAT)和骨盆前位检查的成人患者。对于每次检查,记录患者的人口统计数据(年龄、体重、身高和BMI)和暴露参数(千伏电压峰值[kVp]和管电流暴露时间积[mAs]),并使用PKA计测量以kerma面积积(PKA)表示的患者剂量。drl(可达到的剂量)是在标准体型患者组(58±20 kg)的各医院PKA中位数分布的中位数提出的。对于基于BMI的bmd,将患者分为四种标准BMI类别:体重过轻、体重正常、超重和肥胖。各医院的中位PKA分布用于制定基于bmi的bmd,然后将其与标准尺寸患者组的建议drl进行比较。结果显示,在所有研究的BMI类别中,基于BMI的bmd逐渐增加。体重过轻、正常、超重和肥胖患者基于bmi的bmd(单位:Gy.cm2)分别为:1.46、1.94、2.88、3.00(腹部AP);0.17、0.21、0.22、0.25(胸部PA);1.70, 1.76, 2.30, 3.60 (kub ap);1.00, 1.03, 1.29, 1.48(腰椎AP);1.94, 2.09, 2.57, 2.56(腰椎LAT);骨盆AP分别为0.60、1.85、1.86、2.24。与体重正常的患者相比,体重过轻的患者在腹部AP、KUB AP、腰椎AP、腰椎LAT、胸部PA和骨盆AP的bmi基础骨密度分别下降了24.7%、3.4%、2.9%、7.1%、4.5%和67.6%。相反,在相同的检查中,超重患者的百分比分别增加了48.5%、30.7%、25.2%、23.0%、4.8%和0.5%,而肥胖患者的百分比分别增加了54.6%、104.5%、51.5%、22.5%、19.0%和21.1%。标准尺寸患者组的drl分别为1.82、0.22、2.03、1.27、2.21和1.90 Gy。分别平方厘米。这些发现强调了基于bmi的bmd作为个性化剂量优化的有效工具的重要性,考虑了患者身体体质的变化。将它们与drl一起纳入临床实践,可以加强对患者的保护并促进良好的放射学实践。此外,研究结果强调需要在BMI间隔引入国际drl指南,以确保在各国标准化实施。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Patient-size based dose optimization in projection radiography examinations: A BMI-guided approach

Patient-size based dose optimization in projection radiography examinations: A BMI-guided approach

Purpose

The increasing prevalence of obesity poses challenges for dose optimization in projection radiography due to greater anatomical thickness in overweight and obese patients worldwide. Diagnostic reference levels (DRLs) alone may not adequately account for variations in body habitus, potentially leading to suboptimal patient protection. This study aimed to explore benchmark doses (BMDs) based on patient body mass index (BMI) for projection radiography examinations of major anatomical regions in Sri Lanka, providing a complementary approach for dose optimization alongside DRLs.

Methods

This prospective study included 1989 adult patients (≥18 years) undergoing abdomen anteroposterior (AP), chest posteroanterior (PA), kidney–ureter–bladder (KUB) AP, lumbar spine AP, lumbar spine lateral (LAT), and pelvis AP examinations at six major tertiary care hospitals. For each examination, patient demographics (age, weight, height, and BMI) and exposure parameters (kilovoltage peak [kVp] and tube current-exposure time product [mAs]) were recorded, and the patient doses in terms of kerma-area product (PKA) were measured using a PKA meter. DRLs (achievable doses) were proposed at the median of the median PKA distribution across hospitals for a standard-sized patient group (58 ± 20 kg). For BMI-based BMDs, patients were classified into four standard BMI categories: underweight, normal weight, overweight, and obese. The median PKA distributions across hospitals were used to formulate BMI-based BMDs, which were then compared with the proposed DRLs for the standard-sized patient group.

Results

The results showed a progressive increase in BMI-based BMDs across BMI categories for all examinations studied. BMI-based BMDs (in Gy.cm2) for underweight, normal weight, overweight, and obese patients were as follows: 1.46, 1.94, 2.88, 3.00 (abdomen AP); 0.17, 0.21, 0.22, 0.25 (chest PA); 1.70, 1.76, 2.30, 3.60 (KUB AP); 1.00, 1.03, 1.29, 1.48 (lumbar spine AP); 1.94, 2.09, 2.57, 2.56 (lumbar spine LAT); and 0.60, 1.85, 1.86, 2.24 (pelvis AP). Compared to normal weight patients, underweight patients exhibited percentage reductions in BMI-based BMDs of 24.7%, 3.4%, 2.9%, 7.1%, 4.5%, and 67.6% for abdomen AP, KUB AP, lumbar spine AP, lumbar spine LAT, chest PA, and pelvis AP, respectively. Conversely, overweight patients demonstrated percentage increases of 48.5%, 30.7%, 25.2%, 23.0%, 4.8%, and 0.5% across the same examinations, while obese patients showed increases of 54.6%, 104.5%, 51.5%, 22.5%, 19.0%, and 21.1%, respectively. DRLs for the standard-sized patient group were 1.82, 0.22, 2.03, 1.27, 2.21, and 1.90 Gy.cm2, respectively.

Conclusion

These findings underscore the importance of BMI-based BMDs as an effective tool for personalized dose optimization, accounting for variations in patient body habitus. Their integration into clinical practice, alongside DRLs, could enhance patient protection and promote good radiographic practices. Furthermore, the findings underscore the need for the introduction of international guidelines for DRLs in intervals of BMI to ensure standardized implementation across countries.

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来源期刊
CiteScore
3.60
自引率
19.00%
发文量
331
审稿时长
3 months
期刊介绍: Journal of Applied Clinical Medical Physics is an international Open Access publication dedicated to clinical medical physics. JACMP welcomes original contributions dealing with all aspects of medical physics from scientists working in the clinical medical physics around the world. JACMP accepts only online submission. JACMP will publish: -Original Contributions: Peer-reviewed, investigations that represent new and significant contributions to the field. Recommended word count: up to 7500. -Review Articles: Reviews of major areas or sub-areas in the field of clinical medical physics. These articles may be of any length and are peer reviewed. -Technical Notes: These should be no longer than 3000 words, including key references. -Letters to the Editor: Comments on papers published in JACMP or on any other matters of interest to clinical medical physics. These should not be more than 1250 (including the literature) and their publication is only based on the decision of the editor, who occasionally asks experts on the merit of the contents. -Book Reviews: The editorial office solicits Book Reviews. -Announcements of Forthcoming Meetings: The Editor may provide notice of forthcoming meetings, course offerings, and other events relevant to clinical medical physics. -Parallel Opposed Editorial: We welcome topics relevant to clinical practice and medical physics profession. The contents can be controversial debate or opposed aspects of an issue. One author argues for the position and the other against. Each side of the debate contains an opening statement up to 800 words, followed by a rebuttal up to 500 words. Readers interested in participating in this series should contact the moderator with a proposed title and a short description of the topic
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