纳武单抗引起的舌头变色：1例报告。

IF 2.7 4区医学 Q3 IMMUNOLOGY

Immunotherapy Pub Date : 2025-07-13 DOI:10.1080/1750743X.2025.2533105

Elif Değirmenci Aktaş, Dilek Yildirim

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引用次数: 0

摘要

目前，免疫检查点抑制剂被用于卵巢癌的治疗。免疫治疗药物偶尔会引起以轻度红斑和黄斑丘疹为特征的皮肤反应的发展，通常涉及身体的躯干和四肢，偶尔可能出现瘙痒。特别是在使用抗pd -1（纳武单抗和派姆单抗）治疗剂中。在这个病例报告中，我们提出了一个病人，在卵巢癌患者纳武单抗治疗后出现舌毒性变色。舌头变色，这是免疫治疗的罕见副作用之一，以及可能与之相关的因素在本病例中进行了讨论。

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Nivolumab induced discolouration of the tongue: a case report.

Currently, immune checkpoint inhibitors are used in the treatment of ovarian cancer. Immunotherapy agents occasionally cause the development of skin reactions characterized by mild erythematous and maculopapular rashes, usually involving the trunk and extremities of the body, which may occasionally present with pruritus. It is especially seen in the use of anti-PD-1 (nivolumab and pembrolizumab) treatment agents. In this case report, we present a patient who developed discoloration of the tongue toxicity after nivolumab treatment in ovarian cancer patients. Discoloration of the tongue, which is one of the rare side effects of immunotherapy, and factors that may be associated with it are discussed in this case.

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来源期刊

Immunotherapy 医学-免疫学

CiteScore

5.00

自引率

3.60%

发文量

113

审稿时长

6-12 weeks

期刊介绍： Many aspects of the immune system and mechanisms of immunomodulatory therapies remain to be elucidated in order to exploit fully the emerging opportunities. Those involved in the research and clinical applications of immunotherapy are challenged by the huge and intricate volumes of knowledge arising from this fast-evolving field. The journal Immunotherapy offers the scientific community an interdisciplinary forum, providing them with information on the most recent advances of various aspects of immunotherapies, in a concise format to aid navigation of this complex field. Immunotherapy delivers essential information in concise, at-a-glance article formats. Key advances in the field are reported and analyzed by international experts, providing an authoritative but accessible forum for this vitally important area of research. Unsolicited article proposals are welcomed and authors are required to comply fully with the journal''s Disclosure & Conflict of Interest Policy as well as major publishing guidelines, including ICMJE and GPP3.