通过亲核芳香族取代钨氮配合物从二氮合成（杂）苯胺。

IF 14.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Journal of the American Chemical Society Pub Date : 2025-07-11 DOI:10.1021/jacs.5c06407

Lukas Eberle, Joachim Ballmann

{"title":"通过亲核芳香族取代钨氮配合物从二氮合成（杂）苯胺。","authors":"Lukas Eberle, Joachim Ballmann","doi":"10.1021/jacs.5c06407","DOIUrl":null,"url":null,"abstract":"A protocol for the arylation of both N atoms in dinitrogen is presented. This protocol relies on the use of tungsten pincer complexes to split N2 and generate tungsten nitrides, which were shown to undergo nucleophilic aromatic substitution (SNAr) reactions with electron-deficient aryl chlorides. Starting from (15N)2, this two-step process was exploited for the preparation of different 15N-labeled aryl amines.","PeriodicalId":49,"journal":{"name":"Journal of the American Chemical Society","volume":" ","pages":""},"PeriodicalIF":14.4000,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"(Hetero)anilines from Dinitrogen Via Nucleophilic Aromatic Substitution at Tungsten Nitrido Complexes.\",\"authors\":\"Lukas Eberle, Joachim Ballmann\",\"doi\":\"10.1021/jacs.5c06407\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A protocol for the arylation of both N atoms in dinitrogen is presented. This protocol relies on the use of tungsten pincer complexes to split N2 and generate tungsten nitrides, which were shown to undergo nucleophilic aromatic substitution (SNAr) reactions with electron-deficient aryl chlorides. Starting from (15N)2, this two-step process was exploited for the preparation of different 15N-labeled aryl amines.\",\"PeriodicalId\":49,\"journal\":{\"name\":\"Journal of the American Chemical Society\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":14.4000,\"publicationDate\":\"2025-07-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of the American Chemical Society\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.1021/jacs.5c06407\",\"RegionNum\":1,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of the American Chemical Society","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1021/jacs.5c06407","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}

引用次数: 0

摘要

提出了二氮中两个N原子的芳基化反应方案。该方案依赖于使用钨钳配合物分裂N2和生成氮化钨，其被证明与缺电子芳酰氯发生亲核芳香取代（SNAr）反应。从（15N）2开始，利用这两步法制备了不同的15N标记芳基胺。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

(Hetero)anilines from Dinitrogen Via Nucleophilic Aromatic Substitution at Tungsten Nitrido Complexes.

A protocol for the arylation of both N atoms in dinitrogen is presented. This protocol relies on the use of tungsten pincer complexes to split N₂ and generate tungsten nitrides, which were shown to undergo nucleophilic aromatic substitution (S_NAr) reactions with electron-deficient aryl chlorides. Starting from (¹⁵N)₂, this two-step process was exploited for the preparation of different ¹⁵N-labeled aryl amines.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Journal of the American Chemical Society 化学-化学综合

CiteScore

24.40

自引率

6.00%

发文量

2398

审稿时长

1.6 months

期刊介绍： The flagship journal of the American Chemical Society, known as the Journal of the American Chemical Society (JACS), has been a prestigious publication since its establishment in 1879. It holds a preeminent position in the field of chemistry and related interdisciplinary sciences. JACS is committed to disseminating cutting-edge research papers, covering a wide range of topics, and encompasses approximately 19,000 pages of Articles, Communications, and Perspectives annually. With a weekly publication frequency, JACS plays a vital role in advancing the field of chemistry by providing essential research.