脊髓刺激治疗慢性疼痛:一项来自加拿大三级中心患者的回顾性队列研究。

IF 3.3 3区 医学 Q1 ANESTHESIOLOGY
Hillary A Chan, Bhavya Kapoor, Yeshith Rai, Falilat Karatu, Farhang Jalilian, John Hanlon, Anuj Bhatia, David Sussman, Calvin Diep, Karim S Ladha, Akash Goel
{"title":"脊髓刺激治疗慢性疼痛:一项来自加拿大三级中心患者的回顾性队列研究。","authors":"Hillary A Chan, Bhavya Kapoor, Yeshith Rai, Falilat Karatu, Farhang Jalilian, John Hanlon, Anuj Bhatia, David Sussman, Calvin Diep, Karim S Ladha, Akash Goel","doi":"10.1007/s12630-025-03001-6","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>Spinal cord stimulation (SCS) is a surgical intervention for patients with neuropathic pain refractory to medical management. There are limited data on its outcomes from Canadian centres. We aimed to describe the indications, patient- and procedure-related characteristics, and outcomes of patients who underwent SCS implantation at a Canadian tertiary centre.</p><p><strong>Methods: </strong>We conducted a retrospective cohort study of patients who underwent SCS at St. Michael's Hospital (Toronto, ON, Canada) between 1 January 2020 and 31 July 2023. We collected data on patient demographics, analgesic use, type of SCS trial (percutaneous vs tunneled), indication, antibiotic use during and after surgery, and complications.</p><p><strong>Results: </strong>We included 100 patients with a mean (standard deviation) age of 62 (14) yr. Indications included chronic pain after spinal surgery (n = 44), chronic back pain (no prior spine surgery) (n = 22), complex regional pain syndrome (n = 6), spinal stenosis (n = 4), and visceral pain (n = 4). Complications included implantable pulse generator-associated pain (47%), lead migration (14%), lead fracture (9%), surgical site infection (2%), and cerebrospinal fluid leak (6%). Almost all patients were on pharmacotherapy for pain relief at baseline (n = 96) and agents included opioids, nonsteroidal anti-inflammatory drugs, anticonvulsants, and antidepressants.</p><p><strong>Conclusions: </strong>In this cohort of patients who underwent SCS implantation at a Canadian tertiary centre, infection and lead migration rates were consistent with global estimates (3.8% and up to 27%, respectively); nevertheless, we observed high rates of dural puncture compared with an expected incidence of 0.48%.</p>","PeriodicalId":56145,"journal":{"name":"Canadian Journal of Anesthesia-Journal Canadien D Anesthesie","volume":" ","pages":"1110-1117"},"PeriodicalIF":3.3000,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Spinal cord stimulation for chronic pain: a retrospective cohort study of patients from a Canadian tertiary centre.\",\"authors\":\"Hillary A Chan, Bhavya Kapoor, Yeshith Rai, Falilat Karatu, Farhang Jalilian, John Hanlon, Anuj Bhatia, David Sussman, Calvin Diep, Karim S Ladha, Akash Goel\",\"doi\":\"10.1007/s12630-025-03001-6\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>Spinal cord stimulation (SCS) is a surgical intervention for patients with neuropathic pain refractory to medical management. There are limited data on its outcomes from Canadian centres. We aimed to describe the indications, patient- and procedure-related characteristics, and outcomes of patients who underwent SCS implantation at a Canadian tertiary centre.</p><p><strong>Methods: </strong>We conducted a retrospective cohort study of patients who underwent SCS at St. Michael's Hospital (Toronto, ON, Canada) between 1 January 2020 and 31 July 2023. We collected data on patient demographics, analgesic use, type of SCS trial (percutaneous vs tunneled), indication, antibiotic use during and after surgery, and complications.</p><p><strong>Results: </strong>We included 100 patients with a mean (standard deviation) age of 62 (14) yr. Indications included chronic pain after spinal surgery (n = 44), chronic back pain (no prior spine surgery) (n = 22), complex regional pain syndrome (n = 6), spinal stenosis (n = 4), and visceral pain (n = 4). Complications included implantable pulse generator-associated pain (47%), lead migration (14%), lead fracture (9%), surgical site infection (2%), and cerebrospinal fluid leak (6%). Almost all patients were on pharmacotherapy for pain relief at baseline (n = 96) and agents included opioids, nonsteroidal anti-inflammatory drugs, anticonvulsants, and antidepressants.</p><p><strong>Conclusions: </strong>In this cohort of patients who underwent SCS implantation at a Canadian tertiary centre, infection and lead migration rates were consistent with global estimates (3.8% and up to 27%, respectively); nevertheless, we observed high rates of dural puncture compared with an expected incidence of 0.48%.</p>\",\"PeriodicalId\":56145,\"journal\":{\"name\":\"Canadian Journal of Anesthesia-Journal Canadien D Anesthesie\",\"volume\":\" \",\"pages\":\"1110-1117\"},\"PeriodicalIF\":3.3000,\"publicationDate\":\"2025-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Canadian Journal of Anesthesia-Journal Canadien D Anesthesie\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s12630-025-03001-6\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/7/8 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q1\",\"JCRName\":\"ANESTHESIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Canadian Journal of Anesthesia-Journal Canadien D Anesthesie","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s12630-025-03001-6","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/7/8 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"ANESTHESIOLOGY","Score":null,"Total":0}
引用次数: 0

