行走早发性脊柱侧凸患者磁控生长棒后全椎弓根螺钉后路脊柱融合术:影像学和外科结果

IF 1.6 Q3 CLINICAL NEUROLOGY
Sergio De Salvatore, Paolo Brigato, Leonardo Oggiano, Davide Palombi, Gian Mario Sangiovanni, Edoardo Costici, Sergio Sessa, Pier Francesco Costici
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引用次数: 0

摘要

目的:早发性脊柱侧凸(EOS)显著影响肺发育和预期寿命。磁控生长棒(MCGR)有效地促进胸部生长,同时管理曲率进展。本研究旨在评估明确脊柱融合对接受mcgr治疗的EOS患者残留畸形和并发症的影响。方法:该研究包括27例在2017年1月至2022年9月期间接受最终融合手术的EOS患者。主要结果是评估术后冠状位和矢状位影像学参数,至少随访2年(FUP)。次要结局包括主要并发症(≥IIIB,根据Clavien-Dindo分级)、手术时间、出血量和住院时间(LOS)。结果:关节融合术对主弯(45.5°和33.5°,p = 0.003, Brunner-Munzel检验统计量= - 3.869254)和胸后凸(TK)(19.8°和13.5°,p = 0.002, Brunner-Munzel检验统计量= - 2.258845)有统计学影响,并在最后随访时维持。手术平均时间为254.2±39.5 min(范围:195 ~ 336 min),平均出血量为574.1±255.1 mL(范围:200 ~ 1300 mL)。平均生存时间(LOS)为8.5±1.8天(范围:6-13天)。最终融合后,5例患者(18.5%)出现并发症,其中1例为严重并发症。结论:这项研究表明,毕业手术后冠状和矢状面对齐有了实质性的改善,并在两年的FUP中保持了这一结果。需要更大样本量的进一步研究,以提供更全面的影像学和手术结果评估,并建立MCGR毕业手术中植入物密度的指南。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
All-pedicle screw posterior spinal fusion after magnetically controlled growing rods in walking early-onset scoliosis patients: radiographic and surgical outcomes.

Purpose: Early-onset scoliosis (EOS) significantly affects lung development and life expectancy. Magnetically Controlled Growing Rods (MCGR) effectively promote thoracic growth while managing curvature progression. This study aims to assess the impact of definitive spinal fusion on residual deformity and complications in EOS patients treated with MCGRs.

Methods: The study included 27 EOS patients who underwent final fusion surgery between January 2017 and September 2022. The primary outcome was the evaluation of coronal and sagittal radiographic parameters postoperatively and at a minimum of 2 years of follow-up (FUP). Secondary outcomes included major complications (≥ IIIB, according to Clavien-Dindo Classification), surgery duration, blood loss and length of hospital stay (LOS).

Results: Major curve (45.5° and 33.5°, p = 0.003, Brunner-Munzel Test Statistic = - 3.869254) and Thoracic Kyphosis (TK) (19.8° and 13.5°, p = 0.002, Brunner-Munzel Test Statistic = - 2.258845) were statistically impacted by arthrodesis, and maintained at the final follow-up. The surgeries had an average duration of 254.2 ± 39.5 min (range: 195-336 min) and an average blood loss of 574.1 ± 255.1 mL (range: 200-1300 mL). The mean LOS was 8.5 ± 1.8 days (range: 6-13 days). Following the final fusion, 5 patients (18.5%) developed a complication, of which one was classified as major.

Conclusions: This study demonstrated substantial improvements in coronal and sagittal alignment following graduation surgery, with results maintained at the two-year FUP. Further research with larger sample sizes is needed to provide a more comprehensive assessment of radiographic and surgical outcomes and to establish guidelines for implant density in MCGR graduation surgery.

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来源期刊
CiteScore
3.20
自引率
18.80%
发文量
167
期刊介绍: Spine Deformity the official journal of the?Scoliosis Research Society is a peer-refereed publication to disseminate knowledge on basic science and clinical research into the?etiology?biomechanics?treatment?methods and outcomes of all types of?spinal deformities. The international members of the Editorial Board provide a worldwide perspective for the journal's area of interest.The?journal?will enhance the mission of the Society which is to foster the optimal care of all patients with?spine?deformities worldwide. Articles published in?Spine Deformity?are Medline indexed in PubMed.? The journal publishes original articles in the form of clinical and basic research. Spine Deformity will only publish studies that have institutional review board (IRB) or similar ethics committee approval for human and animal studies and have strictly observed these guidelines. The minimum follow-up period for follow-up clinical studies is 24 months.
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