{"title":"癌症患者与免疫治疗有关的神经系统并发症","authors":"Gabriela Montecinos MD, Florencia del Río MD","doi":"10.1016/j.rmclc.2025.06.001","DOIUrl":null,"url":null,"abstract":"<div><div>Immune checkpoint inhibitors, better known as immunotherapies, have revolutionized oncological treatment, allowing long-lasting and even curative tumor responses in various neoplasms. Their use, however, is associated with immunological adverse effects, among which neurological adverse effects represent a rare but clinically relevant entity.</div><div>This article addresses the epidemiology, classification, diagnostic keys and management of the most frequent neurological complications of immunotherapies, providing health professionals, and especially neurologists, with key tools for their recognition and timely treatment.</div></div>","PeriodicalId":31544,"journal":{"name":"Revista Medica Clinica Las Condes","volume":"36 3","pages":"Pages 146-155"},"PeriodicalIF":0.4000,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Complicaciones neurológicas relacionadas con la inmunoterapia en pacientes oncológicos\",\"authors\":\"Gabriela Montecinos MD, Florencia del Río MD\",\"doi\":\"10.1016/j.rmclc.2025.06.001\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Immune checkpoint inhibitors, better known as immunotherapies, have revolutionized oncological treatment, allowing long-lasting and even curative tumor responses in various neoplasms. Their use, however, is associated with immunological adverse effects, among which neurological adverse effects represent a rare but clinically relevant entity.</div><div>This article addresses the epidemiology, classification, diagnostic keys and management of the most frequent neurological complications of immunotherapies, providing health professionals, and especially neurologists, with key tools for their recognition and timely treatment.</div></div>\",\"PeriodicalId\":31544,\"journal\":{\"name\":\"Revista Medica Clinica Las Condes\",\"volume\":\"36 3\",\"pages\":\"Pages 146-155\"},\"PeriodicalIF\":0.4000,\"publicationDate\":\"2025-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revista Medica Clinica Las Condes\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0716864025000434\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista Medica Clinica Las Condes","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0716864025000434","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Complicaciones neurológicas relacionadas con la inmunoterapia en pacientes oncológicos
Immune checkpoint inhibitors, better known as immunotherapies, have revolutionized oncological treatment, allowing long-lasting and even curative tumor responses in various neoplasms. Their use, however, is associated with immunological adverse effects, among which neurological adverse effects represent a rare but clinically relevant entity.
This article addresses the epidemiology, classification, diagnostic keys and management of the most frequent neurological complications of immunotherapies, providing health professionals, and especially neurologists, with key tools for their recognition and timely treatment.