{"title":"[不同放射性核素的SPECT定量灵敏度校准随时间变化的验证]。","authors":"Tomohiro Sato","doi":"10.6009/jjrt.25-1552","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>In single-photon emission computed tomography (SPECT), the standardized uptake value requires a becquerel calibration factor (BCF). The changes over time in BCF due to different radionuclides and collimators was examined.</p><p><strong>Methods: </strong>The BCF (cps/MBq) was monthly calculated from the radioactivity of syringe formulations and dispensed sources measured with a dose calibrator, and planar acquisition counts. In addition, relative errors with respect to the maximum BCF over 44 months were calculated.</p><p><strong>Results: </strong>The average BCF was 46.0 for <sup>123</sup>I with a low-penetration high-resolution collimator (<sup>123</sup>I-LPHR) and 124.1 for <sup>131</sup>I with a medium-energy low-penetration collimator (<sup>131</sup>I-MELP). The standard deviation of the BCF for any radionuclides and collimators was less than 3.4 and the differences between detectors were small. Relative errors of the BCF were less than 10% for <sup>99m</sup>Tc with a low-energy high-resolution collimator (<sup>99m</sup>Tc-LEHR), <sup>123</sup>I-MELP, <sup>67</sup>Ga-MELP, and <sup>131</sup>I-MELP, and less than 5% for <sup>123</sup>I-MELP. Relative errors for <sup>123</sup>I-LEHR and <sup>123</sup>I-LPHR were initially slightly higher but decreased to less than 10% after 7 months.</p><p><strong>Conclusion: </strong>The BCF measured by planar acquisition were stable and reproducible over time with a wide variety of nuclides and collimators.</p>","PeriodicalId":74309,"journal":{"name":"Nihon Hoshasen Gijutsu Gakkai zasshi","volume":"81 9","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Validation of Changes over Time in Sensitivity Calibrations of SPECT Quantification for Different Radionuclides].\",\"authors\":\"Tomohiro Sato\",\"doi\":\"10.6009/jjrt.25-1552\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>In single-photon emission computed tomography (SPECT), the standardized uptake value requires a becquerel calibration factor (BCF). The changes over time in BCF due to different radionuclides and collimators was examined.</p><p><strong>Methods: </strong>The BCF (cps/MBq) was monthly calculated from the radioactivity of syringe formulations and dispensed sources measured with a dose calibrator, and planar acquisition counts. In addition, relative errors with respect to the maximum BCF over 44 months were calculated.</p><p><strong>Results: </strong>The average BCF was 46.0 for <sup>123</sup>I with a low-penetration high-resolution collimator (<sup>123</sup>I-LPHR) and 124.1 for <sup>131</sup>I with a medium-energy low-penetration collimator (<sup>131</sup>I-MELP). The standard deviation of the BCF for any radionuclides and collimators was less than 3.4 and the differences between detectors were small. Relative errors of the BCF were less than 10% for <sup>99m</sup>Tc with a low-energy high-resolution collimator (<sup>99m</sup>Tc-LEHR), <sup>123</sup>I-MELP, <sup>67</sup>Ga-MELP, and <sup>131</sup>I-MELP, and less than 5% for <sup>123</sup>I-MELP. Relative errors for <sup>123</sup>I-LEHR and <sup>123</sup>I-LPHR were initially slightly higher but decreased to less than 10% after 7 months.</p><p><strong>Conclusion: </strong>The BCF measured by planar acquisition were stable and reproducible over time with a wide variety of nuclides and collimators.</p>\",\"PeriodicalId\":74309,\"journal\":{\"name\":\"Nihon Hoshasen Gijutsu Gakkai zasshi\",\"volume\":\"81 9\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nihon Hoshasen Gijutsu Gakkai zasshi\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.6009/jjrt.25-1552\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nihon Hoshasen Gijutsu Gakkai zasshi","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.6009/jjrt.25-1552","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[Validation of Changes over Time in Sensitivity Calibrations of SPECT Quantification for Different Radionuclides].
Purpose: In single-photon emission computed tomography (SPECT), the standardized uptake value requires a becquerel calibration factor (BCF). The changes over time in BCF due to different radionuclides and collimators was examined.
Methods: The BCF (cps/MBq) was monthly calculated from the radioactivity of syringe formulations and dispensed sources measured with a dose calibrator, and planar acquisition counts. In addition, relative errors with respect to the maximum BCF over 44 months were calculated.
Results: The average BCF was 46.0 for 123I with a low-penetration high-resolution collimator (123I-LPHR) and 124.1 for 131I with a medium-energy low-penetration collimator (131I-MELP). The standard deviation of the BCF for any radionuclides and collimators was less than 3.4 and the differences between detectors were small. Relative errors of the BCF were less than 10% for 99mTc with a low-energy high-resolution collimator (99mTc-LEHR), 123I-MELP, 67Ga-MELP, and 131I-MELP, and less than 5% for 123I-MELP. Relative errors for 123I-LEHR and 123I-LPHR were initially slightly higher but decreased to less than 10% after 7 months.
Conclusion: The BCF measured by planar acquisition were stable and reproducible over time with a wide variety of nuclides and collimators.
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