一项前瞻性随机对照试验的结果:肩关节置换术后疼痛自我管理和阿片类药物消费的术前教育对阿片类药物的使用和处置没有显著影响

Q2 Medicine
Maria F. Bozoghlian MD , Brady Wilkinson MD , Katherine Hadlandsmyth PhD , Natalie Glass PhD , James V. Nepola MD , Brendan M. Patterson MD, MPH
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引用次数: 0

摘要

背景:包括肩关节置换术在内的骨科手术后阿片类药物的处方率仍然很高。此外,只有一小部分患者能安全地处置剩余的阿片类药物。本研究的目的是测试术前教育干预对肩关节置换术后疼痛自我管理、阿片类药物消耗和阿片类药物处理的效果。方法采用单盲前瞻性随机试验,将受试者随机分为教育组和对照组,对随机状态不知情。对照组遵循术前标准护理操作。教育组观看了一段教育视频,并收到了书面教育材料,重点是疼痛自我管理以及负责任的阿片类药物使用和处置做法。教育组的受试者还获得了一个预付和预先写好地址的信封,用于处理阿片类药物。主要结局是两组术后剩余10粒或更多未使用阿片类药物患者比例的差异。次要指标阿片类药物处理率也比较了两组之间的差异。采用卡方检验进行比较。结果共纳入127名受试者进行分析。各组在年龄、体重指数、性别、吸烟状况或手术类型(解剖与反向肩关节置换术)方面无显著差异(所有P >;. 05)。术前教育前后阿片类药物的中位用量无显著差异(15片vs 21片,P = 0.7)。教育组与对照组患者未使用药片≥10粒的比例差异无统计学意义(73% vs 78%, P = 0.569)。实验组和对照组的阿片类药物处理率没有差异(分别为37%和31%,P = 0.5)。然而,当按年龄分层时,70岁的参与者处理未使用阿片类药物的比率(49%)明显高于70岁的参与者(29%,P = 0.041)。术前教育和标准化处理方法对肩关节置换术后阿片类药物的使用和处理没有显著影响。鉴于术前教育对阿片类药物消耗缺乏显著影响,本研究强调需要考虑在术后环境中其他干预措施,这些干预措施可能更有利于减少阿片类药物的消耗和促进阿片类药物的处置。此外,这些结果可以帮助外科医生避免过量处方,并可以告知外科医生哪些患者更有可能在手术后处理未使用的阿片类药物。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Preoperative education on pain self-management and opioid consumption does not significantly impact opioid use and disposal following shoulder arthroplasty: results of a prospective randomized controlled trial

Background

Prescription rates for opioid medications following orthopedic surgical procedures including shoulder arthroplasty continue to be high. In addition, only a small percentage of patients dispose of remaining opioid pills safely. The purpose of this study was to test the efficacy of preoperative education intervention on pain self-management, opioid consumption, and opioid disposal following shoulder arthroplasty.

Methods

A single-blinded prospective randomized trial was performed with subjects randomized to an education arm or a control arm and blinded to randomization status. The control group followed preoperative standard of care practices. The education group watched an educational video and received written educational material, focusing on pain self-management as well as responsible opioid use and disposal practices. Subjects in the education group were also provided with a prepaid and preaddressed envelope for opioid disposal. The primary outcome was the difference between groups in the proportion of patients who had 10 or more unused opioid pills remaining following surgery. The secondary outcome, opioid disposal rate, was also compared between groups. Comparisons were made using chi-square tests.

Results

A total of 127 participants were included for analysis. There were no significant differences between groups in age, body mass index, sex, smoking status, or type of procedure (anatomic vs. reverse shoulder arthroplasty) (all P > .05). There was no significant difference in median opioid consumption with or without preoperative education (15 pills vs. 21 pills, respectively, P = .7). There was no significant difference between education and control groups in proportion of patients with ≥10 unused pills (73% vs. 78%, P = .569). There was no difference in the rate of opioid disposal between education and control groups (37% vs. 31%, respectively, P = .5). However, when stratified by age, participants <70 years had significantly higher rates of disposal of unused opioids (49%) compared with those >70 years (29%, P = .041).

Discussion

Preoperative education and standardized disposal methods did not significantly impact opioid consumption and disposal following shoulder arthroplasty. Given the lack of significant impact of preoperative education on opioid consumption, this study highlights the need to consider other interventions in the postoperative setting that could be more beneficial in aiding with decreased opioid consumption and in promoting opioid disposal. Furthermore, these results can help surgeons avoid overprescribing and can inform surgeons on which patients are more likely to dispose of unused opioids following surgery.
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来源期刊
JSES International
JSES International Medicine-Surgery
CiteScore
2.80
自引率
0.00%
发文量
174
审稿时长
14 weeks
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