ngx-mol-viewer:生物信息学中交互式分子可视化的角组件。

IF 3.9 Q2 MATHEMATICAL & COMPUTATIONAL BIOLOGY
Frontiers in bioinformatics Pub Date : 2025-06-26 eCollection Date: 2025-01-01 DOI:10.3389/fbinf.2025.1586744
Damiano Clementel, Alessio Del Conte, Alexander Miguel Monzon, Silvio C E Tosatto
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引用次数: 0

摘要

生物信息学的进步是由机器学习等技术推动的,并导致从经验观察和计算模型中产生的数据大幅增加。因此,通过整合来自不同来源的数据,知名的生物数据库在规模和中心地位上不断增长。虽然这些数据库的主要目标是通过应用程序编程接口(api)收集和分发数据,但直接在浏览器界面上提供可视化和分析工具对于用户理解数据至关重要,这增加了数据库的有用性和总体影响。目前,有一些前端框架可用于这些资源的用户界面(UI)和用户体验(UX)的持续开发。Angular是BioCompUP实验室中被广泛采用的最流行的框架之一。这项工作描述了一个可重用和可定制的组件库,这些组件可以很容易地集成到Angular框架中,以提供蛋白质分子的各个方面的可视化,比如它们的序列、结构和注释。目前,该库包括三个主要的独立组件。第一个是ngx结构查看器,它允许通过MolStar三维查看器对分子进行可视化。第二个是ngx序列查看器,它为单个序列或多个序列比对提供可视化和注释功能。第三个是ngx-feature -viewer,可以在同一分子上绘制和可视化各种生物注释。所有这些工具都可以通过Node Package Manager (NPM)下载,更多信息请访问https://biocomputingup.github.io/ngx-mol-viewers/(正在开发中)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

ngx-mol-viewers: Angular components for interactive molecular visualization in bioinformatics.

ngx-mol-viewers: Angular components for interactive molecular visualization in bioinformatics.

ngx-mol-viewers: Angular components for interactive molecular visualization in bioinformatics.

ngx-mol-viewers: Angular components for interactive molecular visualization in bioinformatics.

Advancements in bioinformatics have been propelled by technologies like machine learning and have resulted in substantial increases in data generated from both empirical observations and computational models. Hence, well-known biological databases are growing in size and centrality by integrating data from different sources. While the primary goal of these databases is to collect and distribute data through application programming interfaces (APIs), providing visualization and analysis tools directly on the browser interface is crucial for users to understand the data, which increases the usefulness and overall impact of the databases. Currently, some front-end frameworks are available for the sustained development of the user interface (UI) and user experience (UX) of these resources. Angular is one of the most popular frameworks to be broadly adopted within the BioCompUP laboratory. This work describes a library of reusable and customizable components that can be easily integrated into the Angular framework to provide visualizations of various aspects of protein molecules, such as their sequences, structures, and annotations. Currently, the library includes three main independent components. The first is the ngx-structure-viewer, which allows visualization of molecules through the MolStar three-dimensional viewer. The second is the ngx-sequence-viewer, which provides visualization and annotation capabilities for a single sequence or multiple sequence alignments. The third the ngx-features-viewer, enables the mapping and visualization of various biological annotations onto the same molecule. All these tools are available for download through the Node Package Manager (NPM), and more information is available at https://biocomputingup.github.io/ngx-mol-viewers/ (under development).

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