Piotr Czapski, Wiktoria Niegowska, Jan Domański, Aleksandra Witkowska, Jakub Wirkijowski, Paulina Woźniak, Katarzyna Januszewska, Małgorzta Kupisz-Urbańska, Ada Sawicka, Piotr Jankowski
{"title":"他汀类药物对老年心力衰竭患者肌肉力量的影响。","authors":"Piotr Czapski, Wiktoria Niegowska, Jan Domański, Aleksandra Witkowska, Jakub Wirkijowski, Paulina Woźniak, Katarzyna Januszewska, Małgorzta Kupisz-Urbańska, Ada Sawicka, Piotr Jankowski","doi":"10.36740/Merkur202503101","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>Aim: To evaluate the association between statin use and muscle strength in older adults with heart failure (HF).</p><p><strong>Patients and methods: </strong>Materials and Methods: Hospitalized, older adults with HF were divided into two subgroups: use statin (US) and not use statin (N-US). Muscle strength was measured using a hand-held dynamometer and HF was assessed based on the New York Heart Association NYHA functional classification.</p><p><strong>Results: </strong>Results: 194 patients (median age 82 [78-86] years), 90 patients in US and 104 in N-US group. Muscle strength didn't differ significantly in US vs N-US group, 19.74kg (15.48-27.18) vs 17.58kg (12.73-25.66), p=0.098. In a multivariate analysis age, sex, NYHA class, hemoglobin concentration, presence of atrial fibrillation, and hypothyroidism were found to be independent factors of muscle strength (p<0.001, p<0.001, p<0.01, p<0.001, p=0.02, p=0.04 respectively).</p><p><strong>Conclusion: </strong>Conclusions: statin use is not related to decreased muscle strength in older adults with HF.</p>","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"53 3","pages":"295-301"},"PeriodicalIF":0.0000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Statin use and muscle strength in older patients with heart failure.\",\"authors\":\"Piotr Czapski, Wiktoria Niegowska, Jan Domański, Aleksandra Witkowska, Jakub Wirkijowski, Paulina Woźniak, Katarzyna Januszewska, Małgorzta Kupisz-Urbańska, Ada Sawicka, Piotr Jankowski\",\"doi\":\"10.36740/Merkur202503101\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>Aim: To evaluate the association between statin use and muscle strength in older adults with heart failure (HF).</p><p><strong>Patients and methods: </strong>Materials and Methods: Hospitalized, older adults with HF were divided into two subgroups: use statin (US) and not use statin (N-US). Muscle strength was measured using a hand-held dynamometer and HF was assessed based on the New York Heart Association NYHA functional classification.</p><p><strong>Results: </strong>Results: 194 patients (median age 82 [78-86] years), 90 patients in US and 104 in N-US group. Muscle strength didn't differ significantly in US vs N-US group, 19.74kg (15.48-27.18) vs 17.58kg (12.73-25.66), p=0.098. In a multivariate analysis age, sex, NYHA class, hemoglobin concentration, presence of atrial fibrillation, and hypothyroidism were found to be independent factors of muscle strength (p<0.001, p<0.001, p<0.01, p<0.001, p=0.02, p=0.04 respectively).</p><p><strong>Conclusion: </strong>Conclusions: statin use is not related to decreased muscle strength in older adults with HF.</p>\",\"PeriodicalId\":39518,\"journal\":{\"name\":\"Polski Merkuriusz Lekarski\",\"volume\":\"53 3\",\"pages\":\"295-301\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Polski Merkuriusz Lekarski\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.36740/Merkur202503101\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Polski Merkuriusz Lekarski","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.36740/Merkur202503101","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
Statin use and muscle strength in older patients with heart failure.
Objective: Aim: To evaluate the association between statin use and muscle strength in older adults with heart failure (HF).
Patients and methods: Materials and Methods: Hospitalized, older adults with HF were divided into two subgroups: use statin (US) and not use statin (N-US). Muscle strength was measured using a hand-held dynamometer and HF was assessed based on the New York Heart Association NYHA functional classification.
Results: Results: 194 patients (median age 82 [78-86] years), 90 patients in US and 104 in N-US group. Muscle strength didn't differ significantly in US vs N-US group, 19.74kg (15.48-27.18) vs 17.58kg (12.73-25.66), p=0.098. In a multivariate analysis age, sex, NYHA class, hemoglobin concentration, presence of atrial fibrillation, and hypothyroidism were found to be independent factors of muscle strength (p<0.001, p<0.001, p<0.01, p<0.001, p=0.02, p=0.04 respectively).
Conclusion: Conclusions: statin use is not related to decreased muscle strength in older adults with HF.
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