Daniel A Kago-Tague, Fabricia N Guimeya, Joseph Kamtchum-Tatuene, Dominique Enyama, Euranie J Kouam, Hubert D Mbassi, Seraphin Nguefack
{"title":"喀麦隆儿童中风的病因和临床表现。","authors":"Daniel A Kago-Tague, Fabricia N Guimeya, Joseph Kamtchum-Tatuene, Dominique Enyama, Euranie J Kouam, Hubert D Mbassi, Seraphin Nguefack","doi":"10.4314/gmj.v59i1.2","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>The aim was to determine the aetiological factors and clinical and paraclinical aspects of stroke in children in Cameroon.</p><p><strong>Design: </strong>retrospective study of the records.</p><p><strong>Setting: </strong>At two university hospitals in the city of Yaoundé (Yaoundé Gynaeco-Obstetric and Paediatric Hospital and the Chantal Biya Foundation Mother and Child Centre).</p><p><strong>Participants: </strong>47 children with stroke for seven and half years.</p><p><strong>Interventions: </strong>Data were collected from medical records. The variables studied included clinical and paraclinical data.</p><p><strong>Main outcome measures: </strong>Key variables were summarised in the form of mean ± standard deviation, frequencies and percentages.</p><p><strong>Results: </strong>The mean age was 6.5±2.8 years. The Male Female sex ratio was 1.8:1. The average consultation time was 31.8 hours. Hemiplegia/hemiparesis (95.7%) was the main clinical manifestation, associated with signs such as convulsions (27.7%), fever (46.8%) and pallor (27.7%). Ischaemic and haemorrhagic stroke accounted for 41 cases (87.2%) and 6 cases (12.8%), respectively. The aetiological factors for ischaemic stroke were sickle cell disease (72.3%), sepsis (4.2%), protein S deficiency (2.1%) and dilated cardiomyopathy with mitral insufficiency (2.1%). The aetiology was not found in 3 patients (6.4%) with ischaemic stroke. Apart from sickle cell disease (66.6%), the aetiological factors for haemorrhagic stroke were idiopathic thrombocytopenic purpura (16.7%) and haemophilia B (16.7%). Ischaemia mainly involved the middle cerebral artery (86.1%). Haemorrhagic attacks were mainly supratentorial.</p><p><strong>Conclusion: </strong>In urban Cameroon, strokes frequently occur around the age of 6, with a predominance of ischaemic strokes resulting in motor deficits. Sickle cell disease is the most common cause.</p><p><strong>Funding: </strong>None declared.</p>","PeriodicalId":94319,"journal":{"name":"Ghana medical journal","volume":"59 1","pages":"10-14"},"PeriodicalIF":0.0000,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12224125/pdf/","citationCount":"0","resultStr":"{\"title\":\"Causes and clinical presentation of stroke in children in Cameroon.\",\"authors\":\"Daniel A Kago-Tague, Fabricia N Guimeya, Joseph Kamtchum-Tatuene, Dominique Enyama, Euranie J Kouam, Hubert D Mbassi, Seraphin Nguefack\",\"doi\":\"10.4314/gmj.v59i1.2\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>The aim was to determine the aetiological factors and clinical and paraclinical aspects of stroke in children in Cameroon.</p><p><strong>Design: </strong>retrospective study of the records.</p><p><strong>Setting: </strong>At two university hospitals in the city of Yaoundé (Yaoundé Gynaeco-Obstetric and Paediatric Hospital and the Chantal Biya Foundation Mother and Child Centre).</p><p><strong>Participants: </strong>47 children with stroke for seven and half years.</p><p><strong>Interventions: </strong>Data were collected from medical records. The variables studied included clinical and paraclinical data.</p><p><strong>Main outcome measures: </strong>Key variables were summarised in the form of mean ± standard deviation, frequencies and percentages.</p><p><strong>Results: </strong>The mean age was 6.5±2.8 years. The Male Female sex ratio was 1.8:1. The average consultation time was 31.8 hours. Hemiplegia/hemiparesis (95.7%) was the main clinical manifestation, associated with signs such as convulsions (27.7%), fever (46.8%) and pallor (27.7%). Ischaemic and haemorrhagic stroke accounted for 41 cases (87.2%) and 6 cases (12.8%), respectively. The aetiological factors for ischaemic stroke were sickle cell disease (72.3%), sepsis (4.2%), protein S deficiency (2.1%) and dilated cardiomyopathy with mitral insufficiency (2.1%). The aetiology was not found in 3 patients (6.4%) with ischaemic stroke. Apart from sickle cell disease (66.6%), the aetiological factors for haemorrhagic stroke were idiopathic thrombocytopenic purpura (16.7%) and haemophilia B (16.7%). Ischaemia mainly involved the middle cerebral artery (86.1%). Haemorrhagic attacks were mainly supratentorial.</p><p><strong>Conclusion: </strong>In urban Cameroon, strokes frequently occur around the age of 6, with a predominance of ischaemic strokes resulting in motor deficits. Sickle cell disease is the most common cause.</p><p><strong>Funding: </strong>None declared.</p>\",\"PeriodicalId\":94319,\"journal\":{\"name\":\"Ghana medical journal\",\"volume\":\"59 1\",\"pages\":\"10-14\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12224125/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Ghana medical journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4314/gmj.v59i1.2\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Ghana medical journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4314/gmj.v59i1.2","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Causes and clinical presentation of stroke in children in Cameroon.
Objective: The aim was to determine the aetiological factors and clinical and paraclinical aspects of stroke in children in Cameroon.
Design: retrospective study of the records.
Setting: At two university hospitals in the city of Yaoundé (Yaoundé Gynaeco-Obstetric and Paediatric Hospital and the Chantal Biya Foundation Mother and Child Centre).
Participants: 47 children with stroke for seven and half years.
Interventions: Data were collected from medical records. The variables studied included clinical and paraclinical data.
Main outcome measures: Key variables were summarised in the form of mean ± standard deviation, frequencies and percentages.
Results: The mean age was 6.5±2.8 years. The Male Female sex ratio was 1.8:1. The average consultation time was 31.8 hours. Hemiplegia/hemiparesis (95.7%) was the main clinical manifestation, associated with signs such as convulsions (27.7%), fever (46.8%) and pallor (27.7%). Ischaemic and haemorrhagic stroke accounted for 41 cases (87.2%) and 6 cases (12.8%), respectively. The aetiological factors for ischaemic stroke were sickle cell disease (72.3%), sepsis (4.2%), protein S deficiency (2.1%) and dilated cardiomyopathy with mitral insufficiency (2.1%). The aetiology was not found in 3 patients (6.4%) with ischaemic stroke. Apart from sickle cell disease (66.6%), the aetiological factors for haemorrhagic stroke were idiopathic thrombocytopenic purpura (16.7%) and haemophilia B (16.7%). Ischaemia mainly involved the middle cerebral artery (86.1%). Haemorrhagic attacks were mainly supratentorial.
Conclusion: In urban Cameroon, strokes frequently occur around the age of 6, with a predominance of ischaemic strokes resulting in motor deficits. Sickle cell disease is the most common cause.