肠道微生物诱导的长链非编码RNA Snhg9调控人类恶性肿瘤的发展

IF 2.2 4区医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL

Current molecular medicine Pub Date : 2025-07-03 DOI:10.2174/0115665240366916250629064055

Dengke Jia, Yaping He, Qianle Chen, Yawu Zhang

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引用次数: 0

摘要

肠道微生物通过免疫系统的识别及其对多种代谢途径的影响来影响人类恶性肿瘤的进展。长链非编码RNA是参与人类恶性肿瘤进展的肠道微生物群的关键靶点。目前的研究表明，长链非编码RNA Snhg9与肠道微生物之间存在密切的串扰，并广泛参与人类恶性肿瘤的进展。深入研究长链非编码RNA与肠道菌群的相互作用以及snhg9的内在调控机制，将为今后人类恶性肿瘤的研究提供新的有力的治疗靶点。

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Gut Microbiota-Induced Long Non-Coding RNA Snhg9 Regulates the Development of Human Malignant Tumors.

Gut microbes influence the progression of human malignancies through their recognition by the immune system and their effects on numerous metabolic pathways. Long non-coding RNA is a key target of intestinal microbiota involved in the progression of human malignant tumors. Current research shows that there is a close cross-talk between long non-coding RNA Snhg9 and intestinal microorganisms, and it is widely involved in the progression of human malignant tumors. An in-depth study of the interaction between long non-coding RNA and intestinal flora and the intrinsic regulatory mechanism of snhg9 will provide new and powerful therapeutic targets for future research on human malignant tumors.

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来源期刊

Current molecular medicine 医学-医学：研究与实验

CiteScore

5.00

自引率

4.00%

发文量

141

审稿时长

4-8 weeks

期刊介绍： Current Molecular Medicine is an interdisciplinary journal focused on providing the readership with current and comprehensive reviews/ mini-reviews, original research articles, short communications/letters and drug clinical trial studies on fundamental molecular mechanisms of disease pathogenesis, the development of molecular-diagnosis and/or novel approaches to rational treatment. The reviews should be of significant interest to basic researchers and clinical investigators in molecular medicine. Periodically the journal invites guest editors to devote an issue on a basic research area that shows promise to advance our understanding of the molecular mechanism(s) of a disease or has potential for clinical applications.