摘要

目的:脊髓刺激(SCS)是一种外科治疗难治性神经性疼痛的方法。来自加拿大各中心的有关其结果的数据有限。我们的目的是描述在加拿大三级中心接受SCS植入的患者的适应症、患者和手术相关的特征和结果。方法:我们对2020年1月1日至2023年7月31日期间在St. Michael's医院(Toronto, ON, Canada)接受SCS治疗的患者进行了回顾性队列研究。我们收集了患者人口统计学、止痛药使用、SCS试验类型(经皮vs隧道)、适应症、手术中和术后抗生素使用以及并发症的数据。结果:我们纳入了100例患者,平均(标准差)年龄为62(14)岁。适应症包括脊柱手术后慢性疼痛(n = 44),慢性背痛(n = 22),复杂区域疼痛综合征(n = 6),椎管狭窄(n = 4)和内脏疼痛(n = 4)。并发症包括植入式脉冲发生器相关疼痛(47%)、铅迁移(14%)、铅骨折(9%)、手术部位感染(2%)和脑脊液漏(6%)。几乎所有患者在基线时都在接受药物治疗以缓解疼痛(n = 96),药物包括阿片类药物、非甾体抗炎药、抗惊厥药和抗抑郁药。结论:在加拿大三级中心接受SCS植入的患者队列中,感染和铅迁移率与全球估计一致(分别为3.8%和27%);然而,与0.48%的预期发生率相比,我们观察到硬脑膜穿刺率很高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Spinal cord stimulation for chronic pain: a retrospective cohort study of patients from a Canadian tertiary centre.

Purpose: Spinal cord stimulation (SCS) is a surgical intervention for patients with neuropathic pain refractory to medical management. There are limited data on its outcomes from Canadian centres. We aimed to describe the indications, patient- and procedure-related characteristics, and outcomes of patients who underwent SCS implantation at a Canadian tertiary centre.

Methods: We conducted a retrospective cohort study of patients who underwent SCS at St. Michael's Hospital (Toronto, ON, Canada) between 1 January 2020 and 31 July 2023. We collected data on patient demographics, analgesic use, type of SCS trial (percutaneous vs tunneled), indication, antibiotic use during and after surgery, and complications.

Results: We included 100 patients with a mean (standard deviation) age of 62 (14) yr. Indications included chronic pain after spinal surgery (n = 44), chronic back pain (no prior spine surgery) (n = 22), complex regional pain syndrome (n = 6), spinal stenosis (n = 4), and visceral pain (n = 4). Complications included implantable pulse generator-associated pain (47%), lead migration (14%), lead fracture (9%), surgical site infection (2%), and cerebrospinal fluid leak (6%). Almost all patients were on pharmacotherapy for pain relief at baseline (n = 96) and agents included opioids, nonsteroidal anti-inflammatory drugs, anticonvulsants, and antidepressants.

Conclusions: In this cohort of patients who underwent SCS implantation at a Canadian tertiary centre, infection and lead migration rates were consistent with global estimates (3.8% and up to 27%, respectively); nevertheless, we observed high rates of dural puncture compared with an expected incidence of 0.48%.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
8.50
自引率
7.10%
发文量
161
审稿时长
6-12 weeks
期刊介绍: The Canadian Journal of Anesthesia (the Journal) is owned by the Canadian Anesthesiologists’ Society and is published by Springer Science + Business Media, LLM (New York). From the first year of publication in 1954, the international exposure of the Journal has broadened considerably, with articles now received from over 50 countries. The Journal is published monthly, and has an impact Factor (mean journal citation frequency) of 2.127 (in 2012). Article types consist of invited editorials, reports of original investigations (clinical and basic sciences articles), case reports/case series, review articles, systematic reviews, accredited continuing professional development (CPD) modules, and Letters to the Editor. The editorial content, according to the mission statement, spans the fields of anesthesia, acute and chronic pain, perioperative medicine and critical care. In addition, the Journal publishes practice guidelines and standards articles relevant to clinicians. Articles are published either in English or in French, according to the language of submission.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信