肾移植后男性乳腺癌：病例报告及文献回顾。

IF 0.7 4区医学 Q4 TRANSPLANTATION

Experimental and Clinical Transplantation Pub Date : 2025-06-01 DOI:10.6002/ect.2025.0083

Hanen Chaker, Soumaya Yaich, Hanen Abid, Souhir Khemiri, Slim Charfi, Mondher Masmoudi, Mohamed Ben Hmida, Tahya Boudawara, Afef Khanfir, Khawla Kammoun

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引用次数: 0

摘要

肾移植后长期免疫抑制可导致恶性肿瘤。在这个病例研究中，我们报告了一个罕见的病例，乳腺癌发生在33年的肾脏移植后的男性。这个55岁的肾脏移植病人表现为右乳房肿块。活检显示浸润性癌。免疫组化检查雌激素阳性。患者行右侧乳房切除术并腋窝清扫术。开始以多西紫杉醇为基础的化疗和放疗。辅助治疗为他莫昔芬，并由硫唑嘌呤转为西罗莫司。随访显示患者于就诊后24个月死亡。通过这个病例，我们强调警惕这种罕见癌症的重要性，这种癌症通常在晚期才被诊断出来，可能会对预后产生负面影响。筛查危险因素至关重要。

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Male Breast Cancer After Kidney Transplant: Case Report and Literature Revue.

Long-term immunosuppression can lead to malignant tumors after kidney transplant. In this case study, we report a rare case of breast cancer occurring in a man after 33 years of kidney transplant. This 55-year-old kidney transplant patient presented with a right breast mass. The biopsy showed an infiltrating carcinoma. The immunohistochemical study was positive for estrogen. The patient underwent a right mastectomy with axillary dissection. Chemotherapy based on docetaxel and radiotherapy was started. Adjuvant treatment with tamoxifen and a switch from azathioprine to sirolimus were conducted. Follow-up showed that the patient died 24 months after presentation. Through this case, we emphasize the importance of vigilance about this rare cancer, often diagnosed at a late stage, which can negatively affect prognosis. Screening for risk factors is crucial.

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来源期刊

Experimental and Clinical Transplantation 医学-移植

CiteScore

1.40

自引率

11.10%

发文量

258

审稿时长

6-12 weeks

期刊介绍： The scope of the journal includes the following: Surgical techniques, innovations, and novelties; Immunobiology and immunosuppression; Clinical results; Complications; Infection; Malignancies; Organ donation; Organ and tissue procurement and preservation; Sociological and ethical issues; Xenotransplantation.