术中超声心动图分析肿瘤外科大出血:凝血曲线异常1例。

IF 1.3 Q3 ANESTHESIOLOGY
Saudi Journal of Anaesthesia Pub Date : 2025-07-01 Epub Date: 2025-06-16 DOI:10.4103/sja.sja_773_24
Thrivikrama P Tantry, Milan Hande, Pooja K Rao, Sunil P Shenoy
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引用次数: 0

摘要

在肿瘤手术患者中,术中使用粘弹性试验方法监测凝血的报道很少。文献中没有关于上述人群使用Sonoclot并随后纠正凝血异常的循证临床报告。我们在此报告10例大出血患者的凝血功能改变。术中凝血异常检测采用活化凝血时间、凝血率和血小板功能。在我们的系列研究中,最常见的超声心动图特征异常是形状不佳、暗淡、圆形的“峰”,表明纤维蛋白形成不规则。在少数受试者中也记录了稀释性凝血功能障碍和超纤溶事件。根据Sonoclot曲线评估,考虑适当输注血液制品。所有受试者均恢复良好。我们的结论是,Sonoclot分析显示了优化肿瘤外科大出血患者血液制品使用的潜力,需要进一步研究以建立标准化的方案并量化其影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Intraoperative Sonoclot analysis in oncosurgical massive hemorrhage: A case series of coagulation curve abnormalities.

Reports on intraoperative coagulation monitoring using viscoelastic testing methods are scarce in oncosurgical patients. Evidence-based clinical reports with the use of Sonoclot and subsequent corrections of coagulation abnormalities in above population are not available in the literature. We report here records of altered coagulation in 10 subjects with massive hemorrhage. Detection of intraoperative coagulation abnormalities was done using activated clotting time, clot rate, and platelet function. The most common Sonoclot signature abnormality found in our series was a poorly formed, dull, and rounded "peak," indicative of irregularities of fibrin formation. Dilutional coagulopathy and hyper-fibrinolysis events too were recorded in few subjects. Appropriate transfusions with blood products were considered based on Sonoclot curve assessment. All subjects had adequate recovery. We conclude that the Sonoclot analysis demonstrates potential for optimizing blood product use in oncosurgical patients with massive hemorrhage, warranting further research to establish standardized protocols and quantify its impact.

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来源期刊
CiteScore
1.90
自引率
8.30%
发文量
141
审稿时长
36 weeks
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