The Relationships Between Patients' Demographic Characteristics, Comorbid Diseases, American Society of Anesthesiologists Scores and Inflammation Indexes: A Retrospective Study.

Objective: Parameters that can provide information about patients' current status are very important in preoperative evaluation. The systemic immune inflammation index (SII), and systemic inflammation response index (SIRI) can be easily calculated with a simple hemogram test, and this testing is frequently requested in preoperative preparation. The aim of this research was to examine the relationship between the SII, and SIRI, along with the demographic characteristics and postoperative clinical course of the patient.

Methods: In the study, the records of patients who presented to the anesthesia outpatient clinic for preoperative preparation were retrospectively reviewed. In this study, the relationships between the SII, and SIRI and each patients' demographic characteristics, and the American Society of Anesthesiologists (ASA) score, comorbid disease, and length of hospital stay were examined.

Results: For the SII value, there was a statistically significant difference between the ASA1 and ASA2 groups and between the ASA2 and ASA3 groups there was no significant difference between the ASA3 and ASA4 groups (P < 0.001, P < 0.001, P=0.17, respectively). There were statistically significant differences between the ASA1 and ASA2, ASA2 and ASA3, and ASA3 and ASA4 groups for the SIRI value (P < 0.001, P < 0.001, P < 0.001, respectively).

Conclusion: The findings showed relationships between the SII, SIRI, neutrophil-lymphocyte ratio, and platelet-lymphocyte ratio and an increase in patients' ASA scores. In multivariate analysis, some demographic characteristics of the patients, comorbidities, and the postoperative course were found to be independent risk factors predicting SII and SIRI